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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF280D
Full Name:
Zinc finger protein 280D
Alias:
FLJ20086; SUHW4; Suppressor of hairy wing 4; Suppressor of hairy wing homologue 4; Z280D; ZNF634
Type:
Mass (Da):
109285
Number AA:
979
UniProt ID:
Q6N043
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
D
N
P
F
Q
P
K
S
N
S
K
M
A
E
L
Site 2
S12
P
F
Q
P
K
S
N
S
K
M
A
E
L
F
M
Site 3
S58
S
S
S
K
P
A
I
S
N
I
L
N
R
V
N
Site 4
S68
L
N
R
V
N
P
S
S
Y
S
R
G
L
K
N
Site 5
S90
T
A
A
F
K
P
T
S
Q
H
Y
T
N
P
T
Site 6
Y93
F
K
P
T
S
Q
H
Y
T
N
P
T
S
N
P
Site 7
T94
K
P
T
S
Q
H
Y
T
N
P
T
S
N
P
V
Site 8
T97
S
Q
H
Y
T
N
P
T
S
N
P
V
P
A
S
Site 9
S98
Q
H
Y
T
N
P
T
S
N
P
V
P
A
S
P
Site 10
S104
T
S
N
P
V
P
A
S
P
I
N
F
H
P
E
Site 11
S112
P
I
N
F
H
P
E
S
R
S
S
D
S
S
V
Site 12
S114
N
F
H
P
E
S
R
S
S
D
S
S
V
I
V
Site 13
S115
F
H
P
E
S
R
S
S
D
S
S
V
I
V
Q
Site 14
S117
P
E
S
R
S
S
D
S
S
V
I
V
Q
P
F
Site 15
S118
E
S
R
S
S
D
S
S
V
I
V
Q
P
F
S
Site 16
S125
S
V
I
V
Q
P
F
S
K
P
G
Y
I
T
N
Site 17
Y129
Q
P
F
S
K
P
G
Y
I
T
N
S
S
R
V
Site 18
S133
K
P
G
Y
I
T
N
S
S
R
V
V
S
N
K
Site 19
S134
P
G
Y
I
T
N
S
S
R
V
V
S
N
K
S
Site 20
S138
T
N
S
S
R
V
V
S
N
K
S
S
E
L
L
Site 21
S141
S
R
V
V
S
N
K
S
S
E
L
L
F
D
L
Site 22
S142
R
V
V
S
N
K
S
S
E
L
L
F
D
L
T
Site 23
T149
S
E
L
L
F
D
L
T
Q
D
T
G
L
S
H
Site 24
S155
L
T
Q
D
T
G
L
S
H
Y
Q
G
G
P
T
Site 25
T162
S
H
Y
Q
G
G
P
T
L
S
M
A
G
M
S
Site 26
S164
Y
Q
G
G
P
T
L
S
M
A
G
M
S
E
S
Site 27
S169
T
L
S
M
A
G
M
S
E
S
S
F
L
S
K
Site 28
S172
M
A
G
M
S
E
S
S
F
L
S
K
R
P
S
Site 29
S175
M
S
E
S
S
F
L
S
K
R
P
S
T
S
E
Site 30
S179
S
F
L
S
K
R
P
S
T
S
E
V
N
N
V
Site 31
T180
F
L
S
K
R
P
S
T
S
E
V
N
N
V
N
Site 32
S181
L
S
K
R
P
S
T
S
E
V
N
N
V
N
P
Site 33
S194
N
P
K
K
P
K
P
S
E
S
V
S
G
A
N
Site 34
S196
K
K
P
K
P
S
E
S
V
S
G
A
N
S
S
Site 35
S198
P
K
P
S
E
S
V
S
G
A
N
S
S
A
V
Site 36
S203
S
V
S
G
A
N
S
S
A
V
L
P
S
V
K
Site 37
S208
N
S
S
A
V
L
P
S
V
K
S
P
S
V
T
Site 38
S211
A
V
L
P
S
V
K
S
P
S
V
T
S
S
Q
Site 39
S213
L
P
S
V
K
S
P
S
V
T
S
S
Q
A
M
Site 40
T215
S
V
K
S
P
S
V
T
S
S
Q
A
M
L
A
Site 41
S217
K
S
P
S
V
T
S
S
Q
A
M
L
A
K
G
Site 42
S229
A
K
G
T
N
T
S
S
N
Q
S
K
N
G
T
Site 43
S232
T
N
T
S
S
N
Q
S
K
N
G
T
P
F
P
Site 44
T236
S
N
Q
S
K
N
G
T
P
F
P
R
A
C
P
Site 45
T276
N
F
L
G
L
A
K
T
E
F
S
S
T
V
N
Site 46
T281
A
K
T
E
F
S
S
T
V
N
K
N
T
T
I
Site 47
T286
S
S
T
V
N
K
N
T
T
I
D
S
E
K
G
Site 48
S290
N
K
N
T
T
I
D
S
E
K
G
K
L
I
M
Site 49
Y303
I
M
L
V
N
D
F
Y
Y
G
K
H
E
G
D
Site 50
Y304
M
L
V
N
D
F
Y
Y
G
K
H
E
G
D
V
Site 51
T317
D
V
Q
E
E
Q
K
T
H
T
T
F
K
C
F
Site 52
S351
L
E
L
E
K
Q
S
S
E
S
W
E
N
H
T
Site 53
T380
L
Q
C
H
I
E
S
T
H
T
P
H
E
F
S
Site 54
T382
C
H
I
E
S
T
H
T
P
H
E
F
S
T
I
Site 55
Y418
H
K
P
G
E
M
P
Y
V
C
Q
V
C
N
Y
Site 56
Y425
Y
V
C
Q
V
C
N
Y
R
S
S
S
F
S
D
Site 57
S427
C
Q
V
C
N
Y
R
S
S
S
F
S
D
V
E
Site 58
S428
Q
V
C
N
Y
R
S
S
S
F
S
D
V
E
T
Site 59
S429
V
C
N
Y
R
S
S
S
F
S
D
V
E
T
H
Site 60
S431
N
Y
R
S
S
S
F
S
D
V
E
T
H
F
R
Site 61
T435
S
S
F
S
D
V
E
T
H
F
R
T
S
H
E
Site 62
S440
V
E
T
H
F
R
T
S
H
E
N
T
K
N
L
Site 63
Y462
V
I
K
I
A
T
P
Y
M
H
H
Y
M
K
H
Site 64
T500
H
K
T
Q
H
H
R
T
F
I
K
P
K
Q
L
Site 65
T517
L
P
P
G
T
K
V
T
I
R
A
S
V
G
P
Site 66
S521
T
K
V
T
I
R
A
S
V
G
P
L
Q
S
G
Site 67
S527
A
S
V
G
P
L
Q
S
G
A
S
P
T
P
S
Site 68
S530
G
P
L
Q
S
G
A
S
P
T
P
S
I
S
A
Site 69
T532
L
Q
S
G
A
S
P
T
P
S
I
S
A
S
A
Site 70
S534
S
G
A
S
P
T
P
S
I
S
A
S
A
S
T
Site 71
S536
A
S
P
T
P
S
I
S
A
S
A
S
T
L
Q
Site 72
S538
P
T
P
S
I
S
A
S
A
S
T
L
Q
L
S
Site 73
S540
P
S
I
S
A
S
A
S
T
L
Q
L
S
P
P
Site 74
T541
S
I
S
A
S
A
S
T
L
Q
L
S
P
P
R
Site 75
S545
S
A
S
T
L
Q
L
S
P
P
R
T
K
N
I
Site 76
T549
L
Q
L
S
P
P
R
T
K
N
I
T
A
K
N
Site 77
T553
P
P
R
T
K
N
I
T
A
K
N
P
A
K
S
Site 78
S560
T
A
K
N
P
A
K
S
N
T
S
K
P
N
T
Site 79
T567
S
N
T
S
K
P
N
T
V
K
S
N
A
S
K
Site 80
S570
S
K
P
N
T
V
K
S
N
A
S
K
P
N
T
Site 81
T577
S
N
A
S
K
P
N
T
S
K
P
N
G
S
K
Site 82
S578
N
A
S
K
P
N
T
S
K
P
N
G
S
K
S
Site 83
S583
N
T
S
K
P
N
G
S
K
S
K
Y
K
P
K
Site 84
S585
S
K
P
N
G
S
K
S
K
Y
K
P
K
I
S
Site 85
Y587
P
N
G
S
K
S
K
Y
K
P
K
I
S
N
M
Site 86
S592
S
K
Y
K
P
K
I
S
N
M
Q
K
K
Q
S
Site 87
S599
S
N
M
Q
K
K
Q
S
T
L
A
S
S
N
K
Site 88
T600
N
M
Q
K
K
Q
S
T
L
A
S
S
N
K
K
Site 89
S603
K
K
Q
S
T
L
A
S
S
N
K
K
S
K
V
Site 90
S604
K
Q
S
T
L
A
S
S
N
K
K
S
K
V
N
Site 91
S608
L
A
S
S
N
K
K
S
K
V
N
T
A
L
R
Site 92
T612
N
K
K
S
K
V
N
T
A
L
R
N
L
R
Y
Site 93
Y619
T
A
L
R
N
L
R
Y
R
R
G
I
H
K
C
Site 94
T653
C
S
F
C
R
Y
N
T
S
C
S
K
A
Y
V
Site 95
S737
I
P
T
S
E
H
L
S
E
L
K
K
E
A
P
Site 96
S752
A
K
E
Q
E
P
V
S
K
E
I
A
R
P
N
Site 97
T765
P
N
M
A
E
R
E
T
E
T
S
N
S
E
S
Site 98
S768
A
E
R
E
T
E
T
S
N
S
E
S
K
Q
D
Site 99
S770
R
E
T
E
T
S
N
S
E
S
K
Q
D
K
A
Site 100
S772
T
E
T
S
N
S
E
S
K
Q
D
K
A
A
S
Site 101
S790
K
N
G
C
N
A
N
S
F
E
G
S
S
T
T
Site 102
S794
N
A
N
S
F
E
G
S
S
T
T
K
S
E
E
Site 103
S795
A
N
S
F
E
G
S
S
T
T
K
S
E
E
S
Site 104
T796
N
S
F
E
G
S
S
T
T
K
S
E
E
S
I
Site 105
S799
E
G
S
S
T
T
K
S
E
E
S
I
T
V
S
Site 106
S802
S
T
T
K
S
E
E
S
I
T
V
S
D
K
E
Site 107
T804
T
K
S
E
E
S
I
T
V
S
D
K
E
N
E
Site 108
S806
S
E
E
S
I
T
V
S
D
K
E
N
E
T
C
Site 109
T819
T
C
L
A
D
Q
E
T
G
S
K
N
I
V
S
Site 110
S821
L
A
D
Q
E
T
G
S
K
N
I
V
S
C
D
Site 111
S826
T
G
S
K
N
I
V
S
C
D
S
N
I
G
A
Site 112
S856
M
E
L
K
M
C
Q
S
S
E
N
I
I
L
S
Site 113
S857
E
L
K
M
C
Q
S
S
E
N
I
I
L
S
D
Site 114
S863
S
S
E
N
I
I
L
S
D
Q
I
K
D
H
N
Site 115
S871
D
Q
I
K
D
H
N
S
S
E
A
R
F
S
S
Site 116
S872
Q
I
K
D
H
N
S
S
E
A
R
F
S
S
K
Site 117
S877
N
S
S
E
A
R
F
S
S
K
N
I
K
D
L
Site 118
S878
S
S
E
A
R
F
S
S
K
N
I
K
D
L
R
Site 119
S888
I
K
D
L
R
L
A
S
D
N
V
S
I
D
Q
Site 120
S892
R
L
A
S
D
N
V
S
I
D
Q
F
L
R
K
Site 121
S905
R
K
R
H
E
P
E
S
V
S
S
D
V
S
E
Site 122
S907
R
H
E
P
E
S
V
S
S
D
V
S
E
Q
G
Site 123
S908
H
E
P
E
S
V
S
S
D
V
S
E
Q
G
S
Site 124
S911
E
S
V
S
S
D
V
S
E
Q
G
S
I
H
L
Site 125
S915
S
D
V
S
E
Q
G
S
I
H
L
E
P
L
T
Site 126
T922
S
I
H
L
E
P
L
T
P
S
E
V
L
E
Y
Site 127
Y929
T
P
S
E
V
L
E
Y
E
A
T
E
I
L
Q
Site 128
T932
E
V
L
E
Y
E
A
T
E
I
L
Q
K
G
S
Site 129
S939
T
E
I
L
Q
K
G
S
G
D
P
S
A
K
T
Site 130
S943
Q
K
G
S
G
D
P
S
A
K
T
D
E
V
V
Site 131
T946
S
G
D
P
S
A
K
T
D
E
V
V
S
D
Q
Site 132
T954
D
E
V
V
S
D
Q
T
D
D
I
P
G
G
N
Site 133
T965
P
G
G
N
N
P
S
T
T
E
A
T
V
D
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation