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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SASS6
Full Name:
Spindle assembly abnormal protein 6 homolog
Alias:
CEP170; DKFZp761A078; FLJ22097; HsSAS-6; SAS6; SAS-6; Spindle assembly 6; Spindle assembly abnormal protein 6
Type:
Cell cycle regulation
Mass (Da):
74397
Number AA:
657
UniProt ID:
Q6UVJ0
International Prot ID:
IPI00375578
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005814
GO:0005815
GO:0043226
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007099
GO:0007049
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
D
C
E
E
R
R
V
S
I
R
M
S
I
E
L
Site 2
S29
R
R
V
S
I
R
M
S
I
E
L
Q
S
V
S
Site 3
S34
R
M
S
I
E
L
Q
S
V
S
N
P
V
H
R
Site 4
S36
S
I
E
L
Q
S
V
S
N
P
V
H
R
K
D
Site 5
T49
K
D
L
V
I
R
L
T
D
D
T
D
P
F
F
Site 6
T52
V
I
R
L
T
D
D
T
D
P
F
F
L
Y
N
Site 7
Y58
D
T
D
P
F
F
L
Y
N
L
V
I
S
E
E
Site 8
S63
F
L
Y
N
L
V
I
S
E
E
D
F
Q
S
L
Site 9
S69
I
S
E
E
D
F
Q
S
L
K
F
Q
Q
G
L
Site 10
T135
T
N
P
F
K
H
L
T
H
L
S
L
K
L
L
Site 11
S138
F
K
H
L
T
H
L
S
L
K
L
L
P
G
N
Site 12
S160
L
A
G
C
L
K
C
S
K
E
E
K
L
S
L
Site 13
S166
C
S
K
E
E
K
L
S
L
M
Q
S
L
D
D
Site 14
S170
E
K
L
S
L
M
Q
S
L
D
D
A
T
K
Q
Site 15
T175
M
Q
S
L
D
D
A
T
K
Q
L
D
F
T
R
Site 16
T184
Q
L
D
F
T
R
K
T
L
A
E
K
K
Q
E
Site 17
S201
K
L
R
N
E
W
A
S
H
T
A
A
L
T
N
Site 18
T207
A
S
H
T
A
A
L
T
N
K
H
S
Q
E
L
Site 19
S211
A
A
L
T
N
K
H
S
Q
E
L
T
N
E
K
Site 20
T215
N
K
H
S
Q
E
L
T
N
E
K
E
K
A
L
Site 21
S255
H
Q
L
Q
N
R
L
S
E
L
E
A
A
N
K
Site 22
T265
E
A
A
N
K
D
L
T
E
R
K
Y
K
G
D
Site 23
Y269
K
D
L
T
E
R
K
Y
K
G
D
S
T
I
R
Site 24
S273
E
R
K
Y
K
G
D
S
T
I
R
E
L
K
A
Site 25
T274
R
K
Y
K
G
D
S
T
I
R
E
L
K
A
K
Site 26
S283
R
E
L
K
A
K
L
S
G
V
E
E
E
L
Q
Site 27
T292
V
E
E
E
L
Q
R
T
K
Q
E
V
L
S
L
Site 28
S298
R
T
K
Q
E
V
L
S
L
R
R
E
N
S
T
Site 29
S304
L
S
L
R
R
E
N
S
T
L
D
V
E
C
H
Site 30
T305
S
L
R
R
E
N
S
T
L
D
V
E
C
H
E
Site 31
T347
R
T
K
E
A
F
D
T
I
Q
E
Q
K
V
V
Site 32
T396
K
L
Q
G
D
L
K
T
L
M
G
K
L
K
L
Site 33
T406
G
K
L
K
L
K
N
T
V
T
I
Q
Q
E
K
Site 34
S435
E
L
Q
D
V
G
Q
S
L
R
I
K
E
Q
E
Site 35
T472
K
N
N
E
K
L
I
T
W
L
N
K
E
L
N
Site 36
S493
K
Q
D
V
L
G
P
S
T
T
P
P
A
H
S
Site 37
T494
Q
D
V
L
G
P
S
T
T
P
P
A
H
S
S
Site 38
T495
D
V
L
G
P
S
T
T
P
P
A
H
S
S
S
Site 39
S500
S
T
T
P
P
A
H
S
S
S
N
T
I
R
S
Site 40
S501
T
T
P
P
A
H
S
S
S
N
T
I
R
S
G
Site 41
S502
T
P
P
A
H
S
S
S
N
T
I
R
S
G
I
Site 42
T504
P
A
H
S
S
S
N
T
I
R
S
G
I
S
P
Site 43
S507
S
S
S
N
T
I
R
S
G
I
S
P
N
L
N
Site 44
S510
N
T
I
R
S
G
I
S
P
N
L
N
V
V
D
Site 45
Y522
V
V
D
G
R
L
T
Y
P
T
C
G
I
G
Y
Site 46
T524
D
G
R
L
T
Y
P
T
C
G
I
G
Y
P
V
Site 47
S544
F
Q
N
T
F
P
H
S
I
S
A
K
N
T
S
Site 48
T550
H
S
I
S
A
K
N
T
S
H
P
G
S
G
T
Site 49
S551
S
I
S
A
K
N
T
S
H
P
G
S
G
T
K
Site 50
S555
K
N
T
S
H
P
G
S
G
T
K
V
Q
F
N
Site 51
S571
Q
F
T
K
P
N
A
S
L
G
D
V
Q
S
G
Site 52
S582
V
Q
S
G
A
T
I
S
M
P
C
S
T
D
K
Site 53
S586
A
T
I
S
M
P
C
S
T
D
K
E
N
G
E
Site 54
Y601
N
V
G
L
E
S
K
Y
L
K
K
R
E
D
S
Site 55
S608
Y
L
K
K
R
E
D
S
I
P
L
R
G
L
S
Site 56
S615
S
I
P
L
R
G
L
S
Q
N
L
F
S
N
S
Site 57
S620
G
L
S
Q
N
L
F
S
N
S
D
H
Q
R
D
Site 58
S622
S
Q
N
L
F
S
N
S
D
H
Q
R
D
G
T
Site 59
T629
S
D
H
Q
R
D
G
T
L
G
A
L
H
T
S
Site 60
T635
G
T
L
G
A
L
H
T
S
S
K
P
T
A
L
Site 61
S637
L
G
A
L
H
T
S
S
K
P
T
A
L
P
S
Site 62
T640
L
H
T
S
S
K
P
T
A
L
P
S
A
S
S
Site 63
S644
S
K
P
T
A
L
P
S
A
S
S
A
Y
F
P
Site 64
S646
P
T
A
L
P
S
A
S
S
A
Y
F
P
G
Q
Site 65
S657
F
P
G
Q
L
P
N
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation