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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SPSB3
Full Name:
SPRY domain-containing SOCS box protein 3
Alias:
C16orf31; SplA/ryanodine receptor domain and SOCS box containing 3; SPRY domain-containing SOCS box protein SSB-3; SSB3; SSB-3
Type:
Unknown function
Mass (Da):
39380
Number AA:
UniProt ID:
Q6PJ21
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007242
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
R
R
P
R
N
S
R
A
W
H
F
V
L
Site 2
S16
R
A
W
H
F
V
L
S
A
A
R
R
D
A
D
Site 3
Y37
A
G
S
T
N
W
G
Y
D
S
D
G
Q
H
S
Site 4
S39
S
T
N
W
G
Y
D
S
D
G
Q
H
S
D
S
Site 5
S44
Y
D
S
D
G
Q
H
S
D
S
D
S
D
P
E
Site 6
S46
S
D
G
Q
H
S
D
S
D
S
D
P
E
Y
S
Site 7
S48
G
Q
H
S
D
S
D
S
D
P
E
Y
S
T
L
Site 8
Y52
D
S
D
S
D
P
E
Y
S
T
L
P
P
S
I
Site 9
S53
S
D
S
D
P
E
Y
S
T
L
P
P
S
I
P
Site 10
T54
D
S
D
P
E
Y
S
T
L
P
P
S
I
P
S
Site 11
S80
C
A
G
Q
S
E
A
S
F
C
S
S
L
H
S
Site 12
S83
Q
S
E
A
S
F
C
S
S
L
H
S
A
H
R
Site 13
S84
S
E
A
S
F
C
S
S
L
H
S
A
H
R
G
Site 14
S87
S
F
C
S
S
L
H
S
A
H
R
G
R
D
C
Site 15
Y102
R
C
G
E
E
D
E
Y
F
D
W
V
W
D
D
Site 16
S113
V
W
D
D
L
N
K
S
S
A
T
L
L
S
C
Site 17
S114
W
D
D
L
N
K
S
S
A
T
L
L
S
C
D
Site 18
S119
K
S
S
A
T
L
L
S
C
D
N
R
K
V
S
Site 19
Y131
K
V
S
F
H
M
E
Y
S
C
G
T
A
A
I
Site 20
T141
G
T
A
A
I
R
G
T
K
E
L
G
E
G
Q
Site 21
T170
D
M
M
V
G
I
G
T
S
D
V
D
L
D
K
Site 22
Y178
S
D
V
D
L
D
K
Y
R
H
T
F
C
S
L
Site 23
T181
D
L
D
K
Y
R
H
T
F
C
S
L
L
G
R
Site 24
S184
K
Y
R
H
T
F
C
S
L
L
G
R
D
E
D
Site 25
S192
L
L
G
R
D
E
D
S
W
G
L
S
Y
T
G
Site 26
S196
D
E
D
S
W
G
L
S
Y
T
G
L
L
H
H
Site 27
T208
L
H
H
K
G
D
K
T
S
F
S
S
R
F
G
Site 28
S209
H
H
K
G
D
K
T
S
F
S
S
R
F
G
Q
Site 29
S211
K
G
D
K
T
S
F
S
S
R
F
G
Q
G
S
Site 30
S212
G
D
K
T
S
F
S
S
R
F
G
Q
G
S
I
Site 31
S218
S
S
R
F
G
Q
G
S
I
I
G
V
H
L
D
Site 32
T232
D
T
W
H
G
T
L
T
F
F
K
N
R
K
C
Site 33
Y253
K
L
Q
N
K
R
F
Y
P
M
V
C
S
T
A
Site 34
S258
R
F
Y
P
M
V
C
S
T
A
A
R
S
S
M
Site 35
T259
F
Y
P
M
V
C
S
T
A
A
R
S
S
M
K
Site 36
S264
C
S
T
A
A
R
S
S
M
K
V
T
R
S
C
Site 37
T268
A
R
S
S
M
K
V
T
R
S
C
A
S
A
T
Site 38
S270
S
S
M
K
V
T
R
S
C
A
S
A
T
S
L
Site 39
S273
K
V
T
R
S
C
A
S
A
T
S
L
Q
Y
L
Site 40
S292
L
R
Q
L
R
P
D
S
G
D
T
L
E
G
L
Site 41
T295
L
R
P
D
S
G
D
T
L
E
G
L
P
L
P
Site 42
S318
N
K
L
G
W
V
L
S
M
S
C
S
R
R
K
Site 43
S320
L
G
W
V
L
S
M
S
C
S
R
R
K
A
P
Site 44
S322
W
V
L
S
M
S
C
S
R
R
K
A
P
V
S
Site 45
S329
S
R
R
K
A
P
V
S
D
P
Q
A
A
T
S
Site 46
S336
S
D
P
Q
A
A
T
S
A
H
P
S
S
R
E
Site 47
S340
A
A
T
S
A
H
P
S
S
R
E
P
R
P
C
Site 48
S341
A
T
S
A
H
P
S
S
R
E
P
R
P
C
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation