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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA1949
Full Name:
Phostensin
Alias:
PHTNS; Protein phosphatase 1 F-actin cytoskeleton-targeting subunit
Type:
Mass (Da):
67943
Number AA:
613
UniProt ID:
Q6NYC8
International Prot ID:
IPI00152853
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
Uniprot
OncoNet
Molecular Function:
GO:0003779
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
R
R
R
Q
E
E
A
S
V
R
G
R
E
K
A
Site 2
S34
K
A
E
R
E
R
L
S
Q
M
P
A
W
K
R
Site 3
S54
R
R
A
K
L
G
L
S
P
G
E
P
S
P
V
Site 4
S59
G
L
S
P
G
E
P
S
P
V
L
G
T
V
E
Site 5
T64
E
P
S
P
V
L
G
T
V
E
A
G
P
P
D
Site 6
S75
G
P
P
D
P
D
E
S
A
V
L
L
E
A
I
Site 7
S125
E
A
R
E
R
R
P
S
P
G
E
M
R
D
Q
Site 8
S133
P
G
E
M
R
D
Q
S
P
K
G
R
E
S
R
Site 9
S139
Q
S
P
K
G
R
E
S
R
E
E
R
L
S
P
Site 10
S145
E
S
R
E
E
R
L
S
P
R
E
T
R
E
R
Site 11
T149
E
R
L
S
P
R
E
T
R
E
R
R
L
G
I
Site 12
S163
I
G
G
A
Q
E
L
S
L
R
P
L
E
A
R
Site 13
S175
E
A
R
D
W
R
Q
S
P
G
E
V
G
D
R
Site 14
S183
P
G
E
V
G
D
R
S
S
R
L
S
E
A
W
Site 15
S184
G
E
V
G
D
R
S
S
R
L
S
E
A
W
K
Site 16
S187
G
D
R
S
S
R
L
S
E
A
W
K
W
R
L
Site 17
S195
E
A
W
K
W
R
L
S
P
G
E
T
P
E
R
Site 18
T199
W
R
L
S
P
G
E
T
P
E
R
S
L
R
L
Site 19
S203
P
G
E
T
P
E
R
S
L
R
L
A
E
S
R
Site 20
S209
R
S
L
R
L
A
E
S
R
E
Q
S
P
R
R
Site 21
S213
L
A
E
S
R
E
Q
S
P
R
R
K
E
V
E
Site 22
S221
P
R
R
K
E
V
E
S
R
L
S
P
G
E
S
Site 23
S224
K
E
V
E
S
R
L
S
P
G
E
S
A
Y
Q
Site 24
S228
S
R
L
S
P
G
E
S
A
Y
Q
K
L
G
L
Site 25
Y230
L
S
P
G
E
S
A
Y
Q
K
L
G
L
T
E
Site 26
S245
A
H
K
W
R
P
D
S
R
E
S
Q
E
Q
S
Site 27
S248
W
R
P
D
S
R
E
S
Q
E
Q
S
L
V
Q
Site 28
S252
S
R
E
S
Q
E
Q
S
L
V
Q
L
E
A
T
Site 29
T259
S
L
V
Q
L
E
A
T
E
W
R
L
R
S
G
Site 30
S265
A
T
E
W
R
L
R
S
G
E
E
R
Q
D
Y
Site 31
Y272
S
G
E
E
R
Q
D
Y
S
E
E
C
G
R
K
Site 32
S273
G
E
E
R
Q
D
Y
S
E
E
C
G
R
K
E
Site 33
S296
P
K
E
T
A
E
L
S
E
T
L
T
R
E
A
Site 34
T298
E
T
A
E
L
S
E
T
L
T
R
E
A
Q
G
Site 35
T300
A
E
L
S
E
T
L
T
R
E
A
Q
G
N
S
Site 36
T329
G
E
R
G
M
K
P
T
E
G
W
K
W
T
L
Site 37
T345
S
G
K
A
R
E
W
T
P
R
D
I
E
A
Q
Site 38
T353
P
R
D
I
E
A
Q
T
Q
K
P
E
P
P
E
Site 39
S361
Q
K
P
E
P
P
E
S
A
E
K
L
L
E
S
Site 40
S368
S
A
E
K
L
L
E
S
P
G
V
E
A
G
E
Site 41
S398
R
A
L
Q
N
C
C
S
V
P
S
P
L
P
P
Site 42
S401
Q
N
C
C
S
V
P
S
P
L
P
P
E
D
A
Site 43
T410
L
P
P
E
D
A
G
T
G
G
L
R
Q
Q
E
Site 44
S432
P
P
P
P
A
P
L
S
P
P
P
P
A
P
T
Site 45
T439
S
P
P
P
P
A
P
T
A
P
Q
P
P
G
D
Site 46
Y454
P
L
M
S
R
L
F
Y
G
V
K
A
G
P
G
Site 47
S468
G
V
G
A
P
R
R
S
G
H
T
F
T
V
N
Site 48
T471
A
P
R
R
S
G
H
T
F
T
V
N
P
R
R
Site 49
T473
R
R
S
G
H
T
F
T
V
N
P
R
R
S
V
Site 50
S479
F
T
V
N
P
R
R
S
V
P
P
A
T
P
A
Site 51
T484
R
R
S
V
P
P
A
T
P
A
T
P
T
S
P
Site 52
T487
V
P
P
A
T
P
A
T
P
T
S
P
A
T
V
Site 53
T489
P
A
T
P
A
T
P
T
S
P
A
T
V
D
A
Site 54
S490
A
T
P
A
T
P
T
S
P
A
T
V
D
A
A
Site 55
T493
A
T
P
T
S
P
A
T
V
D
A
A
V
P
G
Site 56
Y506
P
G
A
G
K
K
R
Y
P
T
A
E
E
I
L
Site 57
T508
A
G
K
K
R
Y
P
T
A
E
E
I
L
V
L
Site 58
S524
G
Y
L
R
L
S
R
S
C
L
A
K
G
S
P
Site 59
S530
R
S
C
L
A
K
G
S
P
E
R
H
H
K
Q
Site 60
S541
H
H
K
Q
L
K
I
S
F
S
E
T
A
L
E
Site 61
S543
K
Q
L
K
I
S
F
S
E
T
A
L
E
T
T
Site 62
T545
L
K
I
S
F
S
E
T
A
L
E
T
T
Y
Q
Site 63
Y551
E
T
A
L
E
T
T
Y
Q
Y
P
S
E
S
S
Site 64
Y553
A
L
E
T
T
Y
Q
Y
P
S
E
S
S
V
L
Site 65
S555
E
T
T
Y
Q
Y
P
S
E
S
S
V
L
E
E
Site 66
S558
Y
Q
Y
P
S
E
S
S
V
L
E
E
L
G
P
Site 67
S571
G
P
E
P
E
V
P
S
A
P
N
P
P
A
A
Site 68
S610
K
A
L
I
V
D
E
S
C
R
R
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation