PhosphoNET

           
Protein Info 
   
Short Name:  OTP
Full Name:  Homeobox protein orthopedia
Alias: 
Type: 
Mass (Da):  34159
Number AA:  325
UniProt ID:  Q5XKR4
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S36CRLGVGGSDPGGHPG
Site 2S49PGDLAPNSDPVEGAT
Site 3T56SDPVEGATLLPGEDI
Site 4T65LPGEDITTVGSTPAS
Site 5S76TPASLAVSAKDPDKQ
Site 6S93PQGGPNPSQAGQQQG
Site 7T109QKQKRHRTRFTPAQL
Site 8T112KRHRTRFTPAQLNEL
Site 9S122QLNELERSFAKTHYP
Site 10T126LERSFAKTHYPDIFM
Site 11Y128RSFAKTHYPDIFMRE
Site 12S146LRIGLTESRVQVWFQ
Site 13T165KWKKRKKTTNVFRAP
Site 14S201AMGDSLCSFHANDTR
Site 15S235RQQAMAQSLSQCSLA
Site 16S240AQSLSQCSLAAGPPP
Site 17S249AAGPPPNSMGLSNSL
Site 18S253PPNSMGLSNSLAGSN
Site 19S255NSMGLSNSLAGSNGA
Site 20S259LSNSLAGSNGAGLQS
Site 21S266SNGAGLQSHLYQPAF
Site 22Y269AGLQSHLYQPAFPGM
Site 23S285PASLPGPSNVSGSPQ
Site 24S288LPGPSNVSGSPQLCS
Site 25S290GPSNVSGSPQLCSSP
Site 26S295SGSPQLCSSPDSSDV
Site 27S296GSPQLCSSPDSSDVW
Site 28S299QLCSSPDSSDVWRGT
Site 29S300LCSSPDSSDVWRGTS
Site 30T306SSDVWRGTSIASLRR
Site 31S307SDVWRGTSIASLRRK
Site 32S310WRGTSIASLRRKALE
Site 33T319RRKALEHTVSMSFT_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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