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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAT4
Full Name:
Protocadherin Fat 4
Alias:
Cadherin family member 14;FAT tumor suppressor homolog 4;Fat-like cadherin protein FAT-J
Type:
Mass (Da):
351191
Number AA:
3222
UniProt ID:
Q6V0I7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007156
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
D
L
A
P
D
R
A
T
G
R
P
W
L
P
L
Site 2
T643
P
V
S
G
R
L
S
T
I
S
S
L
D
R
E
Site 3
S645
S
G
R
L
S
T
I
S
S
L
D
R
E
E
Q
Site 4
S646
G
R
L
S
T
I
S
S
L
D
R
E
E
Q
A
Site 5
S869
Y
Q
L
K
V
V
A
S
G
G
T
V
T
G
D
Site 6
T872
K
V
V
A
S
G
G
T
V
T
G
D
T
M
V
Site 7
S1781
L
V
T
Y
T
I
I
S
G
A
D
D
S
F
R
Site 8
Y2120
D
R
E
E
V
S
N
Y
T
L
T
V
V
A
T
Site 9
S2206
N
Q
E
F
R
I
D
S
V
T
G
A
I
T
V
Site 10
S2389
D
V
L
L
V
N
A
S
D
A
D
A
S
K
N
Site 11
S2394
N
A
S
D
A
D
A
S
K
N
A
V
I
R
I
Site 12
T2549
D
G
G
S
F
P
K
T
D
S
T
T
V
T
V
Site 13
S2846
D
R
Y
R
I
R
V
S
A
H
D
S
G
W
T
Site 14
Y3978
K
H
C
E
L
N
S
Y
G
F
E
E
L
S
Y
Site 15
Y3985
Y
G
F
E
E
L
S
Y
M
E
F
P
S
L
D
Site 16
Y3997
S
L
D
P
N
N
N
Y
I
Y
V
K
F
A
T
Site 17
T4099
V
A
V
S
D
D
W
T
L
D
V
Q
P
N
R
Site 18
Y4565
D
P
D
N
I
P
P
Y
G
D
D
M
T
V
R
Site 19
T4570
P
P
Y
G
D
D
M
T
V
R
K
Q
P
E
G
Site 20
Y4593
R
E
N
P
Y
L
I
Y
D
E
T
D
I
P
H
Site 21
T4596
P
Y
L
I
Y
D
E
T
D
I
P
H
N
S
E
Site 22
S4602
E
T
D
I
P
H
N
S
E
T
I
P
S
A
P
Site 23
T4604
D
I
P
H
N
S
E
T
I
P
S
A
P
L
A
Site 24
S4607
H
N
S
E
T
I
P
S
A
P
L
A
S
P
E
Site 25
S4612
I
P
S
A
P
L
A
S
P
E
Q
E
I
E
H
Site 26
Y4620
P
E
Q
E
I
E
H
Y
D
I
D
N
A
S
S
Site 27
S4626
H
Y
D
I
D
N
A
S
S
I
A
P
S
D
A
Site 28
S4627
Y
D
I
D
N
A
S
S
I
A
P
S
D
A
D
Site 29
S4631
N
A
S
S
I
A
P
S
D
A
D
I
I
Q
H
Site 30
Y4639
D
A
D
I
I
Q
H
Y
K
Q
F
R
S
H
T
Site 31
T4646
Y
K
Q
F
R
S
H
T
P
K
F
S
I
Q
R
Site 32
S4650
R
S
H
T
P
K
F
S
I
Q
R
H
S
P
L
Site 33
S4655
K
F
S
I
Q
R
H
S
P
L
G
F
A
R
Q
Site 34
S4663
P
L
G
F
A
R
Q
S
P
M
P
L
G
A
S
Site 35
S4671
P
M
P
L
G
A
S
S
L
T
Y
Q
P
S
Y
Site 36
T4673
P
L
G
A
S
S
L
T
Y
Q
P
S
Y
G
Q
Site 37
Y4674
L
G
A
S
S
L
T
Y
Q
P
S
Y
G
Q
G
Site 38
S4677
S
S
L
T
Y
Q
P
S
Y
G
Q
G
L
R
T
Site 39
Y4678
S
L
T
Y
Q
P
S
Y
G
Q
G
L
R
T
S
Site 40
T4684
S
Y
G
Q
G
L
R
T
S
S
L
S
H
S
A
Site 41
S4685
Y
G
Q
G
L
R
T
S
S
L
S
H
S
A
C
Site 42
S4686
G
Q
G
L
R
T
S
S
L
S
H
S
A
C
P
Site 43
S4688
G
L
R
T
S
S
L
S
H
S
A
C
P
T
P
Site 44
S4690
R
T
S
S
L
S
H
S
A
C
P
T
P
N
P
Site 45
T4694
L
S
H
S
A
C
P
T
P
N
P
L
S
R
H
Site 46
S4699
C
P
T
P
N
P
L
S
R
H
S
P
A
P
F
Site 47
S4702
P
N
P
L
S
R
H
S
P
A
P
F
S
K
S
Site 48
S4707
R
H
S
P
A
P
F
S
K
S
S
T
F
Y
R
Site 49
S4709
S
P
A
P
F
S
K
S
S
T
F
Y
R
N
S
Site 50
S4710
P
A
P
F
S
K
S
S
T
F
Y
R
N
S
P
Site 51
T4711
A
P
F
S
K
S
S
T
F
Y
R
N
S
P
A
Site 52
Y4713
F
S
K
S
S
T
F
Y
R
N
S
P
A
R
E
Site 53
S4716
S
S
T
F
Y
R
N
S
P
A
R
E
L
H
L
Site 54
T4730
L
P
I
R
D
G
N
T
L
E
M
H
G
D
T
Site 55
Y4745
C
Q
P
G
I
F
N
Y
A
T
R
L
G
R
R
Site 56
T4747
P
G
I
F
N
Y
A
T
R
L
G
R
R
S
K
Site 57
S4753
A
T
R
L
G
R
R
S
K
S
P
Q
A
M
A
Site 58
S4755
R
L
G
R
R
S
K
S
P
Q
A
M
A
S
H
Site 59
S4761
K
S
P
Q
A
M
A
S
H
G
S
R
P
G
S
Site 60
S4764
Q
A
M
A
S
H
G
S
R
P
G
S
R
L
K
Site 61
S4768
S
H
G
S
R
P
G
S
R
L
K
Q
P
I
G
Site 62
S4788
S
S
P
P
V
G
L
S
I
E
E
V
E
R
L
Site 63
T4797
E
E
V
E
R
L
N
T
P
R
P
R
N
P
S
Site 64
S4804
T
P
R
P
R
N
P
S
I
C
S
A
D
H
G
Site 65
S4807
P
R
N
P
S
I
C
S
A
D
H
G
R
S
S
Site 66
S4814
S
A
D
H
G
R
S
S
S
E
E
D
C
R
R
Site 67
S4815
A
D
H
G
R
S
S
S
E
E
D
C
R
R
P
Site 68
S4824
E
D
C
R
R
P
L
S
R
T
R
N
P
A
D
Site 69
T4826
C
R
R
P
L
S
R
T
R
N
P
A
D
G
I
Site 70
S4838
D
G
I
P
A
P
E
S
S
S
D
S
D
S
H
Site 71
S4839
G
I
P
A
P
E
S
S
S
D
S
D
S
H
E
Site 72
S4840
I
P
A
P
E
S
S
S
D
S
D
S
H
E
S
Site 73
S4842
A
P
E
S
S
S
D
S
D
S
H
E
S
F
T
Site 74
S4844
E
S
S
S
D
S
D
S
H
E
S
F
T
C
S
Site 75
S4847
S
D
S
D
S
H
E
S
F
T
C
S
E
M
E
Site 76
T4849
S
D
S
H
E
S
F
T
C
S
E
M
E
Y
D
Site 77
S4851
S
H
E
S
F
T
C
S
E
M
E
Y
D
R
E
Site 78
Y4855
F
T
C
S
E
M
E
Y
D
R
E
K
P
M
V
Site 79
Y4863
D
R
E
K
P
M
V
Y
T
S
R
M
P
K
L
Site 80
S4865
E
K
P
M
V
Y
T
S
R
M
P
K
L
S
Q
Site 81
S4871
T
S
R
M
P
K
L
S
Q
V
N
E
S
D
A
Site 82
S4876
K
L
S
Q
V
N
E
S
D
A
D
D
E
D
N
Site 83
Y4884
D
A
D
D
E
D
N
Y
G
A
R
L
K
P
R
Site 84
Y4893
A
R
L
K
P
R
R
Y
H
G
R
R
A
E
G
Site 85
T4916
A
P
G
T
A
D
N
T
L
P
M
K
L
G
Q
Site 86
T4927
K
L
G
Q
Q
A
G
T
F
N
W
D
N
L
L
Site 87
Y4943
W
G
P
G
F
G
H
Y
V
D
V
F
K
D
L
Site 88
S4952
D
V
F
K
D
L
A
S
L
P
E
K
A
A
A
Site 89
Y4980
K
D
G
E
A
E
Q
Y
V
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation