PhosphoNET

           
Protein Info 
   
Short Name:  HMBOX1
Full Name:  Homeobox-containing protein 1
Alias:  HMBX1; HNF1LA; Homeobox-containing 1; PBHNF
Type:  Transcription regulation
Mass (Da):  47278
Number AA:  420
UniProt ID:  Q6NT76
International Prot ID:  Isofrom1 - IPI00002265
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0043565  GO:0003700   PhosphoSite+ KinaseNET
Biological Process:  GO:0006355  GO:0006350   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S14VVLLETMSHYTDEPR
Site 2T23YTDEPRFTIEQIDLL
Site 3T36LLQRLRRTGMTKHEI
Site 4T39RLRRTGMTKHEILHA
Site 5T49EILHALETLDRLDQE
Site 6S58DRLDQEHSDKFGRRS
Site 7S65SDKFGRRSSYGGSSY
Site 8S66DKFGRRSSYGGSSYG
Site 9Y67KFGRRSSYGGSSYGN
Site 10S70RRSSYGGSSYGNSTN
Site 11S71RSSYGGSSYGNSTNN
Site 12S75GGSSYGNSTNNVPAS
Site 13S82STNNVPASSSTATAS
Site 14S84NNVPASSSTATASTQ
Site 15T87PASSSTATASTQTQH
Site 16S89SSSTATASTQTQHSG
Site 17S95ASTQTQHSGMSPSPS
Site 18S98QTQHSGMSPSPSNSY
Site 19S100QHSGMSPSPSNSYDT
Site 20S102SGMSPSPSNSYDTSP
Site 21S104MSPSPSNSYDTSPQP
Site 22S108PSNSYDTSPQPCTTN
Site 23S126RENNERLSTSNGKMS
Site 24T127ENNERLSTSNGKMSP
Site 25S128NNERLSTSNGKMSPT
Site 26S133STSNGKMSPTRYHAN
Site 27Y137GKMSPTRYHANSMGQ
Site 28S141PTRYHANSMGQRSYS
Site 29S146ANSMGQRSYSFEASE
Site 30Y147NSMGQRSYSFEASEE
Site 31S148SMGQRSYSFEASEED
Site 32S152RSYSFEASEEDLDVD
Site 33S170EELMRRDSSVIKEEI
Site 34S171ELMRRDSSVIKEEIK
Site 35S198VAQVTGISQSRISHW
Site 36S203GISQSRISHWLLQQG
Site 37S211HWLLQQGSDLSEQKK
Site 38S214LQQGSDLSEQKKRAF
Site 39Y222EQKKRAFYRWYQLEK
Site 40Y225KRAFYRWYQLEKTNP
Site 41T230RWYQLEKTNPGATLS
Site 42T235EKTNPGATLSMRPAP
Site 43S237TNPGATLSMRPAPIP
Site 44T253EDPEWRQTPPPVSAT
Site 45S258RQTPPPVSATSGTFR
Site 46T260TPPPVSATSGTFRLR
Site 47S261PPPVSATSGTFRLRR
Site 48T263PVSATSGTFRLRRGS
Site 49S270TFRLRRGSRFTWRKE
Site 50T273LRRGSRFTWRKECLA
Site 51Y285CLAVMESYFNENQYP
Site 52Y291SYFNENQYPDEAKRE
Site 53S316QKPGKKLSDLERVTS
Site 54T322LSDLERVTSLKVYNW
Site 55S323SDLERVTSLKVYNWF
Site 56Y327RVTSLKVYNWFANRR
Site 57S357SHGIDVQSPGGHSNS
Site 58S364SPGGHSNSDDVDGND
Site 59Y372DDVDGNDYSEQDDST
Site 60S373DVDGNDYSEQDDSTS
Site 61S378DYSEQDDSTSHSDHQ
Site 62T379YSEQDDSTSHSDHQD
Site 63S380SEQDDSTSHSDHQDP
Site 64S382QDDSTSHSDHQDPIS
Site 65S389SDHQDPISLAVEMAA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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