KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CNKSR3
Full Name:
Connector enhancer of kinase suppressor of ras 3
Alias:
CNKR3; CNKSR family member 3; MAGI1; Maguin-like protein; Membrane associated guanylate kinase interacting protein-like 1
Type:
Membrane, Cytoplasm protein
Mass (Da):
61904
Number AA:
555
UniProt ID:
Q6P9H4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0009966
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
E
P
V
T
K
W
S
P
K
Q
V
V
D
W
Site 2
Y26
L
D
D
C
L
Q
Q
Y
V
H
K
F
E
R
E
Site 3
S91
L
V
L
K
L
R
A
S
S
H
N
L
Q
N
Y
Site 4
S92
V
L
K
L
R
A
S
S
H
N
L
Q
N
Y
I
Site 5
Y98
S
S
H
N
L
Q
N
Y
I
S
S
R
R
K
S
Site 6
S100
H
N
L
Q
N
Y
I
S
S
R
R
K
S
P
A
Site 7
S101
N
L
Q
N
Y
I
S
S
R
R
K
S
P
A
Y
Site 8
S105
Y
I
S
S
R
R
K
S
P
A
Y
D
G
N
T
Site 9
Y108
S
R
R
K
S
P
A
Y
D
G
N
T
S
R
K
Site 10
T112
S
P
A
Y
D
G
N
T
S
R
K
A
P
N
E
Site 11
S113
P
A
Y
D
G
N
T
S
R
K
A
P
N
E
F
Site 12
S150
F
T
G
I
T
D
F
S
V
T
K
N
K
I
I
Site 13
T194
L
N
G
I
C
D
K
T
I
R
S
T
T
D
P
Site 14
S197
I
C
D
K
T
I
R
S
T
T
D
P
V
M
S
Site 15
T198
C
D
K
T
I
R
S
T
T
D
P
V
M
S
Q
Site 16
T199
D
K
T
I
R
S
T
T
D
P
V
M
S
Q
C
Site 17
S204
S
T
T
D
P
V
M
S
Q
C
A
C
L
E
E
Site 18
Y226
P
G
E
G
L
G
M
Y
I
K
S
T
Y
D
G
Site 19
T240
G
L
H
V
I
T
G
T
T
E
N
S
P
A
D
Site 20
S244
I
T
G
T
T
E
N
S
P
A
D
R
S
Q
K
Site 21
S249
E
N
S
P
A
D
R
S
Q
K
I
H
A
G
D
Site 22
T283
K
K
L
R
E
N
P
T
G
V
V
L
L
L
K
Site 23
T294
L
L
L
K
K
R
P
T
G
S
F
N
F
T
P
Site 24
S296
L
K
K
R
P
T
G
S
F
N
F
T
P
A
P
Site 25
T300
P
T
G
S
F
N
F
T
P
A
P
L
K
N
L
Site 26
S317
K
P
P
L
V
Q
T
S
P
P
P
A
T
T
Q
Site 27
T323
T
S
P
P
P
A
T
T
Q
S
P
E
S
T
M
Site 28
S325
P
P
P
A
T
T
Q
S
P
E
S
T
M
D
T
Site 29
S328
A
T
T
Q
S
P
E
S
T
M
D
T
S
L
K
Site 30
T329
T
T
Q
S
P
E
S
T
M
D
T
S
L
K
K
Site 31
T332
S
P
E
S
T
M
D
T
S
L
K
K
E
K
S
Site 32
S333
P
E
S
T
M
D
T
S
L
K
K
E
K
S
A
Site 33
S339
T
S
L
K
K
E
K
S
A
I
L
D
L
Y
I
Site 34
S355
P
P
P
A
V
P
Y
S
P
R
D
E
N
G
S
Site 35
S362
S
P
R
D
E
N
G
S
F
V
Y
G
G
S
S
Site 36
Y365
D
E
N
G
S
F
V
Y
G
G
S
S
K
C
K
Site 37
S369
S
F
V
Y
G
G
S
S
K
C
K
Q
P
L
P
Site 38
S381
P
L
P
G
P
K
G
S
E
S
P
N
S
F
L
Site 39
S383
P
G
P
K
G
S
E
S
P
N
S
F
L
D
Q
Site 40
S386
K
G
S
E
S
P
N
S
F
L
D
Q
E
S
R
Site 41
S392
N
S
F
L
D
Q
E
S
R
R
R
R
F
T
I
Site 42
T398
E
S
R
R
R
R
F
T
I
A
D
S
D
Q
L
Site 43
S402
R
R
F
T
I
A
D
S
D
Q
L
P
G
Y
S
Site 44
Y408
D
S
D
Q
L
P
G
Y
S
V
E
T
N
I
L
Site 45
S409
S
D
Q
L
P
G
Y
S
V
E
T
N
I
L
P
Site 46
T423
P
T
K
M
R
E
K
T
P
S
Y
G
K
P
R
Site 47
S425
K
M
R
E
K
T
P
S
Y
G
K
P
R
P
L
Site 48
Y426
M
R
E
K
T
P
S
Y
G
K
P
R
P
L
S
Site 49
S433
Y
G
K
P
R
P
L
S
M
P
A
D
G
N
W
Site 50
Y464
G
E
D
A
L
C
R
Y
F
S
N
E
R
I
P
Site 51
S466
D
A
L
C
R
Y
F
S
N
E
R
I
P
P
I
Site 52
S477
I
P
P
I
I
E
E
S
S
S
P
P
Y
R
F
Site 53
S478
P
P
I
I
E
E
S
S
S
P
P
Y
R
F
S
Site 54
S479
P
I
I
E
E
S
S
S
P
P
Y
R
F
S
R
Site 55
Y482
E
E
S
S
S
P
P
Y
R
F
S
R
P
T
T
Site 56
S485
S
S
P
P
Y
R
F
S
R
P
T
T
E
R
H
Site 57
T488
P
Y
R
F
S
R
P
T
T
E
R
H
L
V
R
Site 58
T489
Y
R
F
S
R
P
T
T
E
R
H
L
V
R
G
Site 59
Y499
H
L
V
R
G
A
D
Y
I
R
G
S
R
C
Y
Site 60
S503
G
A
D
Y
I
R
G
S
R
C
Y
I
N
S
D
Site 61
Y506
Y
I
R
G
S
R
C
Y
I
N
S
D
L
H
S
Site 62
S509
G
S
R
C
Y
I
N
S
D
L
H
S
S
A
T
Site 63
S513
Y
I
N
S
D
L
H
S
S
A
T
I
P
F
Q
Site 64
S528
E
E
G
T
K
K
K
S
G
S
S
A
T
K
S
Site 65
S530
G
T
K
K
K
S
G
S
S
A
T
K
S
S
S
Site 66
S531
T
K
K
K
S
G
S
S
A
T
K
S
S
S
T
Site 67
T533
K
K
S
G
S
S
A
T
K
S
S
S
T
E
P
Site 68
S535
S
G
S
S
A
T
K
S
S
S
T
E
P
S
L
Site 69
S536
G
S
S
A
T
K
S
S
S
T
E
P
S
L
L
Site 70
S537
S
S
A
T
K
S
S
S
T
E
P
S
L
L
V
Site 71
S541
K
S
S
S
T
E
P
S
L
L
V
S
W
F
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation