PhosphoNET

           
Protein Info 
   
Short Name:  RAB12
Full Name:  Ras-related protein Rab-12
Alias:  FLJ45927; RAB12, member RAS oncogene family
Type: 
Mass (Da):  27248
Number AA:  244
UniProt ID:  Q6IQ22
International Prot ID:  IPI00419932
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005794  GO:0031225   Uniprot OncoNet
Molecular Function:  GO:0005525     PhosphoSite+ KinaseNET
Biological Process:  GO:0015031  GO:0007264   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S21GGGLGAGSPALSGGQ
Site 2S25GAGSPALSGGQGRRR
Site 3T56GSRGVGKTSLMERFT
Site 4S57SRGVGKTSLMERFTD
Site 5T63TSLMERFTDDTFCEA
Site 6T83GVDFKIKTVELRGKK
Site 7T98IRLQIWDTAGQERFN
Site 8S106AGQERFNSITSAYYR
Site 9T108QERFNSITSAYYRSA
Site 10S109ERFNSITSAYYRSAK
Site 11Y111FNSITSAYYRSAKGI
Site 12Y112NSITSAYYRSAKGII
Site 13T125IILVYDITKKETFDD
Site 14T129YDITKKETFDDLPKW
Site 15Y143WMKMIDKYASEDAEL
Site 16T161GNKLDCETDREITRQ
Site 17T166CETDREITRQQGEKF
Site 18S218DILRNELSNSILSLQ
Site 19S220LRNELSNSILSLQPE
Site 20S223ELSNSILSLQPEPEI
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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