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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
abLIM2
Full Name:
Actin-binding LIM protein 2
Alias:
abLIM-2; ABLM2; Actin-binding LIM 2; KIAA1808
Type:
Cytoskeletal protein; Myofibril, actin cytoskeleton protein
Mass (Da):
67812
Number AA:
611
UniProt ID:
Q6H8Q1
International Prot ID:
IPI00434484
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0015629
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0007010
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
S
Q
P
Q
A
A
P
S
P
L
E
K
S
P
S
Site 2
S17
A
P
S
P
L
E
K
S
P
S
T
A
I
L
C
Site 3
S19
S
P
L
E
K
S
P
S
T
A
I
L
C
N
T
Site 4
T72
R
Q
G
E
Y
I
C
T
L
D
Y
Q
R
L
Y
Site 5
Y75
E
Y
I
C
T
L
D
Y
Q
R
L
Y
G
T
R
Site 6
Y79
T
L
D
Y
Q
R
L
Y
G
T
R
C
F
S
C
Site 7
T123
F
P
P
G
D
R
V
T
F
N
G
K
E
C
M
Site 8
S147
V
G
S
S
A
H
L
S
Q
G
L
R
S
C
G
Site 9
S152
H
L
S
Q
G
L
R
S
C
G
G
C
G
T
E
Site 10
Y191
G
K
L
L
N
A
E
Y
I
S
K
D
G
L
P
Site 11
Y204
L
P
Y
C
E
A
D
Y
H
A
K
F
G
I
R
Site 12
Y218
R
C
D
S
C
E
K
Y
I
T
G
R
V
L
E
Site 13
T220
D
S
C
E
K
Y
I
T
G
R
V
L
E
A
G
Site 14
Y252
F
A
E
G
E
E
M
Y
L
Q
G
S
S
I
W
Site 15
T269
A
C
R
Q
A
A
R
T
E
D
R
N
K
E
T
Site 16
T276
T
E
D
R
N
K
E
T
R
T
S
S
E
S
I
Site 17
T278
D
R
N
K
E
T
R
T
S
S
E
S
I
I
S
Site 18
S279
R
N
K
E
T
R
T
S
S
E
S
I
I
S
V
Site 19
S280
N
K
E
T
R
T
S
S
E
S
I
I
S
V
P
Site 20
S282
E
T
R
T
S
S
E
S
I
I
S
V
P
A
S
Site 21
S285
T
S
S
E
S
I
I
S
V
P
A
S
S
T
S
Site 22
S289
S
I
I
S
V
P
A
S
S
T
S
G
S
P
S
Site 23
S290
I
I
S
V
P
A
S
S
T
S
G
S
P
S
R
Site 24
T291
I
S
V
P
A
S
S
T
S
G
S
P
S
R
V
Site 25
S292
S
V
P
A
S
S
T
S
G
S
P
S
R
V
I
Site 26
S294
P
A
S
S
T
S
G
S
P
S
R
V
I
Y
A
Site 27
S296
S
S
T
S
G
S
P
S
R
V
I
Y
A
K
L
Site 28
Y300
G
S
P
S
R
V
I
Y
A
K
L
G
G
E
I
Site 29
S319
D
L
A
A
L
P
K
S
K
A
I
Y
D
I
D
Site 30
Y323
L
P
K
S
K
A
I
Y
D
I
D
R
P
D
M
Site 31
S332
I
D
R
P
D
M
I
S
Y
S
P
Y
I
S
H
Site 32
Y333
D
R
P
D
M
I
S
Y
S
P
Y
I
S
H
S
Site 33
S334
R
P
D
M
I
S
Y
S
P
Y
I
S
H
S
A
Site 34
Y336
D
M
I
S
Y
S
P
Y
I
S
H
S
A
G
D
Site 35
S338
I
S
Y
S
P
Y
I
S
H
S
A
G
D
R
Q
Site 36
S340
Y
S
P
Y
I
S
H
S
A
G
D
R
Q
S
Y
Site 37
S346
H
S
A
G
D
R
Q
S
Y
G
E
G
D
Q
D
Site 38
Y347
S
A
G
D
R
Q
S
Y
G
E
G
D
Q
D
D
Site 39
S356
E
G
D
Q
D
D
R
S
Y
K
Q
C
R
T
S
Site 40
Y357
G
D
Q
D
D
R
S
Y
K
Q
C
R
T
S
S
Site 41
T362
R
S
Y
K
Q
C
R
T
S
S
P
S
S
T
G
Site 42
S363
S
Y
K
Q
C
R
T
S
S
P
S
S
T
G
S
Site 43
S364
Y
K
Q
C
R
T
S
S
P
S
S
T
G
S
V
Site 44
S366
Q
C
R
T
S
S
P
S
S
T
G
S
V
S
L
Site 45
S367
C
R
T
S
S
P
S
S
T
G
S
V
S
L
G
Site 46
T368
R
T
S
S
P
S
S
T
G
S
V
S
L
G
R
Site 47
S370
S
S
P
S
S
T
G
S
V
S
L
G
R
Y
T
Site 48
S372
P
S
S
T
G
S
V
S
L
G
R
Y
T
P
T
Site 49
Y376
G
S
V
S
L
G
R
Y
T
P
T
S
R
S
P
Site 50
T377
S
V
S
L
G
R
Y
T
P
T
S
R
S
P
Q
Site 51
T379
S
L
G
R
Y
T
P
T
S
R
S
P
Q
H
Y
Site 52
S380
L
G
R
Y
T
P
T
S
R
S
P
Q
H
Y
S
Site 53
S382
R
Y
T
P
T
S
R
S
P
Q
H
Y
S
R
P
Site 54
Y386
T
S
R
S
P
Q
H
Y
S
R
P
G
S
E
S
Site 55
S387
S
R
S
P
Q
H
Y
S
R
P
G
S
E
S
G
Site 56
S391
Q
H
Y
S
R
P
G
S
E
S
G
R
S
T
P
Site 57
S393
Y
S
R
P
G
S
E
S
G
R
S
T
P
S
L
Site 58
S396
P
G
S
E
S
G
R
S
T
P
S
L
S
V
L
Site 59
T397
G
S
E
S
G
R
S
T
P
S
L
S
V
L
S
Site 60
S399
E
S
G
R
S
T
P
S
L
S
V
L
S
D
S
Site 61
S401
G
R
S
T
P
S
L
S
V
L
S
D
S
K
P
Site 62
S404
T
P
S
L
S
V
L
S
D
S
K
P
P
P
S
Site 63
S406
S
L
S
V
L
S
D
S
K
P
P
P
S
T
Y
Site 64
S411
S
D
S
K
P
P
P
S
T
Y
Q
Q
A
P
R
Site 65
T412
D
S
K
P
P
P
S
T
Y
Q
Q
A
P
R
H
Site 66
Y413
S
K
P
P
P
S
T
Y
Q
Q
A
P
R
H
F
Site 67
T425
R
H
F
H
V
P
D
T
G
V
K
D
N
I
Y
Site 68
Y432
T
G
V
K
D
N
I
Y
R
K
P
P
I
Y
R
Site 69
Y438
I
Y
R
K
P
P
I
Y
R
Q
H
A
A
R
R
Site 70
S446
R
Q
H
A
A
R
R
S
D
G
E
D
G
S
L
Site 71
S452
R
S
D
G
E
D
G
S
L
D
Q
D
N
R
K
Site 72
S461
D
Q
D
N
R
K
K
S
S
W
L
M
L
K
G
Site 73
S462
Q
D
N
R
K
K
S
S
W
L
M
L
K
G
D
Site 74
T472
M
L
K
G
D
A
D
T
R
T
N
S
P
D
L
Site 75
T474
K
G
D
A
D
T
R
T
N
S
P
D
L
D
T
Site 76
S476
D
A
D
T
R
T
N
S
P
D
L
D
T
Q
S
Site 77
T481
T
N
S
P
D
L
D
T
Q
S
L
S
H
S
S
Site 78
S483
S
P
D
L
D
T
Q
S
L
S
H
S
S
G
T
Site 79
S485
D
L
D
T
Q
S
L
S
H
S
S
G
T
D
R
Site 80
S487
D
T
Q
S
L
S
H
S
S
G
T
D
R
D
P
Site 81
T490
S
L
S
H
S
S
G
T
D
R
D
P
L
Q
R
Site 82
S502
L
Q
R
M
A
G
D
S
F
H
S
R
F
P
Y
Site 83
Y509
S
F
H
S
R
F
P
Y
S
K
S
D
P
L
P
Site 84
S510
F
H
S
R
F
P
Y
S
K
S
D
P
L
P
G
Site 85
S512
S
R
F
P
Y
S
K
S
D
P
L
P
G
H
G
Site 86
Y546
A
S
W
G
M
R
E
Y
K
I
Y
P
Y
D
S
Site 87
Y549
G
M
R
E
Y
K
I
Y
P
Y
D
S
L
I
V
Site 88
Y551
R
E
Y
K
I
Y
P
Y
D
S
L
I
V
T
N
Site 89
T557
P
Y
D
S
L
I
V
T
N
R
I
R
V
K
L
Site 90
S578
T
R
L
E
R
H
L
S
P
E
E
F
Q
E
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation