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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LEKR1
Full Name:
Leucine-, glutamate- and lysine-rich protein 1
Alias:
Type:
Mass (Da):
45158
Number AA:
388
UniProt ID:
Q6ZMV7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
L
L
K
E
K
E
D
S
L
M
T
C
Q
Q
I
Site 2
T25
K
A
L
Q
E
E
L
T
V
K
E
K
Q
E
E
Site 3
T48
A
E
N
E
L
E
I
T
K
T
L
L
N
Q
T
Site 4
T50
N
E
L
E
I
T
K
T
L
L
N
Q
T
R
E
Site 5
T61
Q
T
R
E
E
V
L
T
L
K
N
E
R
E
L
Site 6
S72
E
R
E
L
M
L
I
S
H
Q
K
S
I
E
Q
Site 7
S76
M
L
I
S
H
Q
K
S
I
E
Q
L
Q
E
T
Site 8
T83
S
I
E
Q
L
Q
E
T
L
R
Q
K
L
L
S
Site 9
S90
T
L
R
Q
K
L
L
S
D
D
N
W
K
E
K
Site 10
S154
E
E
L
Q
M
K
I
S
D
L
I
T
G
A
T
Site 11
T158
M
K
I
S
D
L
I
T
G
A
T
R
D
L
R
Site 12
T170
D
L
R
Q
E
V
T
T
L
K
E
K
L
H
K
Site 13
S178
L
K
E
K
L
H
K
S
H
T
R
Y
T
E
E
Site 14
Y182
L
H
K
S
H
T
R
Y
T
E
E
S
N
S
K
Site 15
T183
H
K
S
H
T
R
Y
T
E
E
S
N
S
K
E
Site 16
S186
H
T
R
Y
T
E
E
S
N
S
K
E
K
E
I
Site 17
S188
R
Y
T
E
E
S
N
S
K
E
K
E
I
E
N
Site 18
S213
R
L
K
K
E
I
D
S
N
D
S
V
S
E
N
Site 19
S216
K
E
I
D
S
N
D
S
V
S
E
N
L
R
K
Site 20
S218
I
D
S
N
D
S
V
S
E
N
L
R
K
E
M
Site 21
S229
R
K
E
M
E
Q
K
S
D
E
L
K
R
V
M
Site 22
S249
L
I
E
Q
F
N
Q
S
Q
E
E
N
T
F
L
Site 23
T254
N
Q
S
Q
E
E
N
T
F
L
Q
E
T
V
R
Site 24
T259
E
N
T
F
L
Q
E
T
V
R
R
E
C
E
E
Site 25
T271
C
E
E
R
F
E
L
T
E
A
L
S
Q
A
R
Site 26
S275
F
E
L
T
E
A
L
S
Q
A
R
E
Q
L
L
Site 27
S285
R
E
Q
L
L
E
L
S
K
L
R
G
S
L
P
Site 28
S290
E
L
S
K
L
R
G
S
L
P
F
S
P
C
S
Site 29
S294
L
R
G
S
L
P
F
S
P
C
S
L
S
K
G
Site 30
S297
S
L
P
F
S
P
C
S
L
S
K
G
S
L
T
Site 31
S299
P
F
S
P
C
S
L
S
K
G
S
L
T
S
P
Site 32
S311
T
S
P
A
A
A
V
S
N
H
G
E
R
S
L
Site 33
S317
V
S
N
H
G
E
R
S
L
A
R
L
N
S
E
Site 34
S323
R
S
L
A
R
L
N
S
E
K
G
I
Q
I
P
Site 35
S336
I
P
N
L
R
G
V
S
K
P
T
T
F
P
T
Site 36
T340
R
G
V
S
K
P
T
T
F
P
T
S
D
K
P
Site 37
S344
K
P
T
T
F
P
T
S
D
K
P
K
R
V
R
Site 38
S352
D
K
P
K
R
V
R
S
G
V
P
I
L
P
Q
Site 39
S369
P
P
R
G
G
A
S
S
A
N
E
T
R
Q
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation