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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
VIT
Full Name:
Vitrin
Alias:
Type:
Mass (Da):
73930
Number AA:
678
UniProt ID:
Q6UXI7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y71
A
G
C
Q
D
P
K
Y
H
V
Y
G
T
D
V
Site 2
T76
P
K
Y
H
V
Y
G
T
D
V
Y
A
S
Y
S
Site 3
Y79
H
V
Y
G
T
D
V
Y
A
S
Y
S
S
V
C
Site 4
S98
H
S
G
V
L
D
N
S
G
G
K
I
L
V
R
Site 5
S111
V
R
K
V
A
G
Q
S
G
Y
K
G
S
Y
S
Site 6
S116
G
Q
S
G
Y
K
G
S
Y
S
N
G
V
Q
S
Site 7
S118
S
G
Y
K
G
S
Y
S
N
G
V
Q
S
L
S
Site 8
S123
S
Y
S
N
G
V
Q
S
L
S
L
P
R
W
R
Site 9
S125
S
N
G
V
Q
S
L
S
L
P
R
W
R
E
S
Site 10
S132
S
L
P
R
W
R
E
S
F
I
V
L
E
S
K
Site 11
S138
E
S
F
I
V
L
E
S
K
P
K
K
G
V
T
Site 12
T145
S
K
P
K
K
G
V
T
Y
P
S
A
L
T
Y
Site 13
Y146
K
P
K
K
G
V
T
Y
P
S
A
L
T
Y
S
Site 14
S148
K
K
G
V
T
Y
P
S
A
L
T
Y
S
S
S
Site 15
T151
V
T
Y
P
S
A
L
T
Y
S
S
S
K
S
P
Site 16
Y152
T
Y
P
S
A
L
T
Y
S
S
S
K
S
P
A
Site 17
S153
Y
P
S
A
L
T
Y
S
S
S
K
S
P
A
A
Site 18
S154
P
S
A
L
T
Y
S
S
S
K
S
P
A
A
Q
Site 19
S155
S
A
L
T
Y
S
S
S
K
S
P
A
A
Q
A
Site 20
S157
L
T
Y
S
S
S
K
S
P
A
A
Q
A
G
E
Site 21
Y169
A
G
E
T
T
K
A
Y
Q
R
P
P
I
P
G
Site 22
T178
R
P
P
I
P
G
T
T
A
Q
P
V
T
L
M
Site 23
T198
T
V
A
V
A
T
P
T
T
L
P
R
P
S
P
Site 24
T199
V
A
V
A
T
P
T
T
L
P
R
P
S
P
S
Site 25
S204
P
T
T
L
P
R
P
S
P
S
A
A
S
T
T
Site 26
S206
T
L
P
R
P
S
P
S
A
A
S
T
T
S
I
Site 27
S209
R
P
S
P
S
A
A
S
T
T
S
I
P
R
P
Site 28
T210
P
S
P
S
A
A
S
T
T
S
I
P
R
P
Q
Site 29
T211
S
P
S
A
A
S
T
T
S
I
P
R
P
Q
S
Site 30
S212
P
S
A
A
S
T
T
S
I
P
R
P
Q
S
V
Site 31
S218
T
S
I
P
R
P
Q
S
V
G
H
R
S
Q
E
Site 32
S223
P
Q
S
V
G
H
R
S
Q
E
M
D
L
W
S
Site 33
S230
S
Q
E
M
D
L
W
S
T
A
T
Y
T
S
S
Site 34
T233
M
D
L
W
S
T
A
T
Y
T
S
S
Q
N
R
Site 35
Y234
D
L
W
S
T
A
T
Y
T
S
S
Q
N
R
P
Site 36
S237
S
T
A
T
Y
T
S
S
Q
N
R
P
R
A
D
Site 37
S253
G
I
Q
R
Q
D
P
S
G
A
A
F
Q
K
P
Site 38
S276
L
V
P
K
E
E
L
S
T
Q
S
L
E
P
V
Site 39
T277
V
P
K
E
E
L
S
T
Q
S
L
E
P
V
S
Site 40
S279
K
E
E
L
S
T
Q
S
L
E
P
V
S
L
G
Site 41
S284
T
Q
S
L
E
P
V
S
L
G
D
P
N
C
K
Site 42
S301
L
S
F
L
I
D
G
S
T
S
I
G
K
R
R
Site 43
T302
S
F
L
I
D
G
S
T
S
I
G
K
R
R
F
Site 44
T349
A
T
H
F
N
L
K
T
H
T
N
S
R
D
L
Site 45
T358
T
N
S
R
D
L
K
T
A
I
E
K
I
T
Q
Site 46
T364
K
T
A
I
E
K
I
T
Q
R
G
G
L
S
N
Site 47
S370
I
T
Q
R
G
G
L
S
N
V
G
R
A
I
S
Site 48
Y439
A
A
E
N
E
K
Q
Y
V
V
E
P
N
F
A
Site 49
Y457
V
C
R
T
N
G
F
Y
S
L
H
V
Q
S
W
Site 50
T470
S
W
F
G
L
H
K
T
L
Q
P
L
V
K
R
Site 51
T481
L
V
K
R
V
C
D
T
D
R
L
A
C
S
K
Site 52
S487
D
T
D
R
L
A
C
S
K
T
C
L
N
S
A
Site 53
T489
D
R
L
A
C
S
K
T
C
L
N
S
A
D
I
Site 54
S505
F
V
I
D
G
S
S
S
V
G
T
G
N
F
R
Site 55
T508
D
G
S
S
S
V
G
T
G
N
F
R
T
V
L
Site 56
S528
L
T
K
E
F
E
I
S
D
T
D
T
R
I
G
Site 57
T530
K
E
F
E
I
S
D
T
D
T
R
I
G
A
V
Site 58
T532
F
E
I
S
D
T
D
T
R
I
G
A
V
Q
Y
Site 59
T540
R
I
G
A
V
Q
Y
T
Y
E
Q
R
L
E
F
Site 60
Y541
I
G
A
V
Q
Y
T
Y
E
Q
R
L
E
F
G
Site 61
Y552
L
E
F
G
F
D
K
Y
S
S
K
P
D
I
L
Site 62
S553
E
F
G
F
D
K
Y
S
S
K
P
D
I
L
N
Site 63
S554
F
G
F
D
K
Y
S
S
K
P
D
I
L
N
A
Site 64
Y567
N
A
I
K
R
V
G
Y
W
S
G
G
T
S
T
Site 65
S569
I
K
R
V
G
Y
W
S
G
G
T
S
T
G
A
Site 66
S573
G
Y
W
S
G
G
T
S
T
G
A
A
I
N
F
Site 67
T601
R
K
L
M
I
L
I
T
D
G
R
S
Y
D
D
Site 68
S605
I
L
I
T
D
G
R
S
Y
D
D
V
R
I
P
Site 69
Y606
L
I
T
D
G
R
S
Y
D
D
V
R
I
P
A
Site 70
T641
E
E
L
E
V
I
A
T
H
P
A
R
D
H
S
Site 71
S648
T
H
P
A
R
D
H
S
F
F
V
D
E
F
D
Site 72
Y660
E
F
D
N
L
H
Q
Y
V
P
R
I
I
Q
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation