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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ACSM2A
Full Name:
Acyl-coenzyme A synthetase ACSM2B, mitochondrial
Alias:
A-923A4.1; ACS2B; ACSM2; acyl-CoA synthetase medium-chain family member 2A; medium chain acyl-CoA synthetase; MGC150530
Type:
EC 6.2.1.2; Carbohydrate Metabolism - butanoate; Ligase; Mitochondrial
Mass (Da):
64260
Number AA:
UniProt ID:
Q68CK6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005759
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0047760
GO:0000287
PhosphoSite+
KinaseNET
Biological Process:
GO:0006631
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
R
K
V
Q
G
L
C
T
L
W
G
T
Q
M
S
Site 2
Y24
Q
M
S
S
R
T
L
Y
I
N
S
R
Q
L
V
Site 3
S27
S
R
T
L
Y
I
N
S
R
Q
L
V
S
L
Q
Site 4
S66
K
A
G
K
R
L
P
S
P
A
L
W
W
V
N
Site 5
S87
M
W
N
F
R
E
L
S
E
N
S
Q
Q
A
A
Site 6
S142
P
G
T
I
Q
M
K
S
T
D
I
L
Y
R
L
Site 7
Y147
M
K
S
T
D
I
L
Y
R
L
Q
M
S
K
A
Site 8
T169
E
V
I
Q
E
V
D
T
V
A
S
E
C
P
S
Site 9
S172
Q
E
V
D
T
V
A
S
E
C
P
S
L
R
I
Site 10
S187
K
L
L
V
S
E
K
S
C
D
G
W
L
N
F
Site 11
S202
K
K
L
L
N
E
A
S
T
T
H
H
C
V
E
Site 12
T204
L
L
N
E
A
S
T
T
H
H
C
V
E
T
G
Site 13
S212
H
H
C
V
E
T
G
S
Q
E
A
S
A
I
Y
Site 14
S216
E
T
G
S
Q
E
A
S
A
I
Y
F
T
S
G
Site 15
Y219
S
Q
E
A
S
A
I
Y
F
T
S
G
T
S
G
Site 16
S234
L
P
K
M
A
E
H
S
Y
S
S
L
G
L
K
Site 17
Y235
P
K
M
A
E
H
S
Y
S
S
L
G
L
K
A
Site 18
S236
K
M
A
E
H
S
Y
S
S
L
G
L
K
A
K
Site 19
S276
I
L
G
S
L
L
E
S
W
T
L
G
A
C
T
Site 20
T278
G
S
L
L
E
S
W
T
L
G
A
C
T
F
V
Site 21
Y303
I
L
K
T
L
S
S
Y
P
I
K
S
M
M
G
Site 22
S324
M
L
L
Q
Q
D
L
S
S
Y
K
F
P
H
L
Site 23
S325
L
L
Q
Q
D
L
S
S
Y
K
F
P
H
L
Q
Site 24
Y326
L
Q
Q
D
L
S
S
Y
K
F
P
H
L
Q
N
Site 25
T345
G
E
S
L
L
P
E
T
L
E
N
W
R
A
Q
Site 26
T353
L
E
N
W
R
A
Q
T
G
L
D
I
R
E
F
Site 27
Y361
G
L
D
I
R
E
F
Y
G
Q
T
E
T
G
L
Site 28
T369
G
Q
T
E
T
G
L
T
C
M
V
S
K
T
M
Site 29
Y382
T
M
K
I
K
P
G
Y
M
G
T
A
A
S
C
Site 30
T406
G
N
V
L
P
P
G
T
E
G
D
I
G
I
R
Site 31
Y426
P
I
G
I
F
S
G
Y
V
E
N
P
D
K
T
Site 32
T433
Y
V
E
N
P
D
K
T
A
A
N
I
R
G
D
Site 33
Y455
G
I
K
D
E
D
G
Y
F
Q
F
M
G
R
A
Site 34
S469
A
D
D
I
I
N
S
S
G
Y
R
I
G
P
S
Site 35
Y471
D
I
I
N
S
S
G
Y
R
I
G
P
S
E
V
Site 36
T491
K
H
P
A
V
V
E
T
A
V
I
S
S
P
D
Site 37
S496
V
E
T
A
V
I
S
S
P
D
P
V
R
G
E
Site 38
S517
I
L
A
S
Q
F
L
S
H
D
P
E
Q
L
T
Site 39
T524
S
H
D
P
E
Q
L
T
K
E
L
Q
Q
H
V
Site 40
S533
E
L
Q
Q
H
V
K
S
V
T
A
P
Y
K
Y
Site 41
Y538
V
K
S
V
T
A
P
Y
K
Y
P
R
K
I
E
Site 42
Y540
S
V
T
A
P
Y
K
Y
P
R
K
I
E
F
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation