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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CC2D1A
Full Name:
Coiled-coil and C2 domain-containing protein 1A
Alias:
C2D1A; Coiled-coil and C2 domain containing 1A; Five repressor element under dual repression-binding protein 1; FLJ20241; FRE under dual repression-binding protein 1; Freud-1; Mental retardation, nonsyndromic, autosomal recessive, 3; MRT3; NF-kappa-B-activating protein 023N
Type:
Transcription factor
Mass (Da):
104062
Number AA:
951
UniProt ID:
Q6P1N0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0043123
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S78
E
A
I
E
K
M
A
S
L
C
M
R
D
P
D
Site 2
T92
D
E
D
E
E
E
G
T
D
E
D
D
L
E
A
Site 3
S118
L
G
E
E
Q
K
A
S
E
T
P
P
P
V
A
Site 4
T120
E
E
Q
K
A
S
E
T
P
P
P
V
A
Q
P
Site 5
T139
P
H
P
G
L
E
T
T
L
Q
E
R
L
A
L
Site 6
Y147
L
Q
E
R
L
A
L
Y
Q
T
A
I
E
S
A
Site 7
T149
E
R
L
A
L
Y
Q
T
A
I
E
S
A
R
Q
Site 8
S153
L
Y
Q
T
A
I
E
S
A
R
Q
A
G
D
S
Site 9
S160
S
A
R
Q
A
G
D
S
A
K
M
R
R
Y
D
Site 10
Y166
D
S
A
K
M
R
R
Y
D
R
G
L
K
T
L
Site 11
T172
R
Y
D
R
G
L
K
T
L
E
N
L
L
A
S
Site 12
S179
T
L
E
N
L
L
A
S
I
R
K
G
N
A
I
Site 13
S203
A
I
G
K
G
P
A
S
T
P
T
Y
S
P
A
Site 14
T204
I
G
K
G
P
A
S
T
P
T
Y
S
P
A
P
Site 15
T206
K
G
P
A
S
T
P
T
Y
S
P
A
P
T
Q
Site 16
Y207
G
P
A
S
T
P
T
Y
S
P
A
P
T
Q
P
Site 17
S208
P
A
S
T
P
T
Y
S
P
A
P
T
Q
P
A
Site 18
T212
P
T
Y
S
P
A
P
T
Q
P
A
P
R
I
A
Site 19
S220
Q
P
A
P
R
I
A
S
A
P
E
P
R
V
T
Site 20
T227
S
A
P
E
P
R
V
T
L
E
G
P
S
A
T
Site 21
T234
T
L
E
G
P
S
A
T
A
P
A
S
S
P
G
Site 22
S238
P
S
A
T
A
P
A
S
S
P
G
L
A
K
P
Site 23
S239
S
A
T
A
P
A
S
S
P
G
L
A
K
P
Q
Site 24
S253
Q
M
P
P
G
P
C
S
P
G
P
L
A
Q
L
Site 25
S262
G
P
L
A
Q
L
Q
S
R
Q
R
D
Y
K
L
Site 26
Y267
L
Q
S
R
Q
R
D
Y
K
L
A
A
L
H
A
Site 27
T281
A
K
Q
Q
G
D
T
T
A
A
A
R
H
F
R
Site 28
S292
R
H
F
R
V
A
K
S
F
D
A
V
L
E
A
Site 29
S309
R
G
E
P
V
D
L
S
C
L
P
P
P
P
D
Site 30
S324
Q
L
P
P
D
P
P
S
P
P
S
Q
P
P
T
Site 31
S327
P
D
P
P
S
P
P
S
Q
P
P
T
P
A
T
Site 32
T331
S
P
P
S
Q
P
P
T
P
A
T
A
P
S
T
Site 33
T334
S
Q
P
P
T
P
A
T
A
P
S
T
T
E
V
Site 34
S337
P
T
P
A
T
A
P
S
T
T
E
V
P
P
P
Site 35
T338
T
P
A
T
A
P
S
T
T
E
V
P
P
P
P
Site 36
T339
P
A
T
A
P
S
T
T
E
V
P
P
P
P
R
Site 37
T347
E
V
P
P
P
P
R
T
L
L
E
A
L
E
Q
Site 38
Y385
H
E
R
I
V
K
Q
Y
Q
D
A
I
R
A
H
Site 39
S424
A
T
K
P
T
Q
Q
S
L
V
G
V
L
E
T
Site 40
S455
E
V
P
K
K
Q
N
S
P
V
A
P
T
A
Q
Site 41
S468
A
Q
P
K
A
P
P
S
R
T
P
Q
S
G
S
Site 42
T470
P
K
A
P
P
S
R
T
P
Q
S
G
S
A
P
Site 43
S473
P
P
S
R
T
P
Q
S
G
S
A
P
T
A
K
Site 44
S475
S
R
T
P
Q
S
G
S
A
P
T
A
K
A
P
Site 45
S487
K
A
P
P
K
A
T
S
T
R
A
Q
Q
Q
L
Site 46
S569
Q
R
P
G
P
G
L
S
Q
E
A
A
R
R
Y
Site 47
Y576
S
Q
E
A
A
R
R
Y
G
E
L
T
K
L
I
Site 48
T580
A
R
R
Y
G
E
L
T
K
L
I
R
Q
Q
H
Site 49
T598
L
N
H
S
N
Q
F
T
Q
L
G
N
I
T
E
Site 50
T633
A
F
V
R
G
L
P
T
P
T
A
R
F
E
Q
Site 51
T642
T
A
R
F
E
Q
R
T
F
S
V
I
K
I
F
Site 52
S644
R
F
E
Q
R
T
F
S
V
I
K
I
F
P
D
Site 53
T669
V
K
G
I
N
L
P
T
P
P
G
L
S
P
G
Site 54
Y688
F
V
R
F
D
F
P
Y
P
N
V
E
E
A
Q
Site 55
T699
E
E
A
Q
K
D
K
T
S
V
I
K
N
T
D
Site 56
S700
E
A
Q
K
D
K
T
S
V
I
K
N
T
D
S
Site 57
T705
K
T
S
V
I
K
N
T
D
S
P
E
F
K
E
Site 58
S707
S
V
I
K
N
T
D
S
P
E
F
K
E
Q
F
Site 59
T731
G
F
R
R
A
I
Q
T
K
G
I
K
F
E
V
Site 60
T747
H
K
G
G
L
F
K
T
D
R
V
L
G
T
A
Site 61
T780
V
L
D
G
R
R
P
T
G
G
R
L
E
V
M
Site 62
S837
V
P
A
P
A
R
E
S
G
N
R
S
A
R
P
Site 63
S841
A
R
E
S
G
N
R
S
A
R
P
L
H
S
L
Site 64
S847
R
S
A
R
P
L
H
S
L
S
V
L
A
F
D
Site 65
S849
A
R
P
L
H
S
L
S
V
L
A
F
D
Q
E
Site 66
Y905
G
V
G
I
R
R
E
Y
A
A
Q
L
E
R
Q
Site 67
Y916
L
E
R
Q
L
Q
F
Y
T
E
A
A
R
R
L
Site 68
S928
R
R
L
G
N
D
G
S
R
D
A
A
K
E
A
Site 69
Y937
D
A
A
K
E
A
L
Y
R
R
N
L
V
E
S
Site 70
S944
Y
R
R
N
L
V
E
S
E
L
Q
R
L
R
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation