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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
METTL2B
Full Name:
Methyltransferase-like protein 2B
Alias:
Type:
Mass (Da):
43440
Number AA:
378
UniProt ID:
Q6P1Q9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0008168
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
D
K
R
Q
Q
F
G
S
R
F
L
S
D
P
A
Site 2
S26
Q
F
G
S
R
F
L
S
D
P
A
R
V
F
H
Site 3
Y70
C
Q
E
K
Q
V
D
Y
E
I
N
A
H
K
Y
Site 4
T98
K
D
R
H
W
L
F
T
E
F
P
E
L
A
P
Site 5
S106
E
F
P
E
L
A
P
S
Q
N
Q
N
H
L
K
Site 6
S147
Q
H
K
C
S
S
K
S
L
E
H
K
T
Q
T
Site 7
T152
S
K
S
L
E
H
K
T
Q
T
P
P
V
E
E
Site 8
T154
S
L
E
H
K
T
Q
T
P
P
V
E
E
N
V
Site 9
T162
P
P
V
E
E
N
V
T
Q
K
I
S
D
L
E
Site 10
S166
E
N
V
T
Q
K
I
S
D
L
E
I
C
A
D
Site 11
S178
C
A
D
E
F
P
G
S
S
A
T
Y
R
I
L
Site 12
T181
E
F
P
G
S
S
A
T
Y
R
I
L
E
V
G
Site 13
T224
T
A
I
E
L
V
Q
T
N
S
E
Y
D
P
S
Site 14
S226
I
E
L
V
Q
T
N
S
E
Y
D
P
S
R
C
Site 15
Y228
L
V
Q
T
N
S
E
Y
D
P
S
R
C
F
A
Site 16
Y247
L
C
D
E
E
K
S
Y
P
V
P
K
G
S
L
Site 17
S279
Q
K
A
I
N
R
L
S
R
L
L
K
P
G
G
Site 18
Y293
G
M
V
L
L
R
D
Y
G
R
Y
D
M
A
Q
Site 19
Y296
L
L
R
D
Y
G
R
Y
D
M
A
Q
L
R
F
Site 20
Y314
Q
C
L
S
G
N
F
Y
V
R
G
D
G
T
R
Site 21
Y323
R
G
D
G
T
R
V
Y
F
F
T
Q
E
E
L
Site 22
T326
G
T
R
V
Y
F
F
T
Q
E
E
L
D
T
L
Site 23
Y361
R
G
K
Q
L
T
M
Y
R
V
W
I
Q
C
K
Site 24
Y369
R
V
W
I
Q
C
K
Y
C
K
P
L
L
S
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation