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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF544
Full Name:
Zinc finger protein 544
Alias:
Zinc finger protein AF020591
Type:
Mass (Da):
81742
Number AA:
715
UniProt ID:
Q6NX49
International Prot ID:
IPI00004482
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y39
D
L
A
Q
R
T
L
Y
R
E
V
T
L
E
T
Site 2
T43
R
T
L
Y
R
E
V
T
L
E
T
W
E
H
I
Site 3
S64
L
S
K
S
D
V
I
S
Q
L
E
Q
E
E
D
Site 4
T86
A
P
R
D
W
K
A
T
L
E
E
N
R
L
N
Site 5
S94
L
E
E
N
R
L
N
S
E
K
D
R
A
R
E
Site 6
S104
D
R
A
R
E
E
L
S
H
H
V
E
V
Y
R
Site 7
S112
H
H
V
E
V
Y
R
S
G
P
E
E
P
P
S
Site 8
S119
S
G
P
E
E
P
P
S
L
V
L
G
K
V
Q
Site 9
S129
L
G
K
V
Q
D
Q
S
N
Q
L
R
E
H
Q
Site 10
S139
L
R
E
H
Q
E
N
S
L
R
F
M
V
L
T
Site 11
Y165
E
L
E
L
G
G
G
Y
S
L
P
S
T
L
S
Site 12
S181
L
P
T
T
L
P
T
S
T
G
F
P
K
P
N
Site 13
T182
P
T
T
L
P
T
S
T
G
F
P
K
P
N
S
Site 14
S189
T
G
F
P
K
P
N
S
Q
V
K
E
L
K
Q
Site 15
T236
S
K
L
G
N
V
E
T
G
K
K
N
P
Y
E
Site 16
Y242
E
T
G
K
K
N
P
Y
E
Y
I
V
S
G
D
Site 17
Y244
G
K
K
N
P
Y
E
Y
I
V
S
G
D
S
L
Site 18
S247
N
P
Y
E
Y
I
V
S
G
D
S
L
N
Y
G
Site 19
S250
E
Y
I
V
S
G
D
S
L
N
Y
G
S
S
L
Site 20
Y253
V
S
G
D
S
L
N
Y
G
S
S
L
C
F
H
Site 21
S255
G
D
S
L
N
Y
G
S
S
L
C
F
H
G
R
Site 22
S256
D
S
L
N
Y
G
S
S
L
C
F
H
G
R
T
Site 23
T263
S
L
C
F
H
G
R
T
F
S
V
K
K
S
D
Site 24
S265
C
F
H
G
R
T
F
S
V
K
K
S
D
D
C
Site 25
S269
R
T
F
S
V
K
K
S
D
D
C
K
D
Y
G
Site 26
Y275
K
S
D
D
C
K
D
Y
G
N
L
F
S
H
S
Site 27
S280
K
D
Y
G
N
L
F
S
H
S
V
S
L
N
E
Site 28
S282
Y
G
N
L
F
S
H
S
V
S
L
N
E
Q
K
Site 29
S284
N
L
F
S
H
S
V
S
L
N
E
Q
K
P
V
Site 30
Y298
V
H
F
G
K
S
Q
Y
E
C
D
E
C
R
E
Site 31
T306
E
C
D
E
C
R
E
T
C
S
E
S
L
C
L
Site 32
S310
C
R
E
T
C
S
E
S
L
C
L
V
Q
T
E
Site 33
T316
E
S
L
C
L
V
Q
T
E
R
S
G
P
G
E
Site 34
S319
C
L
V
Q
T
E
R
S
G
P
G
E
T
P
F
Site 35
T324
E
R
S
G
P
G
E
T
P
F
R
C
E
E
R
Site 36
T373
C
K
L
I
H
Q
R
T
H
T
G
E
K
P
F
Site 37
T375
L
I
H
Q
R
T
H
T
G
E
K
P
F
E
C
Site 38
T383
G
E
K
P
F
E
C
T
Q
C
G
K
S
F
S
Site 39
S388
E
C
T
Q
C
G
K
S
F
S
Q
S
Y
D
L
Site 40
S390
T
Q
C
G
K
S
F
S
Q
S
Y
D
L
V
I
Site 41
S392
C
G
K
S
F
S
Q
S
Y
D
L
V
I
H
Q
Site 42
Y393
G
K
S
F
S
Q
S
Y
D
L
V
I
H
Q
R
Site 43
T401
D
L
V
I
H
Q
R
T
H
T
G
E
K
P
Y
Site 44
T403
V
I
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 45
Y408
T
H
T
G
E
K
P
Y
E
C
D
L
C
G
K
Site 46
S416
E
C
D
L
C
G
K
S
F
T
Q
R
S
K
L
Site 47
T418
D
L
C
G
K
S
F
T
Q
R
S
K
L
I
T
Site 48
S421
G
K
S
F
T
Q
R
S
K
L
I
T
H
Q
R
Site 49
T425
T
Q
R
S
K
L
I
T
H
Q
R
I
H
T
G
Site 50
T431
I
T
H
Q
R
I
H
T
G
E
K
P
Y
Q
C
Site 51
Y436
I
H
T
G
E
K
P
Y
Q
C
I
E
C
R
K
Site 52
S449
R
K
S
F
R
W
N
S
N
L
I
V
H
Q
R
Site 53
T459
I
V
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 54
Y464
I
H
T
G
E
K
P
Y
E
C
T
H
C
G
K
Site 55
T467
G
E
K
P
Y
E
C
T
H
C
G
K
S
F
S
Site 56
S472
E
C
T
H
C
G
K
S
F
S
Q
S
Y
E
L
Site 57
S474
T
H
C
G
K
S
F
S
Q
S
Y
E
L
V
T
Site 58
S476
C
G
K
S
F
S
Q
S
Y
E
L
V
T
H
K
Site 59
T485
E
L
V
T
H
K
R
T
H
T
G
E
K
P
F
Site 60
T487
V
T
H
K
R
T
H
T
G
E
K
P
F
K
C
Site 61
T495
G
E
K
P
F
K
C
T
Q
C
G
K
S
F
S
Site 62
S502
T
Q
C
G
K
S
F
S
Q
K
Y
D
L
V
V
Site 63
Y505
G
K
S
F
S
Q
K
Y
D
L
V
V
H
Q
R
Site 64
T513
D
L
V
V
H
Q
R
T
H
T
G
E
K
P
Y
Site 65
T515
V
V
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 66
Y520
T
H
T
G
E
K
P
Y
E
C
N
L
C
G
K
Site 67
S528
E
C
N
L
C
G
K
S
F
S
Q
S
S
K
L
Site 68
S530
N
L
C
G
K
S
F
S
Q
S
S
K
L
I
T
Site 69
S532
C
G
K
S
F
S
Q
S
S
K
L
I
T
H
Q
Site 70
T537
S
Q
S
S
K
L
I
T
H
Q
R
I
H
T
G
Site 71
Y548
I
H
T
G
E
K
P
Y
Q
C
I
E
C
G
K
Site 72
S561
G
K
S
F
R
W
N
S
N
L
V
I
H
Q
R
Site 73
T571
V
I
H
Q
R
I
H
T
G
E
K
P
Y
D
C
Site 74
Y576
I
H
T
G
E
K
P
Y
D
C
T
H
C
G
K
Site 75
T579
G
E
K
P
Y
D
C
T
H
C
G
K
S
F
S
Site 76
S586
T
H
C
G
K
S
F
S
Q
S
Y
Q
L
V
A
Site 77
S588
C
G
K
S
F
S
Q
S
Y
Q
L
V
A
H
K
Site 78
T597
Q
L
V
A
H
K
R
T
H
T
G
E
K
P
Y
Site 79
T599
V
A
H
K
R
T
H
T
G
E
K
P
Y
E
C
Site 80
Y604
T
H
T
G
E
K
P
Y
E
C
N
E
C
G
K
Site 81
S616
C
G
K
A
F
N
R
S
T
Q
L
I
R
H
L
Site 82
T617
G
K
A
F
N
R
S
T
Q
L
I
R
H
L
Q
Site 83
T627
I
R
H
L
Q
I
H
T
G
E
K
P
Y
K
C
Site 84
S645
N
K
A
F
A
R
S
S
Y
L
V
M
H
Q
R
Site 85
Y646
K
A
F
A
R
S
S
Y
L
V
M
H
Q
R
T
Site 86
T653
Y
L
V
M
H
Q
R
T
H
T
G
E
K
P
F
Site 87
T655
V
M
H
Q
R
T
H
T
G
E
K
P
F
E
C
Site 88
S663
G
E
K
P
F
E
C
S
Q
C
G
K
A
F
S
Site 89
S670
S
Q
C
G
K
A
F
S
G
S
S
N
L
L
S
Site 90
S672
C
G
K
A
F
S
G
S
S
N
L
L
S
H
H
Site 91
S673
G
K
A
F
S
G
S
S
N
L
L
S
H
H
R
Site 92
S677
S
G
S
S
N
L
L
S
H
H
R
I
H
S
G
Site 93
S683
L
S
H
H
R
I
H
S
G
E
K
P
Y
E
C
Site 94
Y688
I
H
S
G
E
K
P
Y
E
C
S
D
C
G
K
Site 95
S691
G
E
K
P
Y
E
C
S
D
C
G
K
S
F
R
Site 96
S696
E
C
S
D
C
G
K
S
F
R
Q
Q
S
Q
L
Site 97
S701
G
K
S
F
R
Q
Q
S
Q
L
V
V
H
R
R
Site 98
T709
Q
L
V
V
H
R
R
T
H
T
G
E
K
P
_
Site 99
T711
V
V
H
R
R
T
H
T
G
E
K
P
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation