KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
NOTUM
Full Name:
Protein notum homolog
Alias:
Type:
Mass (Da):
55699
Number AA:
496
UniProt ID:
Q6P988
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T25
G
G
S
E
G
R
K
T
W
R
R
R
G
Q
Q
Site 2
T57
E
S
F
P
L
D
F
T
A
V
E
G
N
M
D
Site 3
S65
A
V
E
G
N
M
D
S
F
M
A
Q
V
K
S
Site 4
S76
Q
V
K
S
L
A
Q
S
L
Y
P
C
S
A
Q
Site 5
Y78
K
S
L
A
Q
S
L
Y
P
C
S
A
Q
Q
L
Site 6
S81
A
Q
S
L
Y
P
C
S
A
Q
Q
L
N
E
D
Site 7
S105
S
V
T
C
N
D
G
S
P
A
G
Y
Y
L
K
Site 8
Y109
N
D
G
S
P
A
G
Y
Y
L
K
E
S
R
G
Site 9
Y110
D
G
S
P
A
G
Y
Y
L
K
E
S
R
G
S
Site 10
S117
Y
L
K
E
S
R
G
S
R
R
W
L
L
F
L
Site 11
Y140
R
E
N
C
D
S
R
Y
D
T
M
R
R
L
M
Site 12
T142
N
C
D
S
R
Y
D
T
M
R
R
L
M
S
S
Site 13
S148
D
T
M
R
R
L
M
S
S
R
D
W
P
R
T
Site 14
S149
T
M
R
R
L
M
S
S
R
D
W
P
R
T
R
Site 15
T155
S
S
R
D
W
P
R
T
R
T
G
T
G
I
L
Site 16
T157
R
D
W
P
R
T
R
T
G
T
G
I
L
S
S
Site 17
T159
W
P
R
T
R
T
G
T
G
I
L
S
S
Q
P
Site 18
S163
R
T
G
T
G
I
L
S
S
Q
P
E
E
N
P
Site 19
S164
T
G
T
G
I
L
S
S
Q
P
E
E
N
P
Y
Site 20
S189
Y
C
S
S
D
V
W
S
G
A
S
S
K
S
E
Site 21
S193
D
V
W
S
G
A
S
S
K
S
E
K
N
E
Y
Site 22
S195
W
S
G
A
S
S
K
S
E
K
N
E
Y
A
F
Site 23
Y200
S
K
S
E
K
N
E
Y
A
F
M
G
A
L
I
Site 24
Y254
E
Q
L
E
K
L
G
Y
P
A
I
Q
V
R
G
Site 25
S265
Q
V
R
G
L
A
D
S
G
W
F
L
D
N
K
Site 26
T277
D
N
K
Q
Y
R
H
T
D
C
V
D
T
I
T
Site 27
T282
R
H
T
D
C
V
D
T
I
T
C
A
P
T
E
Site 28
Y297
A
I
R
R
G
I
R
Y
W
N
G
V
V
P
E
Site 29
T352
T
V
D
N
V
H
L
T
G
Q
P
V
Q
E
G
Site 30
Y363
V
Q
E
G
L
R
L
Y
I
Q
N
L
G
R
E
Site 31
T374
L
G
R
E
L
R
H
T
L
K
D
V
P
A
S
Site 32
S388
S
F
A
P
A
C
L
S
H
E
I
I
I
R
S
Site 33
S406
D
V
Q
V
K
G
T
S
L
P
R
A
L
H
C
Site 34
S421
W
D
R
S
L
H
D
S
H
K
A
S
K
T
P
Site 35
S425
L
H
D
S
H
K
A
S
K
T
P
L
K
G
C
Site 36
T427
D
S
H
K
A
S
K
T
P
L
K
G
C
P
V
Site 37
T476
H
M
G
F
D
M
Q
T
V
A
Q
P
Q
G
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation