PhosphoNET

           
Protein Info 
   
Short Name:  CYP4F22
Full Name:  Cytochrome P450 4F22
Alias: 
Type: 
Mass (Da):  61958
Number AA:  531
UniProt ID:  Q6NT55
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y50LRLCRSFYITCRRLR
Site 2Y133APKDDLFYGFLKPWL
Site 3S147LGDGLLLSKGDKWSR
Site 4S153LSKGDKWSRHRRLLT
Site 5T160SRHRRLLTPAFHFDI
Site 6Y171HFDILKPYMKIFNQS
Site 7Y218LQKCVFSYNSNCQEK
Site 8Y245ALSVRRQYRLHHYLD
Site 9Y250RQYRLHHYLDFIYYR
Site 10Y255HHYLDFIYYRSADGR
Site 11Y256HYLDFIYYRSADGRR
Site 12S321DEDGKELSDEDIRAE
Site 13T331DIRAEADTFMFEGHD
Site 14S341FEGHDTTSSGISWML
Site 15S342EGHDTTSSGISWMLF
Site 16Y354MLFNLAKYPEYQEKC
Site 17Y357NLAKYPEYQEKCREE
Site 18T383ELEWDDLTQLPFTTM
Site 19Y399IKESLRQYPPVTLVS
Site 20T403LRQYPPVTLVSRQCT
Site 21T410TLVSRQCTEDIKLPD
Site 22S461PDNPQQRSPLAYVPF
Site 23Y465QQRSPLAYVPFSAGP
Site 24S469PLAYVPFSAGPRNCI
Site 25S479PRNCIGQSFAMAELR
Site 26S499TLLRFRLSVDRTRKV
Site 27T503FRLSVDRTRKVRRKP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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