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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STEAP3
Full Name:
Metalloreductase STEAP3
Alias:
Dudlin 2; Dudlin-2; Dudulin 2; Dudulin-2; EC 1.16.1.-; PHyde; Six transmembrane prostate protein 3; Six-transmembrane epithelial antigen of prostate 3; STEA3; STEAP family 3; STMP3; TSAP6; Tumor suppressor pHyde; Tumor suppressor-activated pathway protein 6
Type:
Mass (Da):
54601
Number AA:
488
UniProt ID:
Q658P3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005768
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0050660
GO:0005507
GO:0009055
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0007049
GO:0006826
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
E
M
D
K
P
L
I
S
L
H
L
V
D
S
D
Site 2
S17
I
S
L
H
L
V
D
S
D
S
S
L
A
K
V
Site 3
S19
L
H
L
V
D
S
D
S
S
L
A
K
V
P
D
Site 4
S20
H
L
V
D
S
D
S
S
L
A
K
V
P
D
E
Site 5
S42
G
S
G
D
F
A
R
S
L
A
T
R
L
V
G
Site 6
T64
G
S
R
N
P
K
R
T
A
R
L
F
P
S
A
Site 7
S70
R
T
A
R
L
F
P
S
A
A
Q
V
T
F
Q
Site 8
S97
A
V
F
R
E
H
Y
S
S
L
C
S
L
S
D
Site 9
S98
V
F
R
E
H
Y
S
S
L
C
S
L
S
D
Q
Site 10
S101
E
H
Y
S
S
L
C
S
L
S
D
Q
L
A
G
Site 11
S115
G
K
I
L
V
D
V
S
N
P
T
E
Q
E
H
Site 12
S128
E
H
L
Q
H
R
E
S
N
A
E
Y
L
A
S
Site 13
Y132
H
R
E
S
N
A
E
Y
L
A
S
L
F
P
T
Site 14
T141
A
S
L
F
P
T
C
T
V
V
K
A
F
N
V
Site 15
S179
P
E
A
K
R
A
V
S
E
M
A
L
A
M
G
Site 16
Y227
L
G
L
F
V
C
F
Y
A
Y
N
F
V
R
D
Site 17
Y239
V
R
D
V
L
Q
P
Y
V
Q
E
S
Q
N
K
Site 18
S243
L
Q
P
Y
V
Q
E
S
Q
N
K
F
F
K
L
Site 19
T286
A
L
Q
L
R
R
G
T
K
Y
Q
R
F
P
D
Site 20
Y288
Q
L
R
R
G
T
K
Y
Q
R
F
P
D
W
L
Site 21
Y331
P
L
R
R
A
H
R
Y
D
L
V
N
L
A
V
Site 22
S385
S
L
P
S
I
A
N
S
L
N
W
R
E
F
S
Site 23
S392
S
L
N
W
R
E
F
S
F
V
Q
S
S
L
G
Site 24
Y424
R
A
F
E
E
S
R
Y
K
F
Y
L
P
P
T
Site 25
Y427
E
E
S
R
Y
K
F
Y
L
P
P
T
F
T
L
Site 26
S469
R
R
G
W
E
R
E
S
T
I
K
F
T
L
P
Site 27
T470
R
G
W
E
R
E
S
T
I
K
F
T
L
P
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation