KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
EGFLAM
Full Name:
Pikachurin
Alias:
AGRINL; AGRNL; DKFZp686O1697; EGFLA; EGF-like, fibronectin type III and laminin G domains; FLJ39155; Pikachurin
Type:
Unknown function
Mass (Da):
111271
Number AA:
1017
UniProt ID:
Q63HQ2
International Prot ID:
IPI00334254
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0045202
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S63
K
M
P
R
H
P
G
S
P
I
L
G
Y
T
V
Site 2
S73
L
G
Y
T
V
F
Y
S
E
V
G
A
D
K
S
Site 3
S80
S
E
V
G
A
D
K
S
L
Q
E
Q
L
H
S
Site 4
S87
S
L
Q
E
Q
L
H
S
V
P
L
S
R
D
I
Site 5
S91
Q
L
H
S
V
P
L
S
R
D
I
P
T
T
E
Site 6
T97
L
S
R
D
I
P
T
T
E
E
V
I
G
D
L
Site 7
T108
I
G
D
L
K
P
G
T
E
Y
R
V
S
I
A
Site 8
S113
P
G
T
E
Y
R
V
S
I
A
A
Y
S
Q
A
Site 9
Y117
Y
R
V
S
I
A
A
Y
S
Q
A
G
K
G
R
Site 10
S118
R
V
S
I
A
A
Y
S
Q
A
G
K
G
R
L
Site 11
S126
Q
A
G
K
G
R
L
S
S
P
R
H
V
T
T
Site 12
S127
A
G
K
G
R
L
S
S
P
R
H
V
T
T
L
Site 13
T132
L
S
S
P
R
H
V
T
T
L
S
Q
D
S
C
Site 14
T133
S
S
P
R
H
V
T
T
L
S
Q
D
S
C
L
Site 15
S135
P
R
H
V
T
T
L
S
Q
D
S
C
L
P
P
Site 16
S161
S
D
S
E
V
A
L
S
W
K
P
G
A
S
E
Site 17
S167
L
S
W
K
P
G
A
S
E
G
S
A
P
I
Q
Site 18
Y175
E
G
S
A
P
I
Q
Y
Y
S
V
E
F
I
R
Site 19
S177
S
A
P
I
Q
Y
Y
S
V
E
F
I
R
P
D
Site 20
S200
H
E
R
I
Q
M
D
S
M
V
I
K
G
L
D
Site 21
T210
I
K
G
L
D
P
D
T
N
Y
Q
F
A
V
R
Site 22
Y212
G
L
D
P
D
T
N
Y
Q
F
A
V
R
A
M
Site 23
S221
F
A
V
R
A
M
N
S
H
G
P
S
P
R
S
Site 24
S225
A
M
N
S
H
G
P
S
P
R
S
W
P
S
D
Site 25
S228
S
H
G
P
S
P
R
S
W
P
S
D
I
I
R
Site 26
S231
P
S
P
R
S
W
P
S
D
I
I
R
T
L
C
Site 27
T236
W
P
S
D
I
I
R
T
L
C
P
E
E
A
G
Site 28
S244
L
C
P
E
E
A
G
S
G
R
Y
G
P
R
Y
Site 29
Y251
S
G
R
Y
G
P
R
Y
I
T
D
M
G
A
G
Site 30
T253
R
Y
G
P
R
Y
I
T
D
M
G
A
G
E
D
Site 31
S273
D
D
L
D
L
D
I
S
F
E
E
V
K
P
L
Site 32
T283
E
V
K
P
L
P
A
T
K
G
G
N
K
K
F
Site 33
S298
L
V
E
S
K
K
M
S
I
S
N
P
K
T
I
Site 34
S300
E
S
K
K
M
S
I
S
N
P
K
T
I
S
R
Site 35
T304
M
S
I
S
N
P
K
T
I
S
R
L
I
P
P
Site 36
S306
I
S
N
P
K
T
I
S
R
L
I
P
P
T
S
Site 37
Y362
D
S
F
C
V
N
D
Y
T
W
G
G
S
R
C
Site 38
T372
G
G
S
R
C
Q
C
T
L
G
K
G
G
E
S
Site 39
S381
G
K
G
G
E
S
C
S
E
D
I
V
I
Q
Y
Site 40
Y388
S
E
D
I
V
I
Q
Y
P
Q
F
F
G
H
S
Site 41
Y396
P
Q
F
F
G
H
S
Y
V
T
F
E
P
L
K
Site 42
T398
F
F
G
H
S
Y
V
T
F
E
P
L
K
N
S
Site 43
S405
T
F
E
P
L
K
N
S
Y
Q
A
F
Q
I
T
Site 44
Y426
A
E
D
G
L
L
L
Y
C
G
E
N
E
H
G
Site 45
S439
H
G
R
G
D
F
M
S
L
A
I
I
R
R
S
Site 46
T473
I
K
L
G
G
W
H
T
V
M
L
Y
R
D
G
Site 47
Y477
G
W
H
T
V
M
L
Y
R
D
G
L
N
G
L
Site 48
T491
L
L
Q
L
N
N
G
T
P
V
T
G
Q
S
Q
Site 49
S497
G
T
P
V
T
G
Q
S
Q
G
Q
Y
S
K
I
Site 50
Y501
T
G
Q
S
Q
G
Q
Y
S
K
I
T
F
R
T
Site 51
S502
G
Q
S
Q
G
Q
Y
S
K
I
T
F
R
T
P
Site 52
T505
Q
G
Q
Y
S
K
I
T
F
R
T
P
L
Y
L
Site 53
T508
Y
S
K
I
T
F
R
T
P
L
Y
L
G
G
A
Site 54
T525
A
Y
W
L
V
R
A
T
G
T
N
R
G
F
Q
Site 55
T527
W
L
V
R
A
T
G
T
N
R
G
F
Q
G
C
Site 56
S537
G
F
Q
G
C
V
Q
S
L
A
V
N
G
R
R
Site 57
T606
R
H
C
E
D
A
F
T
L
T
I
P
Q
F
R
Site 58
S615
T
I
P
Q
F
R
E
S
L
R
S
Y
A
A
T
Site 59
S618
Q
F
R
E
S
L
R
S
Y
A
A
T
P
W
P
Site 60
Y619
F
R
E
S
L
R
S
Y
A
A
T
P
W
P
L
Site 61
T622
S
L
R
S
Y
A
A
T
P
W
P
L
E
P
Q
Site 62
Y631
W
P
L
E
P
Q
H
Y
L
S
F
M
E
F
E
Site 63
S633
L
E
P
Q
H
Y
L
S
F
M
E
F
E
I
T
Site 64
T640
S
F
M
E
F
E
I
T
F
R
P
D
S
G
D
Site 65
S645
E
I
T
F
R
P
D
S
G
D
G
V
L
L
Y
Site 66
Y652
S
G
D
G
V
L
L
Y
S
Y
D
T
G
S
K
Site 67
S653
G
D
G
V
L
L
Y
S
Y
D
T
G
S
K
D
Site 68
Y654
D
G
V
L
L
Y
S
Y
D
T
G
S
K
D
F
Site 69
T656
V
L
L
Y
S
Y
D
T
G
S
K
D
F
L
S
Site 70
S658
L
Y
S
Y
D
T
G
S
K
D
F
L
S
I
N
Site 71
S663
T
G
S
K
D
F
L
S
I
N
L
A
G
G
H
Site 72
S679
E
F
R
F
D
C
G
S
G
T
G
V
L
R
S
Site 73
T681
R
F
D
C
G
S
G
T
G
V
L
R
S
E
D
Site 74
S686
S
G
T
G
V
L
R
S
E
D
P
L
T
L
G
Site 75
T691
L
R
S
E
D
P
L
T
L
G
N
W
H
E
L
Site 76
S701
N
W
H
E
L
R
V
S
R
T
A
K
N
G
I
Site 77
T726
G
M
A
E
G
G
F
T
Q
I
K
C
N
T
D
Site 78
Y742
F
I
G
G
V
P
N
Y
D
D
V
K
K
N
S
Site 79
S798
A
P
C
A
H
G
G
S
C
R
P
R
K
E
G
Site 80
Y806
C
R
P
R
K
E
G
Y
D
C
D
C
P
L
G
Site 81
Y826
C
Q
K
E
C
G
N
Y
C
L
N
T
I
I
E
Site 82
Y845
P
Q
F
I
G
R
S
Y
L
T
Y
D
N
P
D
Site 83
Y848
I
G
R
S
Y
L
T
Y
D
N
P
D
I
L
K
Site 84
S858
P
D
I
L
K
R
V
S
G
S
R
S
N
V
F
Site 85
S862
K
R
V
S
G
S
R
S
N
V
F
M
R
F
K
Site 86
T870
N
V
F
M
R
F
K
T
T
A
K
D
G
L
L
Site 87
S883
L
L
L
W
R
G
D
S
P
M
R
P
N
S
D
Site 88
S889
D
S
P
M
R
P
N
S
D
F
I
S
L
G
L
Site 89
S893
R
P
N
S
D
F
I
S
L
G
L
R
D
G
A
Site 90
T940
D
G
Q
S
G
K
I
T
V
D
D
Y
G
A
R
Site 91
Y944
G
K
I
T
V
D
D
Y
G
A
R
T
G
K
S
Site 92
S951
Y
G
A
R
T
G
K
S
P
G
M
M
R
Q
L
Site 93
Y980
A
L
H
T
N
R
Q
Y
M
R
G
L
V
G
C
Site 94
Y997
H
F
T
L
S
T
D
Y
H
I
S
L
V
E
D
Site 95
S1000
L
S
T
D
Y
H
I
S
L
V
E
D
A
V
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation