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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF498
Full Name:
Zinc finger protein 498
Alias:
Zinc finger and SCAN domain-containing protein 25
Type:
Mass (Da):
61474
Number AA:
544
UniProt ID:
Q6NSZ9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S37
G
R
G
R
E
D
P
S
P
E
T
F
R
L
R
Site 2
T40
R
E
D
P
S
P
E
T
F
R
L
R
F
R
Q
Site 3
Y50
L
R
F
R
Q
F
R
Y
Q
E
A
A
G
P
Q
Site 4
T77
W
L
R
P
E
L
H
T
K
E
Q
I
L
E
L
Site 5
Y99
T
I
L
P
R
E
F
Y
A
W
I
R
E
H
G
Site 6
S109
I
R
E
H
G
P
E
S
G
K
A
L
A
A
M
Site 7
T121
A
A
M
V
E
D
L
T
E
R
A
L
E
A
K
Site 8
T141
R
Q
G
E
Q
E
E
T
A
L
C
R
G
A
W
Site 9
T178
V
Q
G
P
D
P
G
T
E
E
Q
L
S
Q
D
Site 10
S183
P
G
T
E
E
Q
L
S
Q
D
P
G
D
E
T
Site 11
T190
S
Q
D
P
G
D
E
T
R
A
F
Q
E
Q
A
Site 12
T248
E
E
E
W
R
H
V
T
P
A
Q
I
D
C
F
Site 13
Y258
Q
I
D
C
F
G
E
Y
V
E
P
Q
D
C
R
Site 14
S267
E
P
Q
D
C
R
V
S
P
G
G
G
S
K
E
Site 15
S300
S
E
R
F
G
E
A
S
L
Q
G
P
G
L
G
Site 16
S320
E
P
G
G
P
A
G
S
A
P
G
L
P
P
P
Site 17
T340
P
L
P
D
E
V
K
T
H
S
S
F
W
K
P
Site 18
S342
P
D
E
V
K
T
H
S
S
F
W
K
P
F
Q
Site 19
S358
P
E
C
G
K
G
F
S
R
S
S
N
L
V
R
Site 20
S360
C
G
K
G
F
S
R
S
S
N
L
V
R
H
Q
Site 21
S361
G
K
G
F
S
R
S
S
N
L
V
R
H
Q
R
Site 22
Y375
R
T
H
E
E
K
S
Y
G
C
V
E
C
G
K
Site 23
T385
V
E
C
G
K
G
F
T
L
R
E
Y
L
M
K
Site 24
Y389
K
G
F
T
L
R
E
Y
L
M
K
H
Q
R
T
Site 25
Y403
T
H
L
G
K
R
P
Y
V
C
S
E
C
W
K
Site 26
T426
E
V
H
Q
R
S
H
T
G
E
K
P
Y
K
C
Site 27
Y431
S
H
T
G
E
K
P
Y
K
C
G
D
C
W
K
Site 28
T452
H
L
Q
V
H
R
R
T
H
T
G
E
K
P
Y
Site 29
T454
Q
V
H
R
R
T
H
T
G
E
K
P
Y
T
C
Site 30
T460
H
T
G
E
K
P
Y
T
C
E
C
G
K
S
F
Site 31
S468
C
E
C
G
K
S
F
S
R
N
A
N
L
A
V
Site 32
T481
A
V
H
R
R
A
H
T
G
E
K
P
Y
G
C
Site 33
Y486
A
H
T
G
E
K
P
Y
G
C
Q
V
C
G
K
Site 34
S496
Q
V
C
G
K
R
F
S
K
G
E
R
L
V
R
Site 35
T509
V
R
H
Q
R
I
H
T
G
E
K
P
Y
H
C
Site 36
Y514
I
H
T
G
E
K
P
Y
H
C
P
A
C
G
R
Site 37
S527
G
R
S
F
N
Q
R
S
I
L
N
R
H
Q
K
Site 38
T535
I
L
N
R
H
Q
K
T
Q
H
R
Q
E
P
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation