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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF449
Full Name:
Zinc finger protein 449
Alias:
Zinc finger and SCAN domain-containing protein 19
Type:
Mass (Da):
59932
Number AA:
518
UniProt ID:
Q6P9G9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y22
Q
G
S
V
F
Q
E
Y
D
T
D
C
E
V
F
Site 2
T24
S
V
F
Q
E
Y
D
T
D
C
E
V
F
R
Q
Site 3
S103
E
N
R
E
R
V
V
S
L
I
E
D
L
Q
R
Site 4
T140
G
T
A
H
I
P
P
T
M
H
L
E
S
P
A
Site 5
S145
P
P
T
M
H
L
E
S
P
A
L
Q
V
M
G
Site 6
Y174
A
G
P
P
E
L
N
Y
G
A
T
G
E
C
Q
Site 7
Y188
Q
N
F
L
D
P
G
Y
P
L
P
K
L
D
M
Site 8
S198
P
K
L
D
M
N
F
S
L
E
N
R
E
E
P
Site 9
S213
W
V
K
E
L
Q
D
S
K
E
M
K
Q
L
L
Site 10
S222
E
M
K
Q
L
L
D
S
K
I
G
F
E
I
G
Site 11
S237
I
E
N
E
E
D
T
S
K
Q
K
K
M
E
T
Site 12
T244
S
K
Q
K
K
M
E
T
M
Y
P
F
I
V
T
Site 13
Y246
Q
K
K
M
E
T
M
Y
P
F
I
V
T
L
E
Site 14
Y266
G
P
I
L
Q
K
D
Y
V
Q
L
E
N
Q
W
Site 15
T275
Q
L
E
N
Q
W
E
T
P
P
E
D
L
Q
T
Site 16
T282
T
P
P
E
D
L
Q
T
D
L
A
K
L
V
D
Site 17
T298
Q
N
P
T
L
G
E
T
P
E
N
S
N
L
E
Site 18
S302
L
G
E
T
P
E
N
S
N
L
E
E
P
L
N
Site 19
S317
P
K
P
H
K
K
K
S
P
G
E
K
P
H
R
Site 20
S336
G
K
C
F
A
R
K
S
Q
L
T
G
H
Q
R
Site 21
T339
F
A
R
K
S
Q
L
T
G
H
Q
R
I
H
S
Site 22
S346
T
G
H
Q
R
I
H
S
G
E
E
P
H
K
C
Site 23
S364
G
K
R
F
L
R
S
S
D
L
Y
R
H
Q
R
Site 24
Y367
F
L
R
S
S
D
L
Y
R
H
Q
R
L
H
T
Site 25
T374
Y
R
H
Q
R
L
H
T
G
E
R
P
Y
E
C
Site 26
Y379
L
H
T
G
E
R
P
Y
E
C
T
V
C
K
K
Site 27
T382
G
E
R
P
Y
E
C
T
V
C
K
K
R
F
T
Site 28
T389
T
V
C
K
K
R
F
T
R
R
S
H
L
I
G
Site 29
S392
K
K
R
F
T
R
R
S
H
L
I
G
H
Q
R
Site 30
S402
I
G
H
Q
R
T
H
S
E
E
E
T
Y
K
C
Site 31
T406
R
T
H
S
E
E
E
T
Y
K
C
L
E
C
G
Site 32
Y407
T
H
S
E
E
E
T
Y
K
C
L
E
C
G
K
Site 33
S415
K
C
L
E
C
G
K
S
F
C
H
G
S
S
L
Site 34
S420
G
K
S
F
C
H
G
S
S
L
K
R
H
L
K
Site 35
S421
K
S
F
C
H
G
S
S
L
K
R
H
L
K
T
Site 36
T428
S
L
K
R
H
L
K
T
H
T
G
E
K
P
H
Site 37
S443
R
C
H
N
C
G
K
S
F
S
R
L
T
A
L
Site 38
T448
G
K
S
F
S
R
L
T
A
L
T
L
H
Q
R
Site 39
T451
F
S
R
L
T
A
L
T
L
H
Q
R
T
H
T
Site 40
T458
T
L
H
Q
R
T
H
T
E
E
R
P
F
K
C
Site 41
Y467
E
R
P
F
K
C
N
Y
C
G
K
S
F
R
Q
Site 42
S477
K
S
F
R
Q
R
P
S
L
V
I
H
L
R
I
Site 43
T486
V
I
H
L
R
I
H
T
G
E
K
P
Y
K
C
Site 44
S499
K
C
T
H
C
S
K
S
F
R
Q
R
A
G
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation