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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RLTPR
Full Name:
Leucine-rich repeat-containing protein 16C
Alias:
Leucine rich repeat containing 16C; LRRC16C; RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing; RGD, leucine-rich repeat, tropomodulin and proline-rich containing; RGD, leucine-rich repeat, tropomodulin and proline-rich containing protein
Type:
Mass (Da):
158560
Number AA:
UniProt ID:
Q6F5E8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
Q
T
P
D
G
I
S
C
E
L
R
G
E
I
Site 2
T80
Q
A
M
A
L
Q
E
T
P
P
Q
V
T
F
E
Site 3
T85
Q
E
T
P
P
Q
V
T
F
E
L
E
S
L
R
Site 4
S122
I
K
K
V
F
P
R
S
T
L
G
K
L
F
R
Site 5
T123
K
K
V
F
P
R
S
T
L
G
K
L
F
R
R
Site 6
T132
G
K
L
F
R
R
P
T
P
A
S
M
L
A
R
Site 7
S135
F
R
R
P
T
P
A
S
M
L
A
R
L
E
R
Site 8
S143
M
L
A
R
L
E
R
S
S
P
S
E
S
T
D
Site 9
S144
L
A
R
L
E
R
S
S
P
S
E
S
T
D
P
Site 10
S146
R
L
E
R
S
S
P
S
E
S
T
D
P
C
S
Site 11
S148
E
R
S
S
P
S
E
S
T
D
P
C
S
P
C
Site 12
T149
R
S
S
P
S
E
S
T
D
P
C
S
P
C
G
Site 13
S153
S
E
S
T
D
P
C
S
P
C
G
G
F
L
E
Site 14
Y162
C
G
G
F
L
E
T
Y
E
A
L
C
D
Y
N
Site 15
Y168
T
Y
E
A
L
C
D
Y
N
G
F
P
F
R
E
Site 16
S194
R
Q
G
C
R
H
F
S
L
G
D
F
S
H
L
Site 17
S199
H
F
S
L
G
D
F
S
H
L
G
S
R
D
L
Site 18
S203
G
D
F
S
H
L
G
S
R
D
L
A
L
S
V
Site 19
S242
E
Q
I
L
H
M
M
S
Q
S
S
H
L
E
E
Site 20
S274
Q
A
L
A
G
H
S
S
S
G
L
R
E
L
S
Site 21
S275
A
L
A
G
H
S
S
S
G
L
R
E
L
S
L
Site 22
S281
S
S
G
L
R
E
L
S
L
A
G
N
L
L
D
Site 23
T293
L
L
D
D
R
G
M
T
A
L
S
R
H
L
E
Site 24
T314
R
R
L
S
L
A
Q
T
G
L
T
P
R
G
M
Site 25
T317
S
L
A
Q
T
G
L
T
P
R
G
M
R
A
L
Site 26
T337
T
N
A
A
F
D
S
T
L
T
H
L
D
L
S
Site 27
S353
N
P
G
A
L
G
A
S
E
D
S
G
G
L
Y
Site 28
Y360
S
E
D
S
G
G
L
Y
S
F
L
S
R
P
N
Site 29
S361
E
D
S
G
G
L
Y
S
F
L
S
R
P
N
V
Site 30
T383
G
T
D
T
A
L
D
T
V
R
G
C
S
V
G
Site 31
T433
R
G
C
C
T
S
L
T
H
L
D
A
S
R
N
Site 32
S438
S
L
T
H
L
D
A
S
R
N
V
F
S
R
T
Site 33
S443
D
A
S
R
N
V
F
S
R
T
K
S
R
A
A
Site 34
S447
N
V
F
S
R
T
K
S
R
A
A
P
A
A
L
Site 35
S500
R
D
L
H
L
D
L
S
A
C
E
L
R
S
A
Site 36
T565
F
N
V
R
C
K
E
T
L
D
D
V
L
H
R
Site 37
S586
D
D
D
C
P
L
Q
S
L
S
V
A
E
S
R
Site 38
S588
D
C
P
L
Q
S
L
S
V
A
E
S
R
L
K
Site 39
S592
Q
S
L
S
V
A
E
S
R
L
K
L
G
A
S
Site 40
S637
A
K
A
L
R
V
N
S
R
L
R
S
V
V
W
Site 41
S641
R
V
N
S
R
L
R
S
V
V
W
D
R
N
H
Site 42
T649
V
V
W
D
R
N
H
T
S
A
L
G
L
L
D
Site 43
S650
V
W
D
R
N
H
T
S
A
L
G
L
L
D
V
Site 44
S666
Q
A
L
E
Q
N
H
S
L
K
A
M
P
L
P
Site 45
S709
N
N
R
A
D
P
A
S
S
D
H
T
T
R
L
Site 46
T713
D
P
A
S
S
D
H
T
T
R
L
Q
P
L
G
Site 47
T714
P
A
S
S
D
H
T
T
R
L
Q
P
L
G
L
Site 48
S723
L
Q
P
L
G
L
V
S
D
P
S
E
Q
E
V
Site 49
S726
L
G
L
V
S
D
P
S
E
Q
E
V
N
E
L
Site 50
S736
E
V
N
E
L
C
Q
S
V
Q
E
H
V
E
L
Site 51
S781
P
I
L
Y
E
A
G
S
S
P
S
H
H
W
Q
Site 52
S782
I
L
Y
E
A
G
S
S
P
S
H
H
W
Q
L
Site 53
S784
Y
E
A
G
S
S
P
S
H
H
W
Q
L
G
Q
Site 54
T812
R
Q
D
I
Q
D
F
T
Q
A
T
L
D
T
A
Site 55
T818
F
T
Q
A
T
L
D
T
A
R
S
L
C
P
Q
Site 56
S821
A
T
L
D
T
A
R
S
L
C
P
Q
M
L
Q
Site 57
S830
C
P
Q
M
L
Q
G
S
S
W
R
E
Q
L
E
Site 58
S831
P
Q
M
L
Q
G
S
S
W
R
E
Q
L
E
G
Site 59
T860
Q
L
L
Q
D
A
F
T
R
L
R
D
M
R
L
Site 60
S868
R
L
R
D
M
R
L
S
I
T
G
T
L
A
E
Site 61
S895
A
R
D
Q
L
V
E
S
L
A
Q
Q
A
T
V
Site 62
S917
A
P
D
G
G
E
P
S
L
L
E
P
G
E
L
Site 63
S942
E
E
K
E
K
D
D
S
P
P
Q
K
W
P
E
Site 64
S951
P
Q
K
W
P
E
L
S
H
G
L
H
L
V
P
Site 65
S987
A
E
P
Q
A
G
P
S
A
R
G
S
P
S
P
Site 66
S991
A
G
P
S
A
R
G
S
P
S
P
A
A
P
G
Site 67
S993
P
S
A
R
G
S
P
S
P
A
A
P
G
P
P
Site 68
T1020
G
Q
P
L
R
H
P
T
R
A
R
P
R
P
R
Site 69
S1053
P
Q
E
G
N
G
L
S
A
R
V
D
E
G
V
Site 70
S1065
E
G
V
E
E
F
F
S
K
R
L
I
Q
Q
D
Site 71
T1083
A
P
E
E
D
P
A
T
E
G
G
A
T
P
V
Site 72
T1088
P
A
T
E
G
G
A
T
P
V
P
R
T
L
R
Site 73
T1093
G
A
T
P
V
P
R
T
L
R
K
K
L
G
T
Site 74
T1100
T
L
R
K
K
L
G
T
L
F
A
F
K
K
P
Site 75
S1109
F
A
F
K
K
P
R
S
T
R
G
P
R
T
D
Site 76
T1110
A
F
K
K
P
R
S
T
R
G
P
R
T
D
L
Site 77
T1115
R
S
T
R
G
P
R
T
D
L
E
T
S
P
G
Site 78
T1119
G
P
R
T
D
L
E
T
S
P
G
A
A
P
R
Site 79
S1120
P
R
T
D
L
E
T
S
P
G
A
A
P
R
T
Site 80
T1130
A
A
P
R
T
R
K
T
T
F
G
D
L
L
R
Site 81
T1131
A
P
R
T
R
K
T
T
F
G
D
L
L
R
P
Site 82
T1140
G
D
L
L
R
P
P
T
R
P
S
R
G
E
E
Site 83
S1143
L
R
P
P
T
R
P
S
R
G
E
E
L
G
G
Site 84
T1155
L
G
G
A
E
G
D
T
S
S
P
D
P
A
G
Site 85
S1156
G
G
A
E
G
D
T
S
S
P
D
P
A
G
R
Site 86
S1157
G
A
E
G
D
T
S
S
P
D
P
A
G
R
S
Site 87
S1164
S
P
D
P
A
G
R
S
R
P
R
Y
T
R
D
Site 88
Y1168
A
G
R
S
R
P
R
Y
T
R
D
S
K
A
Y
Site 89
T1169
G
R
S
R
P
R
Y
T
R
D
S
K
A
Y
S
Site 90
S1172
R
P
R
Y
T
R
D
S
K
A
Y
S
M
I
L
Site 91
Y1175
Y
T
R
D
S
K
A
Y
S
M
I
L
L
P
A
Site 92
S1176
T
R
D
S
K
A
Y
S
M
I
L
L
P
A
E
Site 93
T1187
L
P
A
E
E
E
A
T
L
G
A
R
P
D
K
Site 94
T1203
R
P
L
E
R
G
E
T
E
L
A
P
S
F
E
Site 95
S1208
G
E
T
E
L
A
P
S
F
E
Q
R
V
Q
V
Site 96
S1226
R
I
G
V
S
R
G
S
G
G
A
E
G
K
R
Site 97
S1236
A
E
G
K
R
K
Q
S
K
D
G
E
I
K
K
Site 98
S1246
G
E
I
K
K
A
G
S
D
G
D
I
M
D
S
Site 99
S1253
S
D
G
D
I
M
D
S
S
T
E
A
P
P
I
Site 100
S1254
D
G
D
I
M
D
S
S
T
E
A
P
P
I
S
Site 101
T1255
G
D
I
M
D
S
S
T
E
A
P
P
I
S
I
Site 102
S1261
S
T
E
A
P
P
I
S
I
K
S
R
T
H
S
Site 103
S1264
A
P
P
I
S
I
K
S
R
T
H
S
V
S
A
Site 104
T1266
P
I
S
I
K
S
R
T
H
S
V
S
A
D
P
Site 105
S1268
S
I
K
S
R
T
H
S
V
S
A
D
P
S
C
Site 106
S1270
K
S
R
T
H
S
V
S
A
D
P
S
C
R
P
Site 107
S1274
H
S
V
S
A
D
P
S
C
R
P
G
P
G
S
Site 108
S1281
S
C
R
P
G
P
G
S
Q
G
P
E
S
A
T
Site 109
S1286
P
G
S
Q
G
P
E
S
A
T
W
K
T
L
G
Site 110
T1291
P
E
S
A
T
W
K
T
L
G
Q
Q
L
N
A
Site 111
S1315
Q
D
G
P
G
P
P
S
P
G
Q
S
P
S
P
Site 112
S1319
G
P
P
S
P
G
Q
S
P
S
P
C
R
T
S
Site 113
S1321
P
S
P
G
Q
S
P
S
P
C
R
T
S
P
S
Site 114
T1325
Q
S
P
S
P
C
R
T
S
P
S
P
D
S
L
Site 115
S1326
S
P
S
P
C
R
T
S
P
S
P
D
S
L
G
Site 116
S1328
S
P
C
R
T
S
P
S
P
D
S
L
G
L
P
Site 117
S1331
R
T
S
P
S
P
D
S
L
G
L
P
E
D
P
Site 118
S1355
Q
L
R
P
R
P
L
S
A
G
R
R
A
V
S
Site 119
S1362
S
A
G
R
R
A
V
S
V
H
E
D
Q
L
Q
Site 120
S1381
R
P
L
R
L
Q
R
S
P
V
L
K
R
R
P
Site 121
S1395
P
K
L
E
A
P
P
S
P
S
L
G
S
G
L
Site 122
S1397
L
E
A
P
P
S
P
S
L
G
S
G
L
G
T
Site 123
T1404
S
L
G
S
G
L
G
T
E
P
L
P
P
Q
P
Site 124
T1412
E
P
L
P
P
Q
P
T
E
P
S
S
P
E
R
Site 125
S1415
P
P
Q
P
T
E
P
S
S
P
E
R
S
P
P
Site 126
S1416
P
Q
P
T
E
P
S
S
P
E
R
S
P
P
S
Site 127
S1420
E
P
S
S
P
E
R
S
P
P
S
P
A
T
D
Site 128
S1423
S
P
E
R
S
P
P
S
P
A
T
D
Q
R
G
Site 129
T1426
R
S
P
P
S
P
A
T
D
Q
R
G
G
G
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation