PhosphoNET

           
Protein Info 
   
Short Name:  NAPRT1
Full Name:  Nicotinate phosphoribosyltransferase
Alias:  EC 2.4.2.11; Nicotinate phosphoribosyltransferase domain containing 1; PNCB; PP3856
Type:  Enzyme - Phosphoribosyltransferase
Mass (Da):  57578
Number AA:  538
UniProt ID:  Q6XQN6
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829     Uniprot OncoNet
Molecular Function:  GO:0004516     PhosphoSite+ KinaseNET
Biological Process:  GO:0019674  GO:0019363  GO:0006979 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T18AAARPLLTDLYQATM
Site 2Y21RPLLTDLYQATMALG
Site 3T24LTDLYQATMALGYWR
Site 4Y29QATMALGYWRAGRAR
Site 5T88ASVLPPDTDPAFFEH
Site 6T181QGPDGGLTASTYSYL
Site 7S183PDGGLTASTYSYLGG
Site 8T184DGGLTASTYSYLGGF
Site 9Y185GGLTASTYSYLGGFD
Site 10S186GLTASTYSYLGGFDS
Site 11Y187LTASTYSYLGGFDSS
Site 12S193SYLGGFDSSSNVLAG
Site 13S194YLGGFDSSSNVLAGQ
Site 14S220HSFVTSFSGSEVPPD
Site 15S222FVTSFSGSEVPPDPM
Site 16T289AFQGLLDTYSVWRSG
Site 17Y290FQGLLDTYSVWRSGL
Site 18S291QGLLDTYSVWRSGLP
Site 19S295DTYSVWRSGLPNFLA
Site 20T409GQPRMKLTEDPEKQT
Site 21T416TEDPEKQTLPGSKAA
Site 22S420EKQTLPGSKAAFRLL
Site 23S432RLLGSDGSPLMDMLQ
Site 24T464PGAQEPCTVRPAQVE
Site 25S489QLCEPLPSLAESRAL
Site 26S500SRALAQLSLSRLSPE
Site 27S502ALAQLSLSRLSPEHR
Site 28S505QLSLSRLSPEHRRLR
Site 29S513PEHRRLRSPAQYQVV
Site 30Y517RLRSPAQYQVVLSER
Site 31S537NSLCAGQSP______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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