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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SMEK3P
Full Name:
Putative SMEK homolog 3
Alias:
Type:
Uncharacterized protein
Mass (Da):
95776
Number AA:
832
UniProt ID:
Q6ZMV5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
L
R
Y
S
V
K
V
Y
V
L
N
E
D
E
E
Site 2
T24
E
E
W
N
N
L
G
T
G
Q
V
S
S
T
Y
Site 3
S29
L
G
T
G
Q
V
S
S
T
Y
D
E
Q
F
Q
Site 4
Y31
T
G
Q
V
S
S
T
Y
D
E
Q
F
Q
G
M
Site 5
S46
S
L
L
V
R
S
D
S
D
G
S
V
I
L
R
Site 6
S49
V
R
S
D
S
D
G
S
V
I
L
R
S
Q
I
Site 7
S54
D
G
S
V
I
L
R
S
Q
I
P
P
D
R
P
Site 8
Y62
Q
I
P
P
D
R
P
Y
G
K
Y
Q
E
T
L
Site 9
Y65
P
D
R
P
Y
G
K
Y
Q
E
T
L
I
V
W
Site 10
S106
Q
A
Q
G
K
D
P
S
I
Q
T
T
V
N
I
Site 11
T110
K
D
P
S
I
Q
T
T
V
N
I
S
D
E
P
Site 12
S114
I
Q
T
T
V
N
I
S
D
E
P
E
E
D
F
Site 13
S128
F
N
E
M
S
V
I
S
N
M
V
V
L
P
D
Site 14
S154
I
V
T
S
V
F
S
S
P
V
T
D
R
E
R
Site 15
T157
S
V
F
S
S
P
V
T
D
R
E
R
L
A
E
Site 16
Y171
E
I
L
K
N
E
A
Y
I
P
K
L
L
Q
L
Site 17
T243
K
R
H
R
D
F
L
T
N
D
A
K
F
K
E
Site 18
T266
L
R
Q
K
I
H
Q
T
Y
R
L
Q
Y
I
Y
Site 19
Y271
H
Q
T
Y
R
L
Q
Y
I
Y
D
I
L
L
P
Site 20
Y314
Q
K
D
H
K
F
L
Y
E
V
F
A
Q
L
K
Site 21
T325
A
Q
L
K
D
E
T
T
H
D
D
R
R
C
E
Site 22
S344
F
K
E
L
C
S
F
S
Q
A
L
Q
P
Q
S
Site 23
S351
S
Q
A
L
Q
P
Q
S
K
D
A
L
F
E
T
Site 24
T358
S
K
D
A
L
F
E
T
L
I
Q
L
G
V
L
Site 25
S394
C
A
Y
L
V
E
Y
S
P
S
R
I
R
E
F
Site 26
S404
R
I
R
E
F
I
I
S
E
A
H
V
C
K
D
Site 27
T427
I
K
Q
M
I
C
D
T
D
P
E
L
G
G
A
Site 28
T452
L
D
P
R
N
M
L
T
T
P
E
K
S
E
R
Site 29
T453
D
P
R
N
M
L
T
T
P
E
K
S
E
R
S
Site 30
S457
M
L
T
T
P
E
K
S
E
R
S
E
F
L
H
Site 31
S483
A
P
L
L
A
A
T
S
E
H
N
C
E
E
D
Site 32
Y495
E
E
D
D
I
A
G
Y
D
K
S
K
N
C
P
Site 33
Y532
H
T
F
Y
I
R
S
Y
I
L
N
K
D
L
L
Site 34
Y572
I
C
L
N
D
E
A
Y
N
N
Y
I
I
K
G
Site 35
Y575
N
D
E
A
Y
N
N
Y
I
I
K
G
N
L
F
Site 36
T594
N
A
L
L
D
N
G
T
R
Y
N
M
L
N
S
Site 37
Y596
L
L
D
N
G
T
R
Y
N
M
L
N
S
A
I
Site 38
Y627
S
H
I
V
E
K
F
Y
N
T
L
E
S
I
E
Site 39
Y635
N
T
L
E
S
I
E
Y
V
Q
T
F
K
G
L
Site 40
T638
E
S
I
E
Y
V
Q
T
F
K
G
L
K
I
K
Site 41
Y646
F
K
G
L
K
I
K
Y
E
K
E
R
D
R
Q
Site 42
S654
E
K
E
R
D
R
Q
S
Q
I
Q
K
N
L
H
Site 43
T706
D
D
D
E
F
M
E
T
K
R
T
Q
E
G
E
Site 44
T709
E
F
M
E
T
K
R
T
Q
E
G
E
A
V
M
Site 45
T726
L
E
D
D
D
K
F
T
E
T
K
R
T
H
Q
Site 46
T731
K
F
T
E
T
K
R
T
H
Q
E
G
E
A
V
Site 47
T751
D
D
D
E
F
M
E
T
K
R
N
Q
E
H
E
Site 48
S763
E
H
E
G
K
V
D
S
P
K
R
T
S
S
G
Site 49
T767
K
V
D
S
P
K
R
T
S
S
G
D
F
K
F
Site 50
S768
V
D
S
P
K
R
T
S
S
G
D
F
K
F
S
Site 51
S769
D
S
P
K
R
T
S
S
G
D
F
K
F
S
S
Site 52
S775
S
S
G
D
F
K
F
S
S
S
Y
S
A
C
A
Site 53
S776
S
G
D
F
K
F
S
S
S
Y
S
A
C
A
A
Site 54
Y778
D
F
K
F
S
S
S
Y
S
A
C
A
A
I
G
Site 55
S792
G
T
G
S
P
S
G
S
S
V
V
R
L
V
D
Site 56
S793
T
G
S
P
S
G
S
S
V
V
R
L
V
D
H
Site 57
T822
E
E
D
K
E
D
E
T
S
P
K
K
K
P
H
Site 58
S823
E
D
K
E
D
E
T
S
P
K
K
K
P
H
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation