KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
LHX8
Full Name:
LIM/homeobox protein Lhx8
Alias:
Lhx7; LIM homeobox 8
Type:
Unknown function
Mass (Da):
39270
Number AA:
UniProt ID:
Q68G74
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
S
R
C
Q
G
L
M
S
E
E
C
G
R
T
T
Site 2
T18
M
S
E
E
C
G
R
T
T
A
L
A
A
G
R
Site 3
T19
S
E
E
C
G
R
T
T
A
L
A
A
G
R
T
Site 4
S37
A
G
E
E
G
L
V
S
P
E
G
A
G
D
E
Site 5
S46
E
G
A
G
D
E
D
S
C
S
S
S
A
P
L
Site 6
S48
A
G
D
E
D
S
C
S
S
S
A
P
L
S
P
Site 7
S49
G
D
E
D
S
C
S
S
S
A
P
L
S
P
S
Site 8
S50
D
E
D
S
C
S
S
S
A
P
L
S
P
S
S
Site 9
S54
C
S
S
S
A
P
L
S
P
S
S
S
P
R
S
Site 10
S56
S
S
A
P
L
S
P
S
S
S
P
R
S
M
A
Site 11
S57
S
A
P
L
S
P
S
S
S
P
R
S
M
A
S
Site 12
S58
A
P
L
S
P
S
S
S
P
R
S
M
A
S
G
Site 13
S61
S
P
S
S
S
P
R
S
M
A
S
G
S
G
C
Site 14
S64
S
S
P
R
S
M
A
S
G
S
G
C
P
P
G
Site 15
S66
P
R
S
M
A
S
G
S
G
C
P
P
G
K
C
Site 16
T107
L
S
C
S
V
C
R
T
S
L
G
R
H
T
S
Site 17
S108
S
C
S
V
C
R
T
S
L
G
R
H
T
S
C
Site 18
T113
R
T
S
L
G
R
H
T
S
C
Y
I
K
D
K
Site 19
S114
T
S
L
G
R
H
T
S
C
Y
I
K
D
K
D
Site 20
Y116
L
G
R
H
T
S
C
Y
I
K
D
K
D
I
F
Site 21
Y128
D
I
F
C
K
L
D
Y
F
R
R
Y
G
T
R
Site 22
Y132
K
L
D
Y
F
R
R
Y
G
T
R
C
S
R
C
Site 23
Y157
R
R
A
K
G
N
V
Y
H
L
A
C
F
A
C
Site 24
S172
F
S
C
K
R
Q
L
S
T
G
E
E
F
A
L
Site 25
T215
S
V
E
G
A
L
L
T
E
Q
D
V
N
H
P
Site 26
T230
K
P
A
K
R
A
R
T
S
F
T
A
D
Q
L
Site 27
S231
P
A
K
R
A
R
T
S
F
T
A
D
Q
L
Q
Site 28
S265
L
A
E
R
T
G
L
S
R
R
V
I
Q
V
W
Site 29
S285
A
R
H
K
K
H
V
S
P
N
H
S
S
S
T
Site 30
S289
K
H
V
S
P
N
H
S
S
S
T
P
V
T
A
Site 31
S290
H
V
S
P
N
H
S
S
S
T
P
V
T
A
A
Site 32
S291
V
S
P
N
H
S
S
S
T
P
V
T
A
A
P
Site 33
T292
S
P
N
H
S
S
S
T
P
V
T
A
A
P
P
Site 34
T295
H
S
S
S
T
P
V
T
A
A
P
P
S
R
L
Site 35
S303
A
A
P
P
S
R
L
S
P
P
M
L
E
E
M
Site 36
Y312
P
M
L
E
E
M
A
Y
S
A
Y
V
P
Q
D
Site 37
Y315
E
E
M
A
Y
S
A
Y
V
P
Q
D
G
T
M
Site 38
T324
P
Q
D
G
T
M
L
T
A
L
H
S
Y
M
D
Site 39
S328
T
M
L
T
A
L
H
S
Y
M
D
A
H
S
P
Site 40
S334
H
S
Y
M
D
A
H
S
P
T
T
L
G
L
Q
Site 41
T349
P
L
L
P
H
S
M
T
Q
L
P
I
S
H
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation