PhosphoNET

           
Protein Info 
   
Short Name:  ASTL
Full Name:  Astacin-like metalloendopeptidase
Alias:  Oocyte astacin;Ovastacin
Type: 
Mass (Da):  45964
Number AA:  431
UniProt ID:  Q6HA08
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T43TSFPDGLTPEGTQAS
Site 2T47DGLTPEGTQASGDKD
Site 3S70ILEETPESSFLIEGD
Site 4S71LEETPESSFLIEGDI
Site 5S82EGDIIRPSPFRLLSA
Site 6S88PSPFRLLSATSNKWP
Site 7T90PFRLLSATSNKWPMG
Site 8S91FRLLSATSNKWPMGG
Site 9S99NKWPMGGSGVVEVPF
Site 10S110EVPFLLSSKYDEPSR
Site 11Y112PFLLSSKYDEPSRQV
Site 12S116SSKYDEPSRQVILEA
Site 13S156PMYGCFSSVGRSGGM
Site 14T171QVVSLAPTCLQKGRG
Site 15Y202TRADRDRYIRVNWNE
Site 16S221FEINFIKSRSSNMLT
Site 17S223INFIKSRSSNMLTPY
Site 18S224NFIKSRSSNMLTPYD
Site 19T228SRSSNMLTPYDYSSV
Site 20Y230SSNMLTPYDYSSVMH
Site 21Y232NMLTPYDYSSVMHYG
Site 22Y238DYSSVMHYGRLAFSR
Site 23S244HYGRLAFSRRGLPTI
Site 24T250FSRRGLPTITPLWAP
Site 25T252RRGLPTITPLWAPSV
Site 26S268IGQRWNLSASDITRV
Site 27S282VLKLYGCSPSGPRPR
Site 28S284KLYGCSPSGPRPRGR
Site 29S293PRPRGRGSHAHSTGR
Site 30S297GRGSHAHSTGRSPAP
Site 31T298RGSHAHSTGRSPAPA
Site 32S301HAHSTGRSPAPASLS
Site 33S306GRSPAPASLSLQRLL
Site 34S317QRLLEALSAESRSPD
Site 35S320LEALSAESRSPDPSG
Site 36S322ALSAESRSPDPSGSS
Site 37S326ESRSPDPSGSSAGGQ
Site 38S328RSPDPSGSSAGGQPV
Site 39S329SPDPSGSSAGGQPVP
Site 40S342VPAGPGESPHGWESP
Site 41S348ESPHGWESPALKKLS
Site 42S355SPALKKLSAEASARQ
Site 43S359KKLSAEASARQPQTL
Site 44T365ASARQPQTLASSPRS
Site 45S368RQPQTLASSPRSRPG
Site 46S369QPQTLASSPRSRPGA
Site 47S372TLASSPRSRPGAGAP
Site 48S386PGVAQEQSWLAGVST
Site 49S392QSWLAGVSTKPTVPS
Site 50T393SWLAGVSTKPTVPSS
Site 51T396AGVSTKPTVPSSEAG
Site 52S400TKPTVPSSEAGIQPV
Site 53S412QPVPVQGSPALPGGC
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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