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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TMEM214
Full Name:
Transmembrane protein 214
Alias:
cDNA, FLJ96404
Type:
Mass (Da):
77133
Number AA:
689
UniProt ID:
Q6NUQ4
International Prot ID:
IPI00477118
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016020
GO:0016021
GO:0031224
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y47
E
A
N
G
V
W
K
Y
D
L
T
P
A
I
Q
Site 2
T50
G
V
W
K
Y
D
L
T
P
A
I
Q
T
T
S
Site 3
T56
L
T
P
A
I
Q
T
T
S
T
L
Y
E
R
G
Site 4
S57
T
P
A
I
Q
T
T
S
T
L
Y
E
R
G
F
Site 5
T58
P
A
I
Q
T
T
S
T
L
Y
E
R
G
F
E
Site 6
Y60
I
Q
T
T
S
T
L
Y
E
R
G
F
E
N
I
Site 7
T97
K
Q
P
K
K
V
A
T
P
P
N
Q
N
Q
K
Site 8
S110
Q
K
Q
G
R
F
R
S
L
E
E
A
L
K
A
Site 9
S130
L
Q
K
E
L
D
K
S
Q
S
V
F
S
G
N
Site 10
S132
K
E
L
D
K
S
Q
S
V
F
S
G
N
P
S
Site 11
S135
D
K
S
Q
S
V
F
S
G
N
P
S
I
W
L
Site 12
Y151
D
L
A
S
Y
L
N
Y
K
L
Q
A
P
L
S
Site 13
S158
Y
K
L
Q
A
P
L
S
E
P
T
L
S
Q
H
Site 14
T161
Q
A
P
L
S
E
P
T
L
S
Q
H
T
H
D
Site 15
S163
P
L
S
E
P
T
L
S
Q
H
T
H
D
Y
P
Site 16
Y169
L
S
Q
H
T
H
D
Y
P
Y
S
L
V
S
R
Site 17
Y171
Q
H
T
H
D
Y
P
Y
S
L
V
S
R
E
L
Site 18
S172
H
T
H
D
Y
P
Y
S
L
V
S
R
E
L
R
Site 19
T211
M
L
Q
E
L
D
K
T
P
G
E
S
L
H
G
Site 20
S247
K
F
L
E
L
L
R
S
H
Q
S
R
P
A
K
Site 21
S250
E
L
L
R
S
H
Q
S
R
P
A
K
C
L
T
Site 22
S333
F
A
Y
M
P
N
N
S
L
T
P
S
L
Q
E
Site 23
T335
Y
M
P
N
N
S
L
T
P
S
L
Q
E
Q
L
Site 24
S337
P
N
N
S
L
T
P
S
L
Q
E
Q
L
C
Q
Site 25
Y346
Q
E
Q
L
C
Q
L
Y
P
R
L
K
V
L
A
Site 26
S360
A
F
G
A
K
P
D
S
T
L
H
T
Y
F
P
Site 27
T361
F
G
A
K
P
D
S
T
L
H
T
Y
F
P
S
Site 28
T364
K
P
D
S
T
L
H
T
Y
F
P
S
F
L
S
Site 29
Y365
P
D
S
T
L
H
T
Y
F
P
S
F
L
S
R
Site 30
S368
T
L
H
T
Y
F
P
S
F
L
S
R
A
T
P
Site 31
S371
T
Y
F
P
S
F
L
S
R
A
T
P
S
C
P
Site 32
T374
P
S
F
L
S
R
A
T
P
S
C
P
P
E
M
Site 33
S376
F
L
S
R
A
T
P
S
C
P
P
E
M
K
K
Site 34
S401
T
V
D
P
L
S
A
S
V
W
R
Q
L
Y
P
Site 35
Y407
A
S
V
W
R
Q
L
Y
P
K
H
L
S
Q
S
Site 36
S412
Q
L
Y
P
K
H
L
S
Q
S
S
L
L
L
E
Site 37
S414
Y
P
K
H
L
S
Q
S
S
L
L
L
E
H
L
Site 38
S415
P
K
H
L
S
Q
S
S
L
L
L
E
H
L
L
Site 39
S423
L
L
L
E
H
L
L
S
S
W
E
Q
I
P
K
Site 40
S435
I
P
K
K
V
Q
K
S
L
Q
E
T
I
Q
S
Site 41
T439
V
Q
K
S
L
Q
E
T
I
Q
S
L
K
L
T
Site 42
S442
S
L
Q
E
T
I
Q
S
L
K
L
T
N
Q
E
Site 43
T446
T
I
Q
S
L
K
L
T
N
Q
E
L
L
R
K
Site 44
S455
Q
E
L
L
R
K
G
S
S
N
N
Q
D
V
V
Site 45
S503
F
L
C
H
D
L
R
S
H
S
S
F
Q
A
S
Site 46
S505
C
H
D
L
R
S
H
S
S
F
Q
A
S
L
T
Site 47
S506
H
D
L
R
S
H
S
S
F
Q
A
S
L
T
G
Site 48
S510
S
H
S
S
F
Q
A
S
L
T
G
R
L
L
R
Site 49
T512
S
S
F
Q
A
S
L
T
G
R
L
L
R
S
S
Site 50
S519
T
G
R
L
L
R
S
S
G
F
L
P
A
S
Q
Site 51
Y533
Q
Q
A
C
A
K
L
Y
S
Y
S
L
Q
G
Y
Site 52
S534
Q
A
C
A
K
L
Y
S
Y
S
L
Q
G
Y
S
Site 53
Y535
A
C
A
K
L
Y
S
Y
S
L
Q
G
Y
S
W
Site 54
Y540
Y
S
Y
S
L
Q
G
Y
S
W
L
G
E
T
L
Site 55
T546
G
Y
S
W
L
G
E
T
L
P
L
W
G
S
H
Site 56
S590
H
L
A
W
F
G
D
S
L
T
S
L
S
Q
R
Site 57
T592
A
W
F
G
D
S
L
T
S
L
S
Q
R
L
Q
Site 58
S593
W
F
G
D
S
L
T
S
L
S
Q
R
L
Q
I
Site 59
S595
G
D
S
L
T
S
L
S
Q
R
L
Q
I
Q
L
Site 60
S605
L
Q
I
Q
L
P
D
S
V
N
Q
L
L
R
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation