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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KCTD18
Full Name:
BTB/POZ domain-containing protein KCTD18
Alias:
Type:
Mass (Da):
46739
Number AA:
426
UniProt ID:
Q6PI47
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y23
L
N
V
G
G
C
I
Y
T
A
R
R
E
S
L
Site 2
T24
N
V
G
G
C
I
Y
T
A
R
R
E
S
L
C
Site 3
S29
I
Y
T
A
R
R
E
S
L
C
R
F
K
D
S
Site 4
S40
F
K
D
S
M
L
A
S
M
F
S
G
R
F
P
Site 5
S43
S
M
L
A
S
M
F
S
G
R
F
P
L
K
T
Site 6
T50
S
G
R
F
P
L
K
T
D
E
S
G
A
C
V
Site 7
S53
F
P
L
K
T
D
E
S
G
A
C
V
I
D
R
Site 8
Y67
R
D
G
R
L
F
K
Y
L
L
D
Y
L
H
G
Site 9
Y94
A
L
Q
E
E
A
D
Y
F
G
I
P
Y
P
Y
Site 10
Y99
A
D
Y
F
G
I
P
Y
P
Y
S
L
S
D
H
Site 11
S102
F
G
I
P
Y
P
Y
S
L
S
D
H
L
A
N
Site 12
S104
I
P
Y
P
Y
S
L
S
D
H
L
A
N
E
M
Site 13
Y114
L
A
N
E
M
E
T
Y
S
L
R
S
N
I
E
Site 14
S115
A
N
E
M
E
T
Y
S
L
R
S
N
I
E
L
Site 15
T127
I
E
L
K
K
A
L
T
D
F
C
D
S
Y
G
Site 16
Y133
L
T
D
F
C
D
S
Y
G
L
V
C
N
K
P
Site 17
T150
W
V
L
H
Y
L
N
T
S
G
A
S
C
E
S
Site 18
S151
V
L
H
Y
L
N
T
S
G
A
S
C
E
S
R
Site 19
Y163
E
S
R
I
I
G
V
Y
A
T
K
T
D
G
T
Site 20
S183
Q
L
G
G
R
I
H
S
K
G
I
F
K
R
E
Site 21
Y197
E
A
G
N
N
V
Q
Y
I
W
S
Y
Y
S
V
Site 22
Y201
N
V
Q
Y
I
W
S
Y
Y
S
V
A
E
L
K
Site 23
Y202
V
Q
Y
I
W
S
Y
Y
S
V
A
E
L
K
K
Site 24
S223
A
W
E
G
K
G
V
S
Y
W
R
V
P
H
E
Site 25
Y224
W
E
G
K
G
V
S
Y
W
R
V
P
H
E
L
Site 26
T236
H
E
L
I
E
C
W
T
L
E
E
R
P
L
L
Site 27
S245
E
E
R
P
L
L
G
S
L
R
H
M
A
P
I
Site 28
T259
I
R
K
R
R
L
I
T
F
N
E
A
D
E
S
Site 29
S266
T
F
N
E
A
D
E
S
V
N
Y
K
T
G
P
Site 30
Y269
E
A
D
E
S
V
N
Y
K
T
G
P
K
P
V
Site 31
S282
P
V
R
F
L
G
P
S
T
S
T
Q
I
K
V
Site 32
S284
R
F
L
G
P
S
T
S
T
Q
I
K
V
K
N
Site 33
T305
S
P
A
S
A
I
Q
T
S
A
G
A
T
A
N
Site 34
T310
I
Q
T
S
A
G
A
T
A
N
R
F
Q
S
G
Site 35
S316
A
T
A
N
R
F
Q
S
G
S
R
R
K
A
A
Site 36
S318
A
N
R
F
Q
S
G
S
R
R
K
A
A
Q
R
Site 37
T332
R
S
A
P
S
R
A
T
A
L
V
G
T
G
A
Site 38
T337
R
A
T
A
L
V
G
T
G
A
P
G
H
P
Q
Site 39
S346
A
P
G
H
P
Q
A
S
P
G
A
A
S
A
E
Site 40
S351
Q
A
S
P
G
A
A
S
A
E
N
G
G
T
H
Site 41
T357
A
S
A
E
N
G
G
T
H
L
P
P
A
K
V
Site 42
S367
P
P
A
K
V
L
L
S
D
K
K
P
T
P
Q
Site 43
T372
L
L
S
D
K
K
P
T
P
Q
R
V
I
K
L
Site 44
S393
A
T
A
P
C
L
P
S
P
T
A
T
R
Q
A
Site 45
T397
C
L
P
S
P
T
A
T
R
Q
A
N
S
L
K
Site 46
S402
T
A
T
R
Q
A
N
S
L
K
P
L
P
G
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation