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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PDPK2
Full Name:
Putative 3-phosphoinositide-dependent protein kinase 2
Alias:
Type:
Enzyme - Metabolite kinase
Mass (Da):
44765
Number AA:
396
UniProt ID:
Q6A1A2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0019898
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004674
PhosphoSite+
KinaseNET
Biological Process:
GO:0006468
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
V
R
T
Q
T
E
S
S
T
P
P
G
Site 2
S8
M
V
R
T
Q
T
E
S
S
T
P
P
G
I
P
Site 3
S9
V
R
T
Q
T
E
S
S
T
P
P
G
I
P
G
Site 4
T10
R
T
Q
T
E
S
S
T
P
P
G
I
P
G
G
Site 5
T27
Q
G
P
A
M
D
G
T
A
A
E
P
R
P
G
Site 6
S37
E
P
R
P
G
A
G
S
L
Q
H
A
Q
P
P
Site 7
S78
L
A
R
E
L
A
T
S
R
E
Y
A
I
K
I
Site 8
Y81
E
L
A
T
S
R
E
Y
A
I
K
I
L
E
K
Site 9
Y99
I
K
E
N
K
V
P
Y
V
T
R
E
R
D
V
Site 10
Y119
H
P
F
F
V
K
L
Y
F
T
F
Q
D
D
E
Site 11
T121
F
F
V
K
L
Y
F
T
F
Q
D
D
E
K
L
Site 12
Y129
F
Q
D
D
E
K
L
Y
F
G
L
S
Y
A
K
Site 13
S133
E
K
L
Y
F
G
L
S
Y
A
K
N
G
E
L
Site 14
Y143
K
N
G
E
L
L
K
Y
I
R
K
I
G
S
F
Site 15
S149
K
Y
I
R
K
I
G
S
F
D
E
T
C
T
R
Site 16
T153
K
I
G
S
F
D
E
T
C
T
R
F
Y
T
A
Site 17
Y158
D
E
T
C
T
R
F
Y
T
A
E
I
V
S
A
Site 18
S204
F
G
T
A
K
V
L
S
P
E
S
K
Q
A
R
Site 19
S214
S
K
Q
A
R
A
N
S
F
V
G
T
A
Q
Y
Site 20
T218
R
A
N
S
F
V
G
T
A
Q
Y
V
S
P
E
Site 21
S223
V
G
T
A
Q
Y
V
S
P
E
L
L
T
E
K
Site 22
S231
P
E
L
L
T
E
K
S
A
C
K
S
S
D
L
Site 23
S235
T
E
K
S
A
C
K
S
S
D
L
W
A
L
G
Site 24
Y272
Q
K
I
I
K
L
E
Y
D
F
P
E
K
F
F
Site 25
T295
K
L
L
V
L
D
A
T
K
R
L
G
C
E
E
Site 26
Y306
G
C
E
E
M
E
G
Y
G
P
L
K
A
H
P
Site 27
T327
W
E
N
L
H
Q
Q
T
P
P
K
L
T
A
Y
Site 28
Y334
T
P
P
K
L
T
A
Y
L
P
A
M
S
E
D
Site 29
S339
T
A
Y
L
P
A
M
S
E
D
D
E
D
C
Y
Site 30
Y346
S
E
D
D
E
D
C
Y
G
N
V
S
W
P
G
Site 31
S380
P
D
P
R
V
I
C
S
R
K
G
R
V
S
V
Site 32
S386
C
S
R
K
G
R
V
S
V
P
L
R
Q
A
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation