PhosphoNET

           
Protein Info 
   
Short Name:  FBXO46
Full Name:  F-box only protein 46
Alias:  20D7-FC4; F-box only protein 34-like; F-box protein 46; Fbx46; FBXO34L; FX46
Type:  Ubiquitin conjugating system
Mass (Da):  69031
Number AA:  646
UniProt ID:  Q6PJ61
International Prot ID:  IPI00419450
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:  GO:0019941     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y20CPRPFGTYSQNQPRP
Site 2S21PRPFGTYSQNQPRPP
Site 3S29QNQPRPPSAALKPSA
Site 4S35PSAALKPSACPEPGG
Site 5S53PDHGPAHSENTPPAL
Site 6T56GPAHSENTPPALATE
Site 7T62NTPPALATEVPASQP
Site 8S74SQPAPLLSAAAAGDE
Site 9T88EGRVLLDTWYVIKPG
Site 10Y90RVLLDTWYVIKPGNT
Site 11S113AHQCGGGSRASSMKV
Site 12S116CGGGSRASSMKVKGH
Site 13S117GGGSRASSMKVKGHW
Site 14S126KVKGHWGSDSSKAKR
Site 15S128KGHWGSDSSKAKRRR
Site 16S129GHWGSDSSKAKRRRR
Site 17T141RRRCLDPTKAPPDPG
Site 18S162AAEEGPASAGEDVDL
Site 19S189RAALALQSYPRPTTP
Site 20Y190AALALQSYPRPTTPA
Site 21T194LQSYPRPTTPAPVVF
Site 22T195QSYPRPTTPAPVVFV
Site 23S215GPAKGVGSERRSGGG
Site 24S219GVGSERRSGGGDCSR
Site 25S225RSGGGDCSRVAEAVA
Site 26S240HFEAQRDSPPTKGLR
Site 27S266VRIAFRISNGREPRA
Site 28S276REPRAPDSGLPSGGG
Site 29S280APDSGLPSGGGGRPG
Site 30Y290GGRPGCAYPGSPGPG
Site 31S293PGCAYPGSPGPGARA
Site 32Y309DKITCDLYQLISPSR
Site 33S313CDLYQLISPSRDALP
Site 34S315LYQLISPSRDALPSN
Site 35S334LARADEASEGDSPAP
Site 36S338DEASEGDSPAPARPE
Site 37T347APARPEDTPPAPPPP
Site 38T385IFFGKDGTKNVKEET
Site 39T392TKNVKEETVCLTVSP
Site 40T396KEETVCLTVSPEEPP
Site 41S398ETVCLTVSPEEPPPP
Site 42S427PEPPPADSPATAPGP
Site 43T440GPDDAEGTADTSLCR
Site 44S444AEGTADTSLCRLYRH
Site 45Y449DTSLCRLYRHVSHDF
Site 46S453CRLYRHVSHDFLEIR
Site 47Y472RLLEPRQYMLLLPEH
Site 48T515EAFGVRATDSRWSRD
Site 49S517FGVRATDSRWSRDPL
Site 50S520RATDSRWSRDPLYRD
Site 51Y525RWSRDPLYRDDPCKQ
Site 52Y537CKQCRKRYEKGDVSL
Site 53T573CRRADRETPGCRLGL
Site 54S604AGREEGRSTRGRGGE
Site 55T605GREEGRSTRGRGGES
Site 56S612TRGRGGESPPRPPLP
Site 57S620PPRPPLPSPPGSRGS
Site 58S624PLPSPPGSRGSGLGR
Site 59S627SPPGSRGSGLGRLPI
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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