KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZCCHC12
Full Name:
Zinc finger CCHC domain-containing protein 12
Alias:
FLJ16123; SIZN; SIZN1; ZCH12; Zinc finger, CCHC domain containing 12
Type:
Unknown function
Mass (Da):
45369
Number AA:
402
UniProt ID:
Q6PEW1
International Prot ID:
IPI00166136
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
I
I
A
R
V
G
N
S
R
R
L
N
A
P
L
Site 2
S24
P
L
P
P
W
A
H
S
M
L
R
S
L
G
R
Site 3
S28
W
A
H
S
M
L
R
S
L
G
R
S
L
G
P
Site 4
S39
S
L
G
P
I
M
A
S
M
A
D
R
N
M
K
Site 5
S49
D
R
N
M
K
L
F
S
G
R
V
V
P
A
Q
Site 6
T60
V
P
A
Q
G
E
E
T
F
E
N
W
L
T
Q
Site 7
T66
E
T
F
E
N
W
L
T
Q
V
N
G
V
L
P
Site 8
S78
V
L
P
D
W
N
M
S
E
E
E
K
L
K
R
Site 9
T89
K
L
K
R
L
M
K
T
L
R
G
P
A
R
E
Site 10
S109
Q
A
T
N
P
N
L
S
V
A
D
F
L
R
A
Site 11
S124
M
K
L
V
F
G
E
S
E
S
S
V
T
A
H
Site 12
S127
V
F
G
E
S
E
S
S
V
T
A
H
G
K
F
Site 13
T129
G
E
S
E
S
S
V
T
A
H
G
K
F
F
N
Site 14
T137
A
H
G
K
F
F
N
T
L
Q
A
Q
G
E
K
Site 15
S146
Q
A
Q
G
E
K
A
S
L
Y
V
I
R
L
E
Site 16
Y148
Q
G
E
K
A
S
L
Y
V
I
R
L
E
V
Q
Site 17
S185
L
L
L
G
G
E
L
S
R
D
L
R
L
R
L
Site 18
Y199
L
K
D
F
L
R
M
Y
A
N
E
Q
E
R
L
Site 19
S235
K
R
K
R
P
K
R
S
E
S
M
V
E
R
A
Site 20
S237
K
R
P
K
R
S
E
S
M
V
E
R
A
V
S
Site 21
T269
N
V
I
E
I
D
D
T
L
D
D
S
D
E
D
Site 22
S273
I
D
D
T
L
D
D
S
D
E
D
V
I
L
V
Site 23
S282
E
D
V
I
L
V
E
S
Q
D
P
P
L
P
S
Site 24
S289
S
Q
D
P
P
L
P
S
W
G
A
P
P
L
R
Site 25
S310
D
E
V
L
V
I
D
S
P
H
N
S
R
A
Q
Site 26
S314
V
I
D
S
P
H
N
S
R
A
Q
F
P
S
T
Site 27
S320
N
S
R
A
Q
F
P
S
T
S
G
G
S
G
Y
Site 28
T321
S
R
A
Q
F
P
S
T
S
G
G
S
G
Y
K
Site 29
S322
R
A
Q
F
P
S
T
S
G
G
S
G
Y
K
N
Site 30
Y327
S
T
S
G
G
S
G
Y
K
N
N
G
P
G
E
Site 31
T344
R
A
R
K
R
K
H
T
I
R
C
S
Y
C
G
Site 32
Y349
K
H
T
I
R
C
S
Y
C
G
E
E
G
H
S
Site 33
S364
K
E
T
C
D
N
E
S
D
K
A
Q
V
F
E
Site 34
T383
T
L
Q
E
L
T
H
T
E
M
E
R
S
R
V
Site 35
S388
T
H
T
E
M
E
R
S
R
V
A
P
G
E
Y
Site 36
Y395
S
R
V
A
P
G
E
Y
N
D
F
S
E
P
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation