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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UNC5A
Full Name:
Netrin receptor UNC5A
Alias:
Protein unc-5 homolog 1;Protein unc-5 homolog A
Type:
Mass (Da):
92932
Number AA:
842
UniProt ID:
Q6ZN44
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
L
A
A
W
L
R
G
S
G
A
Q
Q
S
A
T
Site 2
S232
N
I
V
A
R
R
R
S
A
S
A
A
V
I
V
Site 3
S336
R
K
K
E
G
L
D
S
D
V
A
D
S
S
I
Site 4
S342
D
S
D
V
A
D
S
S
I
L
T
S
G
F
Q
Site 5
S352
T
S
G
F
Q
P
V
S
I
K
P
S
K
A
D
Site 6
S356
Q
P
V
S
I
K
P
S
K
A
D
N
P
H
L
Site 7
T365
A
D
N
P
H
L
L
T
I
Q
P
D
L
S
T
Site 8
S371
L
T
I
Q
P
D
L
S
T
T
T
T
T
Y
Q
Site 9
T375
P
D
L
S
T
T
T
T
T
Y
Q
G
S
L
C
Site 10
T376
D
L
S
T
T
T
T
T
Y
Q
G
S
L
C
P
Site 11
S380
T
T
T
T
Y
Q
G
S
L
C
P
R
Q
D
G
Site 12
S389
C
P
R
Q
D
G
P
S
P
K
F
Q
L
T
N
Site 13
T395
P
S
P
K
F
Q
L
T
N
G
H
L
L
S
P
Site 14
S401
L
T
N
G
H
L
L
S
P
L
G
G
G
R
H
Site 15
T409
P
L
G
G
G
R
H
T
L
H
H
S
S
P
T
Site 16
S413
G
R
H
T
L
H
H
S
S
P
T
S
E
A
E
Site 17
S414
R
H
T
L
H
H
S
S
P
T
S
E
A
E
E
Site 18
S417
L
H
H
S
S
P
T
S
E
A
E
E
F
V
S
Site 19
S424
S
E
A
E
E
F
V
S
R
L
S
T
Q
N
Y
Site 20
S427
E
E
F
V
S
R
L
S
T
Q
N
Y
F
R
S
Site 21
T428
E
F
V
S
R
L
S
T
Q
N
Y
F
R
S
L
Site 22
Y431
S
R
L
S
T
Q
N
Y
F
R
S
L
P
R
G
Site 23
S434
S
T
Q
N
Y
F
R
S
L
P
R
G
T
S
N
Site 24
T439
F
R
S
L
P
R
G
T
S
N
M
T
Y
G
T
Site 25
S440
R
S
L
P
R
G
T
S
N
M
T
Y
G
T
F
Site 26
Y444
R
G
T
S
N
M
T
Y
G
T
F
N
F
L
G
Site 27
T446
T
S
N
M
T
Y
G
T
F
N
F
L
G
G
R
Site 28
Y479
R
G
K
I
Y
E
I
Y
L
T
L
H
K
P
E
Site 29
T481
K
I
Y
E
I
Y
L
T
L
H
K
P
E
D
V
Site 30
S527
M
D
H
C
G
E
P
S
P
D
S
W
S
L
R
Site 31
S530
C
G
E
P
S
P
D
S
W
S
L
R
L
K
K
Site 32
S532
E
P
S
P
D
S
W
S
L
R
L
K
K
Q
S
Site 33
S539
S
L
R
L
K
K
Q
S
C
E
G
S
W
E
D
Site 34
S543
K
K
Q
S
C
E
G
S
W
E
D
V
L
H
L
Site 35
Y559
E
E
A
P
S
H
L
Y
Y
C
Q
L
E
A
S
Site 36
Y560
E
A
P
S
H
L
Y
Y
C
Q
L
E
A
S
A
Site 37
S586
A
L
V
G
E
A
L
S
V
A
A
A
K
R
L
Site 38
Y613
L
E
Y
N
I
R
V
Y
C
L
H
D
T
H
D
Site 39
T618
R
V
Y
C
L
H
D
T
H
D
A
L
K
E
V
Site 40
S648
R
V
L
H
F
K
D
S
Y
H
N
L
R
L
S
Site 41
Y649
V
L
H
F
K
D
S
Y
H
N
L
R
L
S
I
Site 42
S655
S
Y
H
N
L
R
L
S
I
H
D
V
P
S
S
Site 43
S661
L
S
I
H
D
V
P
S
S
L
W
K
S
K
L
Site 44
S662
S
I
H
D
V
P
S
S
L
W
K
S
K
L
L
Site 45
S666
V
P
S
S
L
W
K
S
K
L
L
V
S
Y
Q
Site 46
S671
W
K
S
K
L
L
V
S
Y
Q
E
I
P
F
Y
Site 47
Y672
K
S
K
L
L
V
S
Y
Q
E
I
P
F
Y
H
Site 48
T691
T
Q
R
Y
L
H
C
T
F
T
L
E
R
V
S
Site 49
T693
R
Y
L
H
C
T
F
T
L
E
R
V
S
P
S
Site 50
S698
T
F
T
L
E
R
V
S
P
S
T
S
D
L
A
Site 51
S700
T
L
E
R
V
S
P
S
T
S
D
L
A
C
K
Site 52
S702
E
R
V
S
P
S
T
S
D
L
A
C
K
L
W
Site 53
S719
Q
V
E
G
D
G
Q
S
F
S
I
N
F
N
I
Site 54
S721
E
G
D
G
Q
S
F
S
I
N
F
N
I
T
K
Site 55
S765
L
I
R
Q
K
I
I
S
S
L
D
P
P
C
R
Site 56
S766
I
R
Q
K
I
I
S
S
L
D
P
P
C
R
R
Site 57
T779
R
R
G
A
D
W
R
T
L
A
Q
K
L
H
L
Site 58
S788
A
Q
K
L
H
L
D
S
H
L
S
F
F
A
S
Site 59
S791
L
H
L
D
S
H
L
S
F
F
A
S
K
P
S
Site 60
S795
S
H
L
S
F
F
A
S
K
P
S
P
T
A
M
Site 61
T836
Q
P
D
A
G
L
F
T
V
S
E
A
E
C
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation