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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBC1D9B
Full Name:
TBC1 domain family member 9B
Alias:
KIAA0676; TBC1 domain family, member 9B (with GRAM domain); TBC9B
Type:
Unknown function
Mass (Da):
140498
Number AA:
1250
UniProt ID:
Q66K14
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005097
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0032313
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T73
Q
D
S
Q
V
Y
W
T
V
A
C
G
S
S
R
Site 2
S78
Y
W
T
V
A
C
G
S
S
R
K
E
I
T
K
Site 3
T97
L
E
N
N
L
L
Q
T
L
S
I
F
D
S
E
Site 4
S99
N
N
L
L
Q
T
L
S
I
F
D
S
E
E
D
Site 5
S103
Q
T
L
S
I
F
D
S
E
E
D
I
T
T
F
Site 6
T108
F
D
S
E
E
D
I
T
T
F
V
K
G
K
I
Site 7
T109
D
S
E
E
D
I
T
T
F
V
K
G
K
I
H
Site 8
Y159
E
G
E
K
L
V
N
Y
Y
S
C
S
Y
W
K
Site 9
Y160
G
E
K
L
V
N
Y
Y
S
C
S
Y
W
K
G
Site 10
T210
T
R
L
E
K
N
A
T
L
L
F
P
E
S
I
Site 11
S216
A
T
L
L
F
P
E
S
I
R
V
D
T
R
D
Site 12
T221
P
E
S
I
R
V
D
T
R
D
Q
E
L
F
F
Site 13
S229
R
D
Q
E
L
F
F
S
M
F
L
N
I
G
E
Site 14
S255
A
M
R
Q
L
L
D
S
E
G
F
L
E
D
K
Site 15
S275
I
R
P
H
R
N
I
S
A
L
K
R
D
L
D
Site 16
T293
K
N
E
C
Y
R
A
T
F
R
L
P
R
D
E
Site 17
T306
D
E
R
L
D
G
H
T
S
C
T
L
W
T
P
Site 18
Y329
Q
M
F
I
S
N
N
Y
I
C
F
A
S
K
E
Site 19
T350
I
I
P
L
R
E
V
T
I
V
E
K
A
D
S
Site 20
S357
T
I
V
E
K
A
D
S
S
S
V
L
P
S
P
Site 21
S359
V
E
K
A
D
S
S
S
V
L
P
S
P
L
S
Site 22
S363
D
S
S
S
V
L
P
S
P
L
S
I
S
T
K
Site 23
S366
S
V
L
P
S
P
L
S
I
S
T
K
S
K
M
Site 24
S368
L
P
S
P
L
S
I
S
T
K
S
K
M
T
F
Site 25
S371
P
L
S
I
S
T
K
S
K
M
T
F
L
F
A
Site 26
T374
I
S
T
K
S
K
M
T
F
L
F
A
N
L
K
Site 27
S391
D
F
L
V
Q
R
I
S
D
F
L
Q
K
T
P
Site 28
T397
I
S
D
F
L
Q
K
T
P
S
K
Q
P
G
S
Site 29
S399
D
F
L
Q
K
T
P
S
K
Q
P
G
S
I
G
Site 30
S404
T
P
S
K
Q
P
G
S
I
G
S
R
K
A
S
Site 31
S407
K
Q
P
G
S
I
G
S
R
K
A
S
V
V
D
Site 32
S411
S
I
G
S
R
K
A
S
V
V
D
P
S
T
E
Site 33
S416
K
A
S
V
V
D
P
S
T
E
S
S
P
A
P
Site 34
T417
A
S
V
V
D
P
S
T
E
S
S
P
A
P
Q
Site 35
S420
V
D
P
S
T
E
S
S
P
A
P
Q
E
G
S
Site 36
S427
S
P
A
P
Q
E
G
S
E
Q
P
A
S
P
A
Site 37
S432
E
G
S
E
Q
P
A
S
P
A
S
P
L
S
S
Site 38
S435
E
Q
P
A
S
P
A
S
P
L
S
S
R
Q
S
Site 39
S438
A
S
P
A
S
P
L
S
S
R
Q
S
F
C
A
Site 40
S439
S
P
A
S
P
L
S
S
R
Q
S
F
C
A
Q
Site 41
S442
S
P
L
S
S
R
Q
S
F
C
A
Q
E
A
P
Site 42
S463
L
K
L
F
Q
K
N
S
P
M
E
D
L
G
A
Site 43
Y496
Y
G
R
G
V
C
M
Y
R
T
A
K
T
R
A
Site 44
S512
V
L
K
G
I
P
E
S
L
R
G
E
L
W
L
Site 45
Y534
E
M
V
T
H
P
G
Y
Y
A
E
L
V
E
K
Site 46
S542
Y
A
E
L
V
E
K
S
T
G
K
Y
S
L
A
Site 47
Y546
V
E
K
S
T
G
K
Y
S
L
A
T
E
E
I
Site 48
S547
E
K
S
T
G
K
Y
S
L
A
T
E
E
I
E
Site 49
S560
I
E
R
D
L
H
R
S
M
P
E
H
P
A
F
Site 50
Y627
C
E
R
M
L
P
D
Y
Y
N
T
R
V
V
G
Site 51
Y628
E
R
M
L
P
D
Y
Y
N
T
R
V
V
G
A
Site 52
T646
Q
G
I
F
E
E
L
T
R
D
F
L
P
Q
L
Site 53
Y730
A
M
T
M
L
G
R
Y
L
D
N
V
V
N
K
Site 54
S739
D
N
V
V
N
K
Q
S
V
S
P
P
I
P
H
Site 55
S741
V
V
N
K
Q
S
V
S
P
P
I
P
H
L
R
Site 56
S752
P
H
L
R
A
L
L
S
S
S
D
D
P
P
A
Site 57
S753
H
L
R
A
L
L
S
S
S
D
D
P
P
A
E
Site 58
S754
L
R
A
L
L
S
S
S
D
D
P
P
A
E
V
Site 59
Y771
F
E
L
L
K
V
S
Y
E
K
F
S
S
L
R
Site 60
S776
V
S
Y
E
K
F
S
S
L
R
A
E
D
I
E
Site 61
S796
Q
R
L
K
V
I
Q
S
L
E
D
T
A
K
R
Site 62
T800
V
I
Q
S
L
E
D
T
A
K
R
S
V
V
R
Site 63
Y824
I
E
E
L
E
D
L
Y
M
V
F
K
A
K
H
Site 64
S834
F
K
A
K
H
L
A
S
Q
Y
W
G
C
S
R
Site 65
Y836
A
K
H
L
A
S
Q
Y
W
G
C
S
R
T
M
Site 66
S850
M
A
G
R
R
D
P
S
L
P
Y
L
E
Q
Y
Site 67
Y853
R
R
D
P
S
L
P
Y
L
E
Q
Y
R
I
D
Site 68
Y857
S
L
P
Y
L
E
Q
Y
R
I
D
A
S
Q
F
Site 69
S862
E
Q
Y
R
I
D
A
S
Q
F
R
E
L
F
A
Site 70
T872
R
E
L
F
A
S
L
T
P
W
A
C
G
S
H
Site 71
S897
L
L
D
E
N
K
D
S
L
I
N
F
K
E
F
Site 72
T917
G
M
Y
H
G
D
L
T
E
K
L
K
V
L
Y
Site 73
S933
L
H
L
P
P
A
L
S
P
E
E
A
E
S
A
Site 74
S939
L
S
P
E
E
A
E
S
A
L
E
A
A
H
Y
Site 75
Y946
S
A
L
E
A
A
H
Y
F
T
E
D
S
S
S
Site 76
T948
L
E
A
A
H
Y
F
T
E
D
S
S
S
E
A
Site 77
S951
A
H
Y
F
T
E
D
S
S
S
E
A
S
P
L
Site 78
S952
H
Y
F
T
E
D
S
S
S
E
A
S
P
L
A
Site 79
S953
Y
F
T
E
D
S
S
S
E
A
S
P
L
A
S
Site 80
S956
E
D
S
S
S
E
A
S
P
L
A
S
D
L
D
Site 81
S982
P
Q
E
E
Q
E
G
S
G
S
E
E
R
G
E
Site 82
S984
E
E
Q
E
G
S
G
S
E
E
R
G
E
E
K
Site 83
T993
E
R
G
E
E
K
G
T
S
S
P
D
Y
R
H
Site 84
S994
R
G
E
E
K
G
T
S
S
P
D
Y
R
H
Y
Site 85
S995
G
E
E
K
G
T
S
S
P
D
Y
R
H
Y
L
Site 86
Y998
K
G
T
S
S
P
D
Y
R
H
Y
L
R
M
W
Site 87
Y1001
S
S
P
D
Y
R
H
Y
L
R
M
W
A
K
E
Site 88
Y1035
I
E
L
C
K
T
L
Y
N
M
F
S
E
D
P
Site 89
S1039
K
T
L
Y
N
M
F
S
E
D
P
M
E
Q
D
Site 90
Y1048
D
P
M
E
Q
D
L
Y
H
A
I
A
T
V
A
Site 91
S1069
G
E
V
G
K
K
F
S
A
R
T
G
R
K
P
Site 92
T1081
R
K
P
R
D
C
A
T
E
E
D
E
P
P
A
Site 93
T1119
G
G
D
T
H
L
G
T
A
P
Q
E
S
Q
V
Site 94
S1124
L
G
T
A
P
Q
E
S
Q
V
V
V
E
G
G
Site 95
S1138
G
S
G
E
G
Q
G
S
P
S
Q
L
L
S
D
Site 96
S1140
G
E
G
Q
G
S
P
S
Q
L
L
S
D
D
E
Site 97
S1144
G
S
P
S
Q
L
L
S
D
D
E
T
K
D
D
Site 98
T1148
Q
L
L
S
D
D
E
T
K
D
D
M
S
M
S
Site 99
S1153
D
E
T
K
D
D
M
S
M
S
S
Y
S
V
V
Site 100
S1155
T
K
D
D
M
S
M
S
S
Y
S
V
V
S
T
Site 101
S1156
K
D
D
M
S
M
S
S
Y
S
V
V
S
T
G
Site 102
Y1157
D
D
M
S
M
S
S
Y
S
V
V
S
T
G
S
Site 103
S1158
D
M
S
M
S
S
Y
S
V
V
S
T
G
S
L
Site 104
T1162
S
S
Y
S
V
V
S
T
G
S
L
Q
C
E
D
Site 105
S1238
K
K
V
E
R
Q
F
S
T
A
S
D
H
E
Q
Site 106
T1239
K
V
E
R
Q
F
S
T
A
S
D
H
E
Q
P
Site 107
S1241
E
R
Q
F
S
T
A
S
D
H
E
Q
P
G
V
Site 108
S1249
D
H
E
Q
P
G
V
S
G
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation