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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KRT80
Full Name:
Keratin, type II cytoskeletal 80
Alias:
K2C80; KB20; Keratin 80; Keratin b20; Type II keratin
Type:
Mass (Da):
50525
Number AA:
452
UniProt ID:
Q6KB66
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0045095
GO:0044422
GO:0044424
Uniprot
OncoNet
Molecular Function:
GO:0005198
GO:0005198
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T19
S
L
S
S
C
E
V
T
P
V
G
S
P
R
P
Site 2
S23
C
E
V
T
P
V
G
S
P
R
P
G
T
S
G
Site 3
T28
V
G
S
P
R
P
G
T
S
G
W
D
S
C
R
Site 4
S29
G
S
P
R
P
G
T
S
G
W
D
S
C
R
A
Site 5
S33
P
G
T
S
G
W
D
S
C
R
A
P
G
P
G
Site 6
S42
R
A
P
G
P
G
F
S
S
R
S
L
T
G
C
Site 7
S43
A
P
G
P
G
F
S
S
R
S
L
T
G
C
W
Site 8
S45
G
P
G
F
S
S
R
S
L
T
G
C
W
S
A
Site 9
T47
G
F
S
S
R
S
L
T
G
C
W
S
A
G
T
Site 10
S51
R
S
L
T
G
C
W
S
A
G
T
I
S
K
V
Site 11
S116
Q
L
L
E
T
R
W
S
F
L
Q
G
Q
D
S
Site 12
S123
S
F
L
Q
G
Q
D
S
A
I
F
D
L
G
H
Site 13
Y132
I
F
D
L
G
H
L
Y
E
E
Y
Q
G
R
L
Site 14
Y135
L
G
H
L
Y
E
E
Y
Q
G
R
L
Q
E
E
Site 15
S147
Q
E
E
L
R
K
V
S
Q
E
R
G
Q
L
E
Site 16
Y171
V
E
E
F
R
I
R
Y
E
D
E
I
S
K
R
Site 17
S176
I
R
Y
E
D
E
I
S
K
R
T
D
M
E
F
Site 18
T184
K
R
T
D
M
E
F
T
F
V
Q
L
K
K
D
Site 19
T204
L
H
R
T
E
L
E
T
K
L
K
S
L
E
S
Site 20
S208
E
L
E
T
K
L
K
S
L
E
S
F
V
E
L
Site 21
S211
T
K
L
K
S
L
E
S
F
V
E
L
M
K
T
Site 22
T218
S
F
V
E
L
M
K
T
I
Y
E
Q
E
L
K
Site 23
Y220
V
E
L
M
K
T
I
Y
E
Q
E
L
K
D
L
Site 24
S242
S
V
T
V
G
M
D
S
R
C
H
I
D
L
S
Site 25
S249
S
R
C
H
I
D
L
S
G
I
V
E
E
V
K
Site 26
S266
Y
D
A
V
A
A
R
S
L
E
E
A
E
A
Y
Site 27
Y273
S
L
E
E
A
E
A
Y
S
R
S
Q
L
E
E
Site 28
S290
A
R
S
A
E
Y
G
S
S
L
Q
S
S
R
S
Site 29
S291
R
S
A
E
Y
G
S
S
L
Q
S
S
R
S
E
Site 30
S294
E
Y
G
S
S
L
Q
S
S
R
S
E
I
A
D
Site 31
S295
Y
G
S
S
L
Q
S
S
R
S
E
I
A
D
L
Site 32
S297
S
S
L
Q
S
S
R
S
E
I
A
D
L
N
V
Site 33
S311
V
R
I
Q
K
L
R
S
Q
I
L
S
V
K
S
Site 34
S315
K
L
R
S
Q
I
L
S
V
K
S
H
C
L
K
Site 35
S318
S
Q
I
L
S
V
K
S
H
C
L
K
L
E
E
Site 36
T329
K
L
E
E
N
I
K
T
A
E
E
Q
G
E
L
Site 37
T343
L
A
F
Q
D
A
K
T
K
L
A
Q
L
E
A
Site 38
Y366
M
A
R
Q
L
R
K
Y
Q
E
L
M
N
V
K
Site 39
Y383
L
D
I
E
I
A
T
Y
R
K
L
V
E
G
E
Site 40
S396
G
E
E
G
R
M
D
S
P
S
A
T
V
V
S
Site 41
S398
E
G
R
M
D
S
P
S
A
T
V
V
S
A
V
Site 42
T400
R
M
D
S
P
S
A
T
V
V
S
A
V
Q
S
Site 43
S403
S
P
S
A
T
V
V
S
A
V
Q
S
R
C
K
Site 44
T411
A
V
Q
S
R
C
K
T
A
A
S
R
S
G
L
Site 45
S414
S
R
C
K
T
A
A
S
R
S
G
L
S
K
A
Site 46
S419
A
A
S
R
S
G
L
S
K
A
P
S
R
K
K
Site 47
S423
S
G
L
S
K
A
P
S
R
K
K
K
G
S
K
Site 48
S429
P
S
R
K
K
K
G
S
K
G
P
V
I
K
I
Site 49
T437
K
G
P
V
I
K
I
T
E
M
S
E
K
Y
F
Site 50
S440
V
I
K
I
T
E
M
S
E
K
Y
F
S
Q
E
Site 51
Y443
I
T
E
M
S
E
K
Y
F
S
Q
E
S
E
V
Site 52
S445
E
M
S
E
K
Y
F
S
Q
E
S
E
V
S
E
Site 53
S448
E
K
Y
F
S
Q
E
S
E
V
S
E
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation