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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM54A
Full Name:
Protein FAM54A
Alias:
DUF729 domain-containing protein 1
Type:
Mass (Da):
43366
Number AA:
385
UniProt ID:
Q6P444
International Prot ID:
IPI00017979
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y31
L
I
W
E
N
K
D
Y
G
S
T
R
S
I
V
Site 2
S33
W
E
N
K
D
Y
G
S
T
R
S
I
V
R
I
Site 3
S36
K
D
Y
G
S
T
R
S
I
V
R
I
I
G
K
Site 4
S66
P
L
L
N
S
V
D
S
D
N
C
G
S
M
V
Site 5
S71
V
D
S
D
N
C
G
S
M
V
P
S
F
A
D
Site 6
Y81
P
S
F
A
D
I
L
Y
V
A
N
D
E
E
A
Site 7
S89
V
A
N
D
E
E
A
S
Y
L
R
F
R
N
S
Site 8
Y90
A
N
D
E
E
A
S
Y
L
R
F
R
N
S
I
Site 9
S96
S
Y
L
R
F
R
N
S
I
W
K
N
E
E
E
Site 10
S119
R
L
V
R
D
P
L
S
P
A
V
R
Q
K
E
Site 11
S154
N
E
L
T
F
L
R
S
Q
I
A
A
I
V
E
Site 12
S168
E
M
Q
E
L
K
N
S
T
N
S
S
S
F
G
Site 13
T169
M
Q
E
L
K
N
S
T
N
S
S
S
F
G
L
Site 14
S171
E
L
K
N
S
T
N
S
S
S
F
G
L
S
D
Site 15
S172
L
K
N
S
T
N
S
S
S
F
G
L
S
D
E
Site 16
S173
K
N
S
T
N
S
S
S
F
G
L
S
D
E
R
Site 17
S177
N
S
S
S
F
G
L
S
D
E
R
I
S
L
G
Site 18
S182
G
L
S
D
E
R
I
S
L
G
Q
L
S
S
S
Site 19
S187
R
I
S
L
G
Q
L
S
S
S
R
A
A
H
L
Site 20
S188
I
S
L
G
Q
L
S
S
S
R
A
A
H
L
S
Site 21
S189
S
L
G
Q
L
S
S
S
R
A
A
H
L
S
V
Site 22
S195
S
S
R
A
A
H
L
S
V
D
P
D
Q
L
P
Site 23
S204
D
P
D
Q
L
P
G
S
V
L
S
P
P
P
P
Site 24
S207
Q
L
P
G
S
V
L
S
P
P
P
P
P
P
L
Site 25
S219
P
P
L
P
P
Q
F
S
S
L
Q
P
P
C
F
Site 26
S220
P
L
P
P
Q
F
S
S
L
Q
P
P
C
F
P
Site 27
S233
F
P
P
V
Q
P
G
S
N
N
I
C
D
S
D
Site 28
S239
G
S
N
N
I
C
D
S
D
N
P
A
T
E
M
Site 29
T256
Q
N
P
A
A
N
K
T
N
Y
S
H
H
S
K
Site 30
Y258
P
A
A
N
K
T
N
Y
S
H
H
S
K
S
Q
Site 31
S259
A
A
N
K
T
N
Y
S
H
H
S
K
S
Q
R
Site 32
S264
N
Y
S
H
H
S
K
S
Q
R
N
K
D
I
P
Site 33
S291
K
L
R
A
I
E
R
S
P
G
G
R
P
I
H
Site 34
S305
H
K
R
K
R
Q
N
S
H
W
D
P
V
S
L
Site 35
S311
N
S
H
W
D
P
V
S
L
I
S
H
A
L
K
Site 36
S328
F
A
F
Q
E
D
D
S
F
E
K
E
N
R
S
Site 37
S335
S
F
E
K
E
N
R
S
W
E
S
S
P
F
S
Site 38
S338
K
E
N
R
S
W
E
S
S
P
F
S
S
P
E
Site 39
S339
E
N
R
S
W
E
S
S
P
F
S
S
P
E
T
Site 40
S342
S
W
E
S
S
P
F
S
S
P
E
T
S
R
F
Site 41
S343
W
E
S
S
P
F
S
S
P
E
T
S
R
F
G
Site 42
T346
S
P
F
S
S
P
E
T
S
R
F
G
H
H
I
Site 43
S347
P
F
S
S
P
E
T
S
R
F
G
H
H
I
S
Site 44
S354
S
R
F
G
H
H
I
S
Q
S
E
G
Q
R
T
Site 45
S356
F
G
H
H
I
S
Q
S
E
G
Q
R
T
K
E
Site 46
T361
S
Q
S
E
G
Q
R
T
K
E
E
M
V
N
T
Site 47
T368
T
K
E
E
M
V
N
T
K
A
V
D
Q
G
I
Site 48
S376
K
A
V
D
Q
G
I
S
N
T
S
L
L
N
S
Site 49
S379
D
Q
G
I
S
N
T
S
L
L
N
S
R
I
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation