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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C14orf135
Full Name:
Pecanex-like protein C14orf135
Alias:
Hepatitis C virus F protein-binding protein 2
Type:
Mass (Da):
132702
Number AA:
1172
UniProt ID:
Q63HM2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
D
V
P
L
L
N
D
Y
K
Q
D
F
F
L
K
Site 2
T23
F
L
K
R
F
P
Q
T
V
L
G
G
P
R
F
Site 3
Y34
G
P
R
F
K
L
G
Y
C
A
P
P
Y
I
Y
Site 4
Y71
L
G
I
L
K
D
Y
Y
T
A
A
L
S
G
G
Site 5
Y93
V
I
Q
F
T
S
L
Y
A
K
N
K
S
T
T
Site 6
S98
S
L
Y
A
K
N
K
S
T
T
V
E
R
I
L
Site 7
T106
T
T
V
E
R
I
L
T
T
D
I
L
A
E
E
Site 8
T119
E
E
D
E
H
E
F
T
S
C
T
G
A
E
T
Site 9
S120
E
D
E
H
E
F
T
S
C
T
G
A
E
T
V
Site 10
T122
E
H
E
F
T
S
C
T
G
A
E
T
V
K
F
Site 11
Y167
P
N
R
I
T
L
L
Y
G
S
T
G
G
T
A
Site 12
Y189
M
T
L
C
I
A
E
Y
S
L
I
V
N
T
A
Site 13
S190
T
L
C
I
A
E
Y
S
L
I
V
N
T
A
T
Site 14
T207
A
T
F
Q
T
Q
D
T
Y
E
I
I
P
L
M
Site 15
Y208
T
F
Q
T
Q
D
T
Y
E
I
I
P
L
M
R
Site 16
S284
E
F
G
L
G
G
S
S
M
S
T
H
L
R
L
Site 17
S340
G
H
K
I
G
T
K
S
K
D
L
P
S
G
P
Site 18
S345
T
K
S
K
D
L
P
S
G
P
E
K
H
F
S
Site 19
S380
L
H
H
F
A
G
F
S
Q
I
S
K
S
N
S
Site 20
S383
F
A
G
F
S
Q
I
S
K
S
N
S
Q
A
I
Site 21
S385
G
F
S
Q
I
S
K
S
N
S
Q
A
I
V
G
Site 22
S387
S
Q
I
S
K
S
N
S
Q
A
I
V
G
Y
G
Site 23
Y422
G
I
F
R
N
P
F
Y
P
K
D
V
Q
T
V
Site 24
T428
F
Y
P
K
D
V
Q
T
V
T
V
F
F
E
K
Site 25
T430
P
K
D
V
Q
T
V
T
V
F
F
E
K
Q
T
Site 26
T561
E
K
K
Q
R
R
K
T
T
A
T
L
C
I
L
Site 27
T562
K
K
Q
R
R
K
T
T
A
T
L
C
I
L
N
Site 28
S609
G
F
P
R
P
I
Q
S
W
P
G
A
A
G
T
Site 29
Y628
C
A
D
T
V
Y
Y
Y
Q
M
V
P
R
L
T
Site 30
Y656
L
L
L
P
G
S
H
Y
L
G
R
F
Q
D
R
Site 31
T689
K
G
L
E
L
Q
E
T
S
C
H
T
A
E
A
Site 32
Y711
E
D
A
F
E
Q
E
Y
T
R
V
C
S
L
N
Site 33
T712
D
A
F
E
Q
E
Y
T
R
V
C
S
L
N
E
Site 34
S716
Q
E
Y
T
R
V
C
S
L
N
E
H
F
G
N
Site 35
S744
S
D
A
R
N
V
L
S
G
I
I
D
S
H
E
Site 36
S749
V
L
S
G
I
I
D
S
H
E
N
L
K
E
F
Site 37
S806
N
T
L
P
P
P
K
S
P
E
D
I
D
S
L
Site 38
S812
K
S
P
E
D
I
D
S
L
N
S
E
T
F
N
Site 39
S815
E
D
I
D
S
L
N
S
E
T
F
N
D
W
S
Site 40
T817
I
D
S
L
N
S
E
T
F
N
D
W
S
D
D
Site 41
T849
Q
L
K
D
L
P
G
T
N
L
F
I
P
G
S
Site 42
S856
T
N
L
F
I
P
G
S
V
E
S
Q
R
V
G
Site 43
S859
F
I
P
G
S
V
E
S
Q
R
V
G
D
H
S
Site 44
S866
S
Q
R
V
G
D
H
S
T
G
T
V
P
E
N
Site 45
T869
V
G
D
H
S
T
G
T
V
P
E
N
D
L
Y
Site 46
Y883
Y
K
A
V
L
L
G
Y
P
A
V
D
K
G
K
Site 47
Y896
G
K
Q
E
D
M
P
Y
I
P
L
M
E
F
S
Site 48
S919
L
P
A
E
W
R
T
S
C
M
P
S
S
K
M
Site 49
S924
R
T
S
C
M
P
S
S
K
M
K
E
M
S
S
Site 50
S931
S
K
M
K
E
M
S
S
L
F
P
E
D
W
Y
Site 51
Y938
S
L
F
P
E
D
W
Y
Q
F
V
L
R
Q
L
Site 52
Y948
V
L
R
Q
L
E
C
Y
H
S
E
E
K
A
S
Site 53
S950
R
Q
L
E
C
Y
H
S
E
E
K
A
S
N
V
Site 54
S955
Y
H
S
E
E
K
A
S
N
V
L
E
E
I
A
Site 55
S991
G
I
D
N
M
A
P
S
P
G
H
I
L
R
V
Site 56
Y999
P
G
H
I
L
R
V
Y
G
G
V
L
P
W
S
Site 57
T1013
S
V
A
L
D
W
L
T
E
K
P
E
L
F
Q
Site 58
Y1028
L
A
L
K
A
F
R
Y
T
L
K
L
M
I
D
Site 59
Y1051
D
F
R
E
L
I
K
Y
L
E
E
Y
E
R
D
Site 60
Y1055
L
I
K
Y
L
E
E
Y
E
R
D
W
Y
I
G
Site 61
Y1060
E
E
Y
E
R
D
W
Y
I
G
L
V
S
D
E
Site 62
Y1079
A
I
L
Q
E
K
P
Y
L
F
S
L
G
Y
D
Site 63
Y1085
P
Y
L
F
S
L
G
Y
D
S
N
M
G
I
Y
Site 64
T1093
D
S
N
M
G
I
Y
T
G
R
V
L
S
L
Q
Site 65
S1098
I
Y
T
G
R
V
L
S
L
Q
E
L
L
I
Q
Site 66
S1137
N
D
D
E
E
R
Y
S
I
Q
A
H
P
L
L
Site 67
Y1159
A
A
E
P
P
L
G
Y
P
I
Y
S
S
K
P
Site 68
Y1162
P
P
L
G
Y
P
I
Y
S
S
K
P
L
H
I
Site 69
S1163
P
L
G
Y
P
I
Y
S
S
K
P
L
H
I
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation