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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLA2G4F
Full Name:
Cytosolic phospholipase A2 zeta
Alias:
Phospholipase A2 group IVF
Type:
Mass (Da):
95050
Number AA:
849
UniProt ID:
Q68DD2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y41
R
H
W
R
R
E
T
Y
P
Y
Y
D
L
Q
V
Site 2
Y43
W
R
R
E
T
Y
P
Y
Y
D
L
Q
V
K
V
Site 3
Y44
R
R
E
T
Y
P
Y
Y
D
L
Q
V
K
V
L
Site 4
T54
Q
V
K
V
L
R
A
T
N
I
R
G
T
D
L
Site 5
T59
R
A
T
N
I
R
G
T
D
L
L
S
K
A
D
Site 6
S63
I
R
G
T
D
L
L
S
K
A
D
C
Y
V
Q
Site 7
T75
Y
V
Q
L
W
L
P
T
A
S
P
S
P
A
Q
Site 8
S77
Q
L
W
L
P
T
A
S
P
S
P
A
Q
T
R
Site 9
S79
W
L
P
T
A
S
P
S
P
A
Q
T
R
I
V
Site 10
T83
A
S
P
S
P
A
Q
T
R
I
V
A
N
C
S
Site 11
S90
T
R
I
V
A
N
C
S
D
P
E
W
N
E
T
Site 12
S152
F
P
L
N
H
Q
D
S
Q
E
L
Q
V
E
F
Site 13
S169
E
K
S
Q
V
P
A
S
E
V
I
T
N
G
V
Site 14
T188
P
C
L
R
I
Q
G
T
L
R
G
D
G
T
A
Site 15
T194
G
T
L
R
G
D
G
T
A
P
R
E
E
Y
G
Site 16
Y200
G
T
A
P
R
E
E
Y
G
S
R
Q
L
Q
L
Site 17
S202
A
P
R
E
E
Y
G
S
R
Q
L
Q
L
A
V
Site 18
Y213
Q
L
A
V
P
G
A
Y
E
K
P
Q
L
L
P
Site 19
T225
L
L
P
L
Q
P
P
T
E
P
G
L
P
P
T
Site 20
T232
T
E
P
G
L
P
P
T
F
T
F
H
V
N
P
Site 21
S269
A
E
L
E
A
Q
T
S
K
L
G
E
G
G
I
Site 22
S280
E
G
G
I
L
L
S
S
L
P
L
G
Q
E
E
Site 23
S290
L
G
Q
E
E
Q
C
S
V
A
L
G
E
G
Q
Site 24
S302
E
G
Q
E
V
A
L
S
M
K
V
E
M
S
S
Site 25
S308
L
S
M
K
V
E
M
S
S
G
D
L
D
L
R
Site 26
S321
L
R
L
G
F
D
L
S
D
G
E
Q
E
F
L
Site 27
S336
D
R
R
K
Q
V
V
S
K
A
L
Q
Q
V
L
Site 28
S346
L
Q
Q
V
L
G
L
S
E
A
L
D
S
G
Q
Site 29
S370
G
G
G
T
R
A
M
S
S
L
Y
G
S
L
A
Site 30
S371
G
G
T
R
A
M
S
S
L
Y
G
S
L
A
G
Site 31
S411
L
Y
R
D
P
A
W
S
Q
V
A
L
Q
G
P
Site 32
S435
S
S
K
M
G
A
L
S
T
E
R
L
Q
Y
Y
Site 33
T436
S
K
M
G
A
L
S
T
E
R
L
Q
Y
Y
T
Site 34
Y441
L
S
T
E
R
L
Q
Y
Y
T
Q
E
L
G
V
Site 35
Y442
S
T
E
R
L
Q
Y
Y
T
Q
E
L
G
V
R
Site 36
T443
T
E
R
L
Q
Y
Y
T
Q
E
L
G
V
R
E
Site 37
S452
E
L
G
V
R
E
R
S
G
H
S
V
S
L
I
Site 38
S457
E
R
S
G
H
S
V
S
L
I
D
L
W
G
L
Site 39
Y471
L
L
V
E
Y
L
L
Y
Q
E
E
N
P
A
K
Site 40
S480
E
E
N
P
A
K
L
S
D
Q
Q
E
A
V
R
Site 41
Y493
V
R
Q
G
Q
N
P
Y
P
I
Y
T
S
V
N
Site 42
Y496
G
Q
N
P
Y
P
I
Y
T
S
V
N
V
R
T
Site 43
S506
V
N
V
R
T
N
L
S
G
E
D
F
A
E
W
Site 44
Y519
E
W
C
E
F
T
P
Y
E
V
G
F
P
K
Y
Site 45
Y526
Y
E
V
G
F
P
K
Y
G
A
Y
V
P
T
E
Site 46
Y529
G
F
P
K
Y
G
A
Y
V
P
T
E
L
F
G
Site 47
Y555
Q
P
E
P
R
I
C
Y
L
Q
G
M
W
G
S
Site 48
S581
K
T
A
G
S
G
L
S
F
L
E
W
Y
R
G
Site 49
T593
Y
R
G
S
V
N
I
T
D
D
C
Q
K
P
Q
Site 50
T609
H
N
P
S
R
L
R
T
R
L
L
T
P
Q
G
Site 51
T613
R
L
R
T
R
L
L
T
P
Q
G
P
F
S
Q
Site 52
T631
D
I
F
T
S
R
F
T
S
A
Q
S
F
N
F
Site 53
S632
I
F
T
S
R
F
T
S
A
Q
S
F
N
F
T
Site 54
S635
S
R
F
T
S
A
Q
S
F
N
F
T
R
G
L
Site 55
T639
S
A
Q
S
F
N
F
T
R
G
L
C
L
H
K
Site 56
T670
D
A
F
P
N
Q
L
T
P
M
R
D
C
L
Y
Site 57
Y722
V
L
K
M
T
E
K
Y
C
L
D
R
G
I
P
Site 58
S732
D
R
G
I
P
F
P
S
I
E
V
G
P
E
D
Site 59
Y747
V
E
E
A
R
E
C
Y
L
F
A
K
A
E
D
Site 60
S757
A
K
A
E
D
P
R
S
P
I
V
L
H
F
P
Site 61
T769
H
F
P
L
V
N
R
T
F
R
T
H
L
A
P
Site 62
T782
A
P
G
V
E
R
Q
T
A
E
E
K
A
F
G
Site 63
T798
F
V
I
N
R
P
D
T
P
Y
G
M
M
N
F
Site 64
Y800
I
N
R
P
D
T
P
Y
G
M
M
N
F
T
Y
Site 65
Y807
Y
G
M
M
N
F
T
Y
E
P
Q
D
F
Y
R
Site 66
Y813
T
Y
E
P
Q
D
F
Y
R
L
V
A
L
S
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation