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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FRG2
Full Name:
Protein FRG2
Alias:
FSHD region gene 2 protein
Type:
Mass (Da):
30490
Number AA:
278
UniProt ID:
Q64ET8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
G
K
G
N
E
D
S
D
L
H
C
S
S
I
Site 2
S14
D
S
D
L
H
C
S
S
I
Q
C
S
T
D
Q
Site 3
S28
Q
P
P
F
Q
Q
I
S
F
T
E
K
G
S
D
Site 4
T30
P
F
Q
Q
I
S
F
T
E
K
G
S
D
E
K
Site 5
S34
I
S
F
T
E
K
G
S
D
E
K
K
P
F
K
Site 6
T46
P
F
K
E
K
G
K
T
A
F
S
H
S
S
E
Site 7
S49
E
K
G
K
T
A
F
S
H
S
S
E
K
H
I
Site 8
S51
G
K
T
A
F
S
H
S
S
E
K
H
I
Q
R
Site 9
S61
K
H
I
Q
R
Q
G
S
E
P
N
P
N
K
E
Site 10
S80
T
K
L
K
A
G
N
S
T
A
G
S
E
P
E
Site 11
S84
A
G
N
S
T
A
G
S
E
P
E
S
S
S
Y
Site 12
S88
T
A
G
S
E
P
E
S
S
S
Y
R
E
N
C
Site 13
S89
A
G
S
E
P
E
S
S
S
Y
R
E
N
C
R
Site 14
S90
G
S
E
P
E
S
S
S
Y
R
E
N
C
R
K
Site 15
Y91
S
E
P
E
S
S
S
Y
R
E
N
C
R
K
R
Site 16
S101
N
C
R
K
R
K
M
S
S
K
D
S
C
Q
D
Site 17
S102
C
R
K
R
K
M
S
S
K
D
S
C
Q
D
T
Site 18
S105
R
K
M
S
S
K
D
S
C
Q
D
T
A
G
N
Site 19
T109
S
K
D
S
C
Q
D
T
A
G
N
C
P
E
K
Site 20
S119
N
C
P
E
K
E
C
S
L
S
L
N
K
K
S
Site 21
S121
P
E
K
E
C
S
L
S
L
N
K
K
S
R
S
Site 22
S126
S
L
S
L
N
K
K
S
R
S
S
T
A
V
H
Site 23
S128
S
L
N
K
K
S
R
S
S
T
A
V
H
N
S
Site 24
S129
L
N
K
K
S
R
S
S
T
A
V
H
N
S
E
Site 25
T130
N
K
K
S
R
S
S
T
A
V
H
N
S
E
I
Site 26
S149
D
A
H
H
R
G
H
S
R
A
C
T
G
H
S
Site 27
T153
R
G
H
S
R
A
C
T
G
H
S
K
R
H
R
Site 28
S156
S
R
A
C
T
G
H
S
K
R
H
R
S
R
A
Site 29
S161
G
H
S
K
R
H
R
S
R
A
L
G
V
Q
T
Site 30
T168
S
R
A
L
G
V
Q
T
P
S
I
R
K
S
L
Site 31
S174
Q
T
P
S
I
R
K
S
L
V
T
S
V
R
A
Site 32
T177
S
I
R
K
S
L
V
T
S
V
R
A
M
S
E
Site 33
S178
I
R
K
S
L
V
T
S
V
R
A
M
S
E
A
Site 34
Y187
R
A
M
S
E
A
V
Y
Q
D
L
A
Q
V
W
Site 35
T203
Q
Q
I
H
S
P
L
T
C
E
Q
L
T
L
L
Site 36
T245
E
S
W
L
V
P
A
T
L
P
G
P
G
E
S
Site 37
T267
P
F
P
G
Q
E
I
T
E
T
V
S
G
S
D
Site 38
T269
P
G
Q
E
I
T
E
T
V
S
G
S
D
E
A
Site 39
S273
I
T
E
T
V
S
G
S
D
E
A
K
L
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation