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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA1429
Full Name:
Protein virilizer homolog
Alias:
DKFZP434I116; FSAP121; Functional spliceosome-associated protein 121; MSTP054; Protein virilizer homolog: Protein virilizer homolog: Protein virilizer homolog: Protein virilizer homolog; VIR; Virilizer
Type:
Unknown function
Mass (Da):
202025
Number AA:
1812
UniProt ID:
Q69YN4
International Prot ID:
IPI00036742
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0008380
GO:0006397
GO:0006397
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
M
E
L
L
F
L
D
T
F
K
H
P
S
A
E
Site 2
S19
L
D
T
F
K
H
P
S
A
E
Q
S
S
H
I
Site 3
S23
K
H
P
S
A
E
Q
S
S
H
I
D
V
V
R
Site 4
Y36
V
R
F
P
C
V
V
Y
I
N
E
V
R
V
I
Site 5
S51
P
P
G
V
R
A
H
S
S
L
P
D
N
R
A
Site 6
S52
P
G
V
R
A
H
S
S
L
P
D
N
R
A
Y
Site 7
Y59
S
L
P
D
N
R
A
Y
G
E
T
S
P
H
T
Site 8
S63
N
R
A
Y
G
E
T
S
P
H
T
F
Q
L
D
Site 9
T66
Y
G
E
T
S
P
H
T
F
Q
L
D
L
F
F
Site 10
S89
P
V
F
D
R
L
G
S
L
E
Y
D
E
N
T
Site 11
Y92
D
R
L
G
S
L
E
Y
D
E
N
T
S
I
I
Site 12
T96
S
L
E
Y
D
E
N
T
S
I
I
F
R
P
N
Site 13
S97
L
E
Y
D
E
N
T
S
I
I
F
R
P
N
S
Site 14
S104
S
I
I
F
R
P
N
S
K
V
N
T
D
G
L
Site 15
T108
R
P
N
S
K
V
N
T
D
G
L
V
L
R
G
Site 16
S133
G
S
V
D
R
V
I
S
H
D
R
D
S
P
P
Site 17
S138
V
I
S
H
D
R
D
S
P
P
P
P
P
P
P
Site 18
S154
P
P
P
Q
P
Q
P
S
L
K
R
N
P
K
H
Site 19
S173
K
E
D
Q
F
N
G
S
P
P
R
P
Q
P
R
Site 20
T184
P
Q
P
R
G
P
R
T
P
P
G
P
P
P
P
Site 21
S204
D
P
V
P
L
P
V
S
G
D
K
E
E
D
A
Site 22
Y217
D
A
P
H
R
E
D
Y
F
E
P
I
S
P
D
Site 23
S222
E
D
Y
F
E
P
I
S
P
D
R
N
S
V
P
Site 24
S227
P
I
S
P
D
R
N
S
V
P
Q
E
G
Q
Y
Site 25
S235
V
P
Q
E
G
Q
Y
S
D
E
G
E
V
E
E
Site 26
T270
E
D
E
D
D
R
R
T
V
D
S
I
P
E
E
Site 27
S273
D
D
R
R
T
V
D
S
I
P
E
E
E
E
E
Site 28
Y298
E
G
E
G
D
D
G
Y
E
Q
I
S
S
D
E
Site 29
S303
D
G
Y
E
Q
I
S
S
D
E
D
G
I
A
D
Site 30
T315
I
A
D
L
E
R
E
T
F
K
Y
P
N
F
D
Site 31
Y318
L
E
R
E
T
F
K
Y
P
N
F
D
V
E
Y
Site 32
Y325
Y
P
N
F
D
V
E
Y
T
A
E
D
L
A
S
Site 33
S332
Y
T
A
E
D
L
A
S
V
P
P
M
T
Y
D
Site 34
T337
L
A
S
V
P
P
M
T
Y
D
P
Y
D
R
E
Site 35
Y341
P
P
M
T
Y
D
P
Y
D
R
E
L
V
P
L
Site 36
Y355
L
L
Y
F
S
C
P
Y
K
T
T
F
E
I
E
Site 37
T357
Y
F
S
C
P
Y
K
T
T
F
E
I
E
I
S
Site 38
T358
F
S
C
P
Y
K
T
T
F
E
I
E
I
S
R
Site 39
S364
T
T
F
E
I
E
I
S
R
M
K
D
Q
G
P
Site 40
Y392
L
T
E
L
L
D
L
Y
R
E
D
R
G
A
K
Site 41
S416
S
L
I
I
K
G
L
S
Y
L
Q
L
K
N
T
Site 42
T423
S
Y
L
Q
L
K
N
T
K
Q
D
S
L
G
Q
Site 43
S427
L
K
N
T
K
Q
D
S
L
G
Q
L
V
D
W
Site 44
S498
F
A
D
H
V
S
S
S
L
K
L
N
A
F
K
Site 45
S529
R
G
R
Q
N
E
K
S
G
Y
Q
K
L
L
E
Site 46
Y531
R
Q
N
E
K
S
G
Y
Q
K
L
L
E
L
I
Site 47
S578
D
H
L
A
E
K
T
S
S
L
P
N
H
S
E
Site 48
S579
H
L
A
E
K
T
S
S
L
P
N
H
S
E
P
Site 49
S584
T
S
S
L
P
N
H
S
E
P
D
H
D
T
D
Site 50
T590
H
S
E
P
D
H
D
T
D
A
G
L
E
R
T
Site 51
Y601
L
E
R
T
N
P
E
Y
E
N
E
V
E
A
S
Site 52
S608
Y
E
N
E
V
E
A
S
M
D
M
D
L
L
E
Site 53
S616
M
D
M
D
L
L
E
S
S
N
I
S
E
G
E
Site 54
S617
D
M
D
L
L
E
S
S
N
I
S
E
G
E
I
Site 55
S620
L
L
E
S
S
N
I
S
E
G
E
I
E
R
L
Site 56
T644
L
M
E
T
A
P
H
T
M
I
Q
Q
P
V
K
Site 57
T660
F
P
T
M
A
R
I
T
G
P
P
E
R
D
D
Site 58
Y669
P
P
E
R
D
D
P
Y
P
V
L
F
R
Y
L
Site 59
Y675
P
Y
P
V
L
F
R
Y
L
H
S
H
H
F
L
Site 60
S749
D
E
E
E
G
L
Q
S
D
G
V
I
D
D
A
Site 61
T782
F
S
H
F
Q
R
C
T
A
S
E
E
T
D
H
Site 62
S784
H
F
Q
R
C
T
A
S
E
E
T
D
H
S
D
Site 63
S790
A
S
E
E
T
D
H
S
D
L
L
G
T
L
H
Site 64
S817
S
A
V
G
H
V
F
S
L
E
K
N
L
Q
S
Site 65
S824
S
L
E
K
N
L
Q
S
L
I
T
L
M
E
Y
Site 66
T827
K
N
L
Q
S
L
I
T
L
M
E
Y
Y
S
K
Site 67
S833
I
T
L
M
E
Y
Y
S
K
E
A
L
G
D
S
Site 68
S840
S
K
E
A
L
G
D
S
K
S
K
K
S
V
A
Site 69
S842
E
A
L
G
D
S
K
S
K
K
S
V
A
Y
N
Site 70
S845
G
D
S
K
S
K
K
S
V
A
Y
N
Y
A
C
Site 71
Y914
C
I
P
N
L
I
E
Y
V
K
Q
N
I
D
N
Site 72
T924
Q
N
I
D
N
L
M
T
P
E
G
V
G
L
T
Site 73
T971
F
S
A
E
G
M
D
T
F
I
R
V
L
Q
K
Site 74
S981
R
V
L
Q
K
L
N
S
I
L
T
Q
P
W
R
Site 75
T984
Q
K
L
N
S
I
L
T
Q
P
W
R
L
H
V
Site 76
S1025
T
E
L
L
R
G
G
S
F
E
F
K
D
M
R
Site 77
S1050
L
L
C
S
I
P
L
S
G
R
L
D
S
D
E
Site 78
S1055
P
L
S
G
R
L
D
S
D
E
Q
K
I
Q
N
Site 79
T1080
Q
G
V
N
E
K
L
T
I
S
E
E
T
L
A
Site 80
S1082
V
N
E
K
L
T
I
S
E
E
T
L
A
N
N
Site 81
T1129
L
P
L
P
M
Q
T
T
Q
V
I
E
P
H
D
Site 82
S1138
V
I
E
P
H
D
I
S
V
A
L
N
T
R
K
Site 83
S1166
Q
E
I
V
R
S
F
S
G
T
T
C
Q
P
I
Site 84
T1168
I
V
R
S
F
S
G
T
T
C
Q
P
I
Q
H
Site 85
S1209
L
I
V
E
D
L
Q
S
T
S
E
D
K
E
K
Site 86
S1211
V
E
D
L
Q
S
T
S
E
D
K
E
K
Q
Y
Site 87
Y1218
S
E
D
K
E
K
Q
Y
T
S
Q
T
T
R
L
Site 88
T1219
E
D
K
E
K
Q
Y
T
S
Q
T
T
R
L
L
Site 89
S1220
D
K
E
K
Q
Y
T
S
Q
T
T
R
L
L
A
Site 90
Y1256
T
I
K
G
D
E
R
Y
A
E
I
F
Q
D
L
Site 91
S1273
L
V
R
S
P
G
D
S
V
I
R
Q
Q
C
V
Site 92
Y1282
I
R
Q
Q
C
V
E
Y
V
T
S
I
L
Q
S
Site 93
S1306
L
P
S
S
S
E
G
S
I
S
E
L
E
Q
L
Site 94
S1308
S
S
S
E
G
S
I
S
E
L
E
Q
L
S
N
Site 95
S1314
I
S
E
L
E
Q
L
S
N
S
L
P
N
K
E
Site 96
S1316
E
L
E
Q
L
S
N
S
L
P
N
K
E
L
M
Site 97
S1339
A
T
L
A
N
S
E
S
S
Y
N
C
L
L
T
Site 98
S1340
T
L
A
N
S
E
S
S
Y
N
C
L
L
T
C
Site 99
Y1359
M
F
L
A
E
H
D
Y
G
L
F
H
L
K
S
Site 100
S1366
Y
G
L
F
H
L
K
S
S
L
R
K
N
S
S
Site 101
S1367
G
L
F
H
L
K
S
S
L
R
K
N
S
S
A
Site 102
S1372
K
S
S
L
R
K
N
S
S
A
L
H
S
L
L
Site 103
S1373
S
S
L
R
K
N
S
S
A
L
H
S
L
L
K
Site 104
S1377
K
N
S
S
A
L
H
S
L
L
K
R
V
V
S
Site 105
S1384
S
L
L
K
R
V
V
S
T
F
S
K
D
T
G
Site 106
T1385
L
L
K
R
V
V
S
T
F
S
K
D
T
G
E
Site 107
S1396
D
T
G
E
L
A
S
S
F
L
E
F
M
R
Q
Site 108
T1427
M
E
V
E
G
A
H
T
S
R
T
M
S
I
N
Site 109
S1428
E
V
E
G
A
H
T
S
R
T
M
S
I
N
A
Site 110
S1432
A
H
T
S
R
T
M
S
I
N
A
A
E
L
K
Site 111
S1444
E
L
K
Q
L
L
Q
S
K
E
E
S
P
E
N
Site 112
S1448
L
L
Q
S
K
E
E
S
P
E
N
L
F
L
E
Site 113
S1464
E
K
L
V
L
E
H
S
K
D
D
D
N
L
D
Site 114
S1472
K
D
D
D
N
L
D
S
L
L
D
S
V
V
G
Site 115
S1486
G
L
K
Q
M
L
E
S
S
G
D
P
L
P
L
Site 116
S1487
L
K
Q
M
L
E
S
S
G
D
P
L
P
L
S
Site 117
S1494
S
G
D
P
L
P
L
S
D
Q
D
V
E
P
V
Site 118
S1503
Q
D
V
E
P
V
L
S
A
P
E
S
L
Q
N
Site 119
S1507
P
V
L
S
A
P
E
S
L
Q
N
L
F
N
N
Site 120
T1534
Q
L
K
S
M
W
F
T
P
F
Q
A
E
E
I
Site 121
T1543
F
Q
A
E
E
I
D
T
D
L
D
L
V
K
V
Site 122
S1556
K
V
D
L
I
E
L
S
E
K
C
C
S
D
F
Site 123
S1561
E
L
S
E
K
C
C
S
D
F
D
L
H
S
E
Site 124
S1567
C
S
D
F
D
L
H
S
E
L
E
R
S
F
L
Site 125
S1572
L
H
S
E
L
E
R
S
F
L
S
E
P
S
S
Site 126
S1575
E
L
E
R
S
F
L
S
E
P
S
S
P
G
R
Site 127
S1578
R
S
F
L
S
E
P
S
S
P
G
R
T
K
T
Site 128
S1579
S
F
L
S
E
P
S
S
P
G
R
T
K
T
T
Site 129
T1583
E
P
S
S
P
G
R
T
K
T
T
K
G
F
K
Site 130
T1585
S
S
P
G
R
T
K
T
T
K
G
F
K
L
G
Site 131
T1598
L
G
K
H
K
H
E
T
F
I
T
S
S
G
K
Site 132
T1601
H
K
H
E
T
F
I
T
S
S
G
K
S
E
Y
Site 133
S1602
K
H
E
T
F
I
T
S
S
G
K
S
E
Y
I
Site 134
S1606
F
I
T
S
S
G
K
S
E
Y
I
E
P
A
K
Site 135
Y1608
T
S
S
G
K
S
E
Y
I
E
P
A
K
R
A
Site 136
T1646
F
R
Q
R
K
Q
N
T
S
R
P
P
S
M
H
Site 137
S1647
R
Q
R
K
Q
N
T
S
R
P
P
S
M
H
V
Site 138
S1651
Q
N
T
S
R
P
P
S
M
H
V
D
D
F
V
Site 139
S1681
P
K
R
P
L
K
V
S
Q
K
I
S
S
R
G
Site 140
S1685
L
K
V
S
Q
K
I
S
S
R
G
G
F
S
G
Site 141
S1686
K
V
S
Q
K
I
S
S
R
G
G
F
S
G
N
Site 142
S1691
I
S
S
R
G
G
F
S
G
N
R
G
G
R
G
Site 143
S1702
G
G
R
G
A
F
H
S
Q
N
R
F
F
T
P
Site 144
T1708
H
S
Q
N
R
F
F
T
P
P
A
S
K
G
N
Site 145
S1712
R
F
F
T
P
P
A
S
K
G
N
Y
S
R
R
Site 146
Y1716
P
P
A
S
K
G
N
Y
S
R
R
E
G
T
R
Site 147
S1717
P
A
S
K
G
N
Y
S
R
R
E
G
T
R
G
Site 148
T1722
N
Y
S
R
R
E
G
T
R
G
S
S
W
S
A
Site 149
S1725
R
R
E
G
T
R
G
S
S
W
S
A
Q
N
T
Site 150
S1726
R
E
G
T
R
G
S
S
W
S
A
Q
N
T
P
Site 151
S1728
G
T
R
G
S
S
W
S
A
Q
N
T
P
R
G
Site 152
T1732
S
S
W
S
A
Q
N
T
P
R
G
N
Y
N
E
Site 153
Y1737
Q
N
T
P
R
G
N
Y
N
E
S
R
G
G
Q
Site 154
S1759
L
P
P
L
R
P
L
S
S
T
G
Y
R
P
S
Site 155
S1760
P
P
L
R
P
L
S
S
T
G
Y
R
P
S
P
Site 156
T1761
P
L
R
P
L
S
S
T
G
Y
R
P
S
P
R
Site 157
S1766
S
S
T
G
Y
R
P
S
P
R
D
R
A
S
R
Site 158
S1772
P
S
P
R
D
R
A
S
R
G
R
G
G
L
G
Site 159
S1781
G
R
G
G
L
G
P
S
W
A
S
A
N
S
G
Site 160
S1784
G
L
G
P
S
W
A
S
A
N
S
G
S
G
G
Site 161
S1787
P
S
W
A
S
A
N
S
G
S
G
G
S
R
G
Site 162
S1798
G
S
R
G
K
F
V
S
G
G
S
G
R
G
R
Site 163
S1801
G
K
F
V
S
G
G
S
G
R
G
R
H
V
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation