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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ALS2CL
Full Name:
ALS2 C-terminal-like protein
Alias:
Type:
Mass (Da):
107748
Number AA:
953
UniProt ID:
Q60I27
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S39
L
P
A
A
P
D
P
S
D
P
W
G
R
E
C
Site 2
S56
L
L
Q
Q
L
H
K
S
S
Q
Q
L
W
E
V
Site 3
S67
L
W
E
V
T
E
E
S
L
H
S
L
Q
E
R
Site 4
S70
V
T
E
E
S
L
H
S
L
Q
E
R
L
R
Y
Site 5
Y77
S
L
Q
E
R
L
R
Y
P
D
S
T
G
L
E
Site 6
S80
E
R
L
R
Y
P
D
S
T
G
L
E
S
L
L
Site 7
T81
R
L
R
Y
P
D
S
T
G
L
E
S
L
L
L
Site 8
S123
Q
K
A
A
K
R
R
S
E
Y
W
R
G
Q
R
Site 9
Y125
A
A
K
R
R
S
E
Y
W
R
G
Q
R
K
A
Site 10
S138
K
A
L
R
Q
L
L
S
G
V
S
S
E
G
S
Site 11
S141
R
Q
L
L
S
G
V
S
S
E
G
S
V
G
A
Site 12
S145
S
G
V
S
S
E
G
S
V
G
A
S
L
G
Q
Site 13
S149
S
E
G
S
V
G
A
S
L
G
Q
A
L
H
Q
Site 14
T182
T
I
G
E
H
H
P
T
R
E
L
V
V
N
A
Site 15
S198
T
L
F
G
N
L
Q
S
F
M
K
Q
E
L
D
Site 16
T216
A
T
Q
A
L
W
H
T
L
R
G
R
L
R
D
Site 17
T227
R
L
R
D
V
L
C
T
P
A
H
R
L
L
Q
Site 18
S236
A
H
R
L
L
Q
D
S
Q
D
V
P
V
T
V
Site 19
T242
D
S
Q
D
V
P
V
T
V
A
P
L
R
A
E
Site 20
T268
L
Q
G
H
N
V
H
T
F
D
L
K
L
V
W
Site 21
T284
D
P
G
Q
D
G
C
T
F
H
L
L
T
P
E
Site 22
T289
G
C
T
F
H
L
L
T
P
E
E
E
F
S
F
Site 23
S295
L
T
P
E
E
E
F
S
F
C
A
K
D
S
Q
Site 24
S335
L
G
A
G
L
E
P
S
Q
P
P
D
C
R
C
Site 25
Y345
P
D
C
R
C
A
E
Y
T
F
Q
A
E
G
R
Site 26
T346
D
C
R
C
A
E
Y
T
F
Q
A
E
G
R
L
Site 27
Y358
G
R
L
C
Q
A
T
Y
E
G
E
W
C
R
G
Site 28
S402
I
R
L
L
P
Q
A
S
E
D
K
F
D
C
Y
Site 29
Y421
R
E
G
S
M
C
G
Y
G
I
C
E
Y
S
T
Site 30
Y426
C
G
Y
G
I
C
E
Y
S
T
D
E
V
Y
K
Site 31
Y432
E
Y
S
T
D
E
V
Y
K
G
Y
F
Q
E
G
Site 32
Y435
T
D
E
V
Y
K
G
Y
F
Q
E
G
L
R
H
Site 33
S449
H
G
F
G
V
L
E
S
G
P
Q
A
P
Q
P
Site 34
Y471
E
R
G
Q
R
S
G
Y
G
I
E
E
D
G
D
Site 35
Y483
D
G
D
R
G
E
R
Y
I
G
M
W
Q
A
G
Site 36
T509
A
G
V
C
Y
Q
G
T
F
Q
A
D
K
T
V
Site 37
S523
V
G
P
G
I
L
L
S
E
D
D
S
L
Y
E
Site 38
S527
I
L
L
S
E
D
D
S
L
Y
E
G
T
F
T
Site 39
Y529
L
S
E
D
D
S
L
Y
E
G
T
F
T
R
D
Site 40
T532
D
D
S
L
Y
E
G
T
F
T
R
D
L
T
L
Site 41
T534
S
L
Y
E
G
T
F
T
R
D
L
T
L
M
G
Site 42
T538
G
T
F
T
R
D
L
T
L
M
G
K
G
K
V
Site 43
S556
N
G
F
T
L
E
G
S
F
G
S
G
A
G
R
Site 44
S581
A
A
L
P
P
D
P
S
S
T
C
K
R
Q
L
Site 45
S582
A
L
P
P
D
P
S
S
T
C
K
R
Q
L
G
Site 46
T583
L
P
P
D
P
S
S
T
C
K
R
Q
L
G
V
Site 47
S597
V
G
A
F
P
V
E
S
R
W
Q
G
V
Y
S
Site 48
Y603
E
S
R
W
Q
G
V
Y
S
P
F
R
D
F
V
Site 49
S629
L
L
G
F
D
V
Q
S
S
R
E
L
R
R
S
Site 50
S636
S
S
R
E
L
R
R
S
Q
D
Y
L
S
C
E
Site 51
Y639
E
L
R
R
S
Q
D
Y
L
S
C
E
R
T
H
Site 52
S641
R
R
S
Q
D
Y
L
S
C
E
R
T
H
P
E
Site 53
T645
D
Y
L
S
C
E
R
T
H
P
E
D
S
V
G
Site 54
S650
E
R
T
H
P
E
D
S
V
G
S
M
E
D
I
Site 55
Y673
E
P
K
A
L
Q
L
Y
L
R
K
A
L
S
N
Site 56
S679
L
Y
L
R
K
A
L
S
N
S
L
H
P
L
G
Site 57
S681
L
R
K
A
L
S
N
S
L
H
P
L
G
K
L
Site 58
T749
A
L
E
E
D
E
D
T
E
T
R
D
L
Q
V
Site 59
T751
E
E
D
E
D
T
E
T
R
D
L
Q
V
H
G
Site 60
Y776
Y
S
E
L
F
T
L
Y
L
L
L
H
E
R
E
Site 61
S785
L
L
H
E
R
E
D
S
F
Y
S
Q
G
I
A
Site 62
Y787
H
E
R
E
D
S
F
Y
S
Q
G
I
A
N
L
Site 63
S788
E
R
E
D
S
F
Y
S
Q
G
I
A
N
L
S
Site 64
T819
L
W
P
L
K
D
L
T
L
T
S
N
Q
R
Y
Site 65
S822
L
K
D
L
T
L
T
S
N
Q
R
Y
S
L
V
Site 66
Y826
T
L
T
S
N
Q
R
Y
S
L
V
R
D
K
C
Site 67
S827
L
T
S
N
Q
R
Y
S
L
V
R
D
K
C
F
Site 68
S836
V
R
D
K
C
F
L
S
A
T
E
C
L
Q
K
Site 69
T847
C
L
Q
K
I
M
T
T
V
D
P
R
E
K
L
Site 70
Y861
L
E
V
L
E
R
T
Y
G
E
I
E
G
T
V
Site 71
T867
T
Y
G
E
I
E
G
T
V
S
R
V
L
G
R
Site 72
S869
G
E
I
E
G
T
V
S
R
V
L
G
R
E
Y
Site 73
Y876
S
R
V
L
G
R
E
Y
K
L
P
M
D
D
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation