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Updated November 2019
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Protein Info
Short Name:
UHRF1BP1
Full Name:
UHRF1-binding protein 1
Alias:
CG31653-PA-like; ICBP90 binding 1; Ubiquitin-like containing PHD and RING finger domains 1-binding 1; Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1; URFB1
Type:
Uncharacterized protein
Mass (Da):
159485
Number AA:
1440
UniProt ID:
Q6BDS2
International Prot ID:
IPI00465273
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
K
Q
I
L
K
H
L
S
R
F
T
K
N
L
S
Site 2
T17
L
K
H
L
S
R
F
T
K
N
L
S
P
D
K
Site 3
S21
S
R
F
T
K
N
L
S
P
D
K
I
N
L
S
Site 4
S28
S
P
D
K
I
N
L
S
T
L
K
G
E
G
Q
Site 5
T29
P
D
K
I
N
L
S
T
L
K
G
E
G
Q
L
Site 6
T37
L
K
G
E
G
Q
L
T
N
L
E
L
D
E
E
Site 7
S104
P
R
P
P
N
G
Q
S
P
I
A
L
A
S
G
Site 8
S110
Q
S
P
I
A
L
A
S
G
Q
S
E
Y
G
F
Site 9
S113
I
A
L
A
S
G
Q
S
E
Y
G
F
A
E
K
Site 10
S162
V
N
P
N
W
Q
Q
S
D
L
R
L
T
R
I
Site 11
T167
Q
Q
S
D
L
R
L
T
R
I
T
D
P
C
R
Site 12
T170
D
L
R
L
T
R
I
T
D
P
C
R
G
E
V
Site 13
T179
P
C
R
G
E
V
L
T
F
K
E
I
T
W
Q
Site 14
T195
L
R
I
E
A
D
A
T
D
N
G
D
Q
D
P
Site 15
T204
N
G
D
Q
D
P
V
T
T
P
L
R
L
I
T
Site 16
T205
G
D
Q
D
P
V
T
T
P
L
R
L
I
T
N
Site 17
T211
T
T
P
L
R
L
I
T
N
Q
G
R
I
Q
I
Site 18
T224
Q
I
A
L
K
R
R
T
K
D
C
N
V
I
S
Site 19
Y256
Q
L
K
A
M
M
K
Y
A
E
S
L
S
E
A
Site 20
S259
A
M
M
K
Y
A
E
S
L
S
E
A
M
E
K
Site 21
S261
M
K
Y
A
E
S
L
S
E
A
M
E
K
S
A
Site 22
S267
L
S
E
A
M
E
K
S
A
H
Q
R
K
S
L
Site 23
S273
K
S
A
H
Q
R
K
S
L
A
P
E
P
V
Q
Site 24
T282
A
P
E
P
V
Q
I
T
P
P
A
P
S
A
Q
Site 25
S287
Q
I
T
P
P
A
P
S
A
Q
Q
S
W
A
Q
Site 26
S291
P
A
P
S
A
Q
Q
S
W
A
Q
A
F
G
G
Site 27
S299
W
A
Q
A
F
G
G
S
Q
G
N
S
N
S
S
Site 28
S303
F
G
G
S
Q
G
N
S
N
S
S
S
S
R
L
Site 29
S305
G
S
Q
G
N
S
N
S
S
S
S
R
L
S
Q
Site 30
S306
S
Q
G
N
S
N
S
S
S
S
R
L
S
Q
Y
Site 31
S307
Q
G
N
S
N
S
S
S
S
R
L
S
Q
Y
F
Site 32
S311
N
S
S
S
S
R
L
S
Q
Y
F
E
K
F
D
Site 33
Y313
S
S
S
R
L
S
Q
Y
F
E
K
F
D
V
K
Site 34
S323
K
F
D
V
K
E
S
S
Y
H
L
L
I
S
R
Site 35
S339
D
L
H
I
C
D
D
S
Q
S
R
E
P
G
V
Site 36
S341
H
I
C
D
D
S
Q
S
R
E
P
G
V
S
A
Site 37
S347
Q
S
R
E
P
G
V
S
A
N
R
L
M
G
G
Site 38
S424
P
W
H
L
G
V
D
S
L
F
R
R
K
A
D
Site 39
S432
L
F
R
R
K
A
D
S
L
S
S
P
R
K
N
Site 40
S434
R
R
K
A
D
S
L
S
S
P
R
K
N
P
L
Site 41
S435
R
K
A
D
S
L
S
S
P
R
K
N
P
L
E
Site 42
S444
R
K
N
P
L
E
R
S
P
S
Q
G
R
Q
P
Site 43
S446
N
P
L
E
R
S
P
S
Q
G
R
Q
P
A
F
Site 44
S463
P
A
W
N
R
L
R
S
S
C
M
V
V
R
V
Site 45
S479
D
L
D
I
H
Q
V
S
T
A
G
Q
P
S
K
Site 46
T480
L
D
I
H
Q
V
S
T
A
G
Q
P
S
K
K
Site 47
S485
V
S
T
A
G
Q
P
S
K
K
P
S
T
L
L
Site 48
S489
G
Q
P
S
K
K
P
S
T
L
L
S
C
S
R
Site 49
T490
Q
P
S
K
K
P
S
T
L
L
S
C
S
R
K
Site 50
S493
K
K
P
S
T
L
L
S
C
S
R
K
L
H
N
Site 51
T503
R
K
L
H
N
L
P
T
Q
V
S
A
I
H
I
Site 52
Y515
I
H
I
E
F
T
E
Y
Y
F
P
D
N
Q
E
Site 53
Y516
H
I
E
F
T
E
Y
Y
F
P
D
N
Q
E
L
Site 54
Y557
N
L
F
C
L
D
L
Y
R
S
L
E
Q
F
K
Site 55
S572
A
I
Y
K
L
E
D
S
S
Q
K
D
E
H
L
Site 56
S573
I
Y
K
L
E
D
S
S
Q
K
D
E
H
L
D
Site 57
S591
D
A
F
W
L
K
V
S
F
P
L
E
K
R
E
Site 58
S627
T
R
H
A
P
H
C
S
C
S
D
L
Q
S
L
Site 59
S629
H
A
P
H
C
S
C
S
D
L
Q
S
L
F
R
Site 60
T681
S
C
L
P
Q
P
N
T
L
P
P
Q
R
P
K
Site 61
T699
D
L
W
S
V
H
F
T
Q
I
S
L
D
F
E
Site 62
S702
S
V
H
F
T
Q
I
S
L
D
F
E
G
T
E
Site 63
T708
I
S
L
D
F
E
G
T
E
N
F
K
G
H
T
Site 64
S753
S
E
G
R
L
K
P
S
A
S
F
G
S
P
V
Site 65
S755
G
R
L
K
P
S
A
S
F
G
S
P
V
Q
S
Site 66
S758
K
P
S
A
S
F
G
S
P
V
Q
S
E
A
L
Site 67
S762
S
F
G
S
P
V
Q
S
E
A
L
A
P
D
S
Site 68
S769
S
E
A
L
A
P
D
S
M
S
H
P
R
S
K
Site 69
S771
A
L
A
P
D
S
M
S
H
P
R
S
K
T
E
Site 70
S775
D
S
M
S
H
P
R
S
K
T
E
H
D
L
K
Site 71
T777
M
S
H
P
R
S
K
T
E
H
D
L
K
S
L
Site 72
S783
K
T
E
H
D
L
K
S
L
S
G
L
T
E
V
Site 73
S785
E
H
D
L
K
S
L
S
G
L
T
E
V
M
E
Site 74
S799
E
I
L
K
E
G
S
S
G
M
D
N
K
G
P
Site 75
S822
D
V
H
M
L
V
H
S
P
A
H
V
R
V
R
Site 76
Y833
V
R
V
R
L
D
H
Y
Q
Y
L
A
L
L
R
Site 77
Y835
V
R
L
D
H
Y
Q
Y
L
A
L
L
R
L
K
Site 78
T853
Q
R
L
Q
E
Q
L
T
K
D
T
E
S
M
T
Site 79
T856
Q
E
Q
L
T
K
D
T
E
S
M
T
G
S
P
Site 80
S858
Q
L
T
K
D
T
E
S
M
T
G
S
P
L
Q
Site 81
T860
T
K
D
T
E
S
M
T
G
S
P
L
Q
N
Q
Site 82
S862
D
T
E
S
M
T
G
S
P
L
Q
N
Q
T
A
Site 83
S895
P
G
A
V
D
A
D
S
A
G
S
D
S
T
S
Site 84
S898
V
D
A
D
S
A
G
S
D
S
T
S
L
V
D
Site 85
S900
A
D
S
A
G
S
D
S
T
S
L
V
D
S
E
Site 86
S902
S
A
G
S
D
S
T
S
L
V
D
S
E
L
S
Site 87
S906
D
S
T
S
L
V
D
S
E
L
S
P
S
E
D
Site 88
S909
S
L
V
D
S
E
L
S
P
S
E
D
R
E
L
Site 89
S911
V
D
S
E
L
S
P
S
E
D
R
E
L
K
S
Site 90
S918
S
E
D
R
E
L
K
S
D
A
S
S
D
Q
G
Site 91
S921
R
E
L
K
S
D
A
S
S
D
Q
G
P
A
S
Site 92
S922
E
L
K
S
D
A
S
S
D
Q
G
P
A
S
P
Site 93
S928
S
S
D
Q
G
P
A
S
P
E
K
V
L
E
E
Site 94
S937
E
K
V
L
E
E
S
S
I
E
N
Q
D
V
S
Site 95
S944
S
I
E
N
Q
D
V
S
Q
E
R
P
H
S
N
Site 96
S950
V
S
Q
E
R
P
H
S
N
G
E
L
Q
D
S
Site 97
S957
S
N
G
E
L
Q
D
S
G
P
L
A
Q
Q
L
Site 98
S974
K
G
H
E
A
V
E
S
L
Q
A
K
K
L
S
Site 99
S981
S
L
Q
A
K
K
L
S
R
T
Q
A
S
S
S
Site 100
T983
Q
A
K
K
L
S
R
T
Q
A
S
S
S
P
A
Site 101
S986
K
L
S
R
T
Q
A
S
S
S
P
A
A
L
K
Site 102
S987
L
S
R
T
Q
A
S
S
S
P
A
A
L
K
P
Site 103
S988
S
R
T
Q
A
S
S
S
P
A
A
L
K
P
P
Site 104
T1000
K
P
P
A
G
R
E
T
A
V
N
G
Q
G
E
Site 105
S1019
K
N
I
E
G
E
L
S
S
A
I
H
M
T
K
Site 106
S1020
N
I
E
G
E
L
S
S
A
I
H
M
T
K
D
Site 107
T1047
T
K
E
A
V
S
L
T
K
D
A
F
S
L
G
Site 108
S1052
S
L
T
K
D
A
F
S
L
G
R
D
R
M
T
Site 109
T1059
S
L
G
R
D
R
M
T
S
T
M
H
K
M
L
Site 110
S1060
L
G
R
D
R
M
T
S
T
M
H
K
M
L
S
Site 111
T1061
G
R
D
R
M
T
S
T
M
H
K
M
L
S
L
Site 112
S1067
S
T
M
H
K
M
L
S
L
P
P
A
K
E
P
Site 113
S1087
E
G
V
A
A
P
V
S
G
G
A
A
R
L
R
Site 114
S1097
A
A
R
L
R
F
F
S
M
K
R
T
V
S
Q
Site 115
T1101
R
F
F
S
M
K
R
T
V
S
Q
Q
S
F
D
Site 116
S1103
F
S
M
K
R
T
V
S
Q
Q
S
F
D
G
V
Site 117
S1106
K
R
T
V
S
Q
Q
S
F
D
G
V
S
L
D
Site 118
S1111
Q
Q
S
F
D
G
V
S
L
D
S
S
G
P
E
Site 119
S1114
F
D
G
V
S
L
D
S
S
G
P
E
D
R
I
Site 120
S1115
D
G
V
S
L
D
S
S
G
P
E
D
R
I
S
Site 121
S1122
S
G
P
E
D
R
I
S
V
D
S
D
G
S
D
Site 122
S1125
E
D
R
I
S
V
D
S
D
G
S
D
S
F
V
Site 123
S1130
V
D
S
D
G
S
D
S
F
V
M
L
L
E
S
Site 124
S1139
V
M
L
L
E
S
E
S
G
P
E
S
V
P
P
Site 125
S1143
E
S
E
S
G
P
E
S
V
P
P
G
S
L
S
Site 126
S1148
P
E
S
V
P
P
G
S
L
S
N
V
S
D
N
Site 127
S1150
S
V
P
P
G
S
L
S
N
V
S
D
N
A
G
Site 128
S1153
P
G
S
L
S
N
V
S
D
N
A
G
V
Q
G
Site 129
S1161
D
N
A
G
V
Q
G
S
P
L
V
N
N
Y
G
Site 130
Y1167
G
S
P
L
V
N
N
Y
G
Q
G
S
P
A
A
Site 131
S1171
V
N
N
Y
G
Q
G
S
P
A
A
N
S
S
V
Site 132
S1176
Q
G
S
P
A
A
N
S
S
V
S
P
S
G
E
Site 133
S1177
G
S
P
A
A
N
S
S
V
S
P
S
G
E
D
Site 134
S1179
P
A
A
N
S
S
V
S
P
S
G
E
D
L
I
Site 135
S1181
A
N
S
S
V
S
P
S
G
E
D
L
I
F
H
Site 136
T1212
E
V
R
G
E
D
L
T
V
A
L
Q
A
E
E
Site 137
T1241
L
H
G
Q
C
P
G
T
C
F
Q
E
S
S
T
Site 138
S1246
P
G
T
C
F
Q
E
S
S
T
L
K
T
G
H
Site 139
S1247
G
T
C
F
Q
E
S
S
T
L
K
T
G
H
I
Site 140
T1251
Q
E
S
S
T
L
K
T
G
H
I
R
P
A
V
Site 141
S1272
G
P
G
A
A
V
H
S
P
L
A
S
Q
N
G
Site 142
S1322
M
Q
I
E
L
L
N
S
S
I
T
L
K
D
D
Site 143
Y1334
K
D
D
I
P
P
I
Y
P
T
S
P
G
P
I
Site 144
S1355
E
H
V
V
L
K
R
S
D
D
G
V
F
H
I
Site 145
S1377
P
S
A
E
V
L
K
S
E
K
R
Q
P
P
K
Site 146
Y1434
L
L
Q
E
I
R
K
Y
N
P
F
F
E
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation