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Updated November 2019
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Protein Info
Short Name:
ZMYM4
Full Name:
Zinc finger MYM-type protein 4
Alias:
KIAA0425; MYM; Zinc finger protein 262; Zinc finger, MYM-type 4; ZNF198L3; ZNF262
Type:
DNA binding protein
Mass (Da):
172788
Number AA:
1548
UniProt ID:
Q5VZL5
International Prot ID:
IPI00477949
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0007275
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
E
R
E
V
E
S
G
P
R
K
R
F
E
Site 2
S18
R
K
R
F
E
Q
K
S
G
A
V
F
D
E
I
Site 3
T46
E
D
I
D
H
N
L
T
P
T
L
D
S
M
S
Site 4
T48
I
D
H
N
L
T
P
T
L
D
S
M
S
Y
G
Site 5
S51
N
L
T
P
T
L
D
S
M
S
Y
G
M
P
N
Site 6
S53
T
P
T
L
D
S
M
S
Y
G
M
P
N
Q
T
Site 7
Y54
P
T
L
D
S
M
S
Y
G
M
P
N
Q
T
G
Site 8
T60
S
Y
G
M
P
N
Q
T
G
S
E
N
S
L
L
Site 9
S62
G
M
P
N
Q
T
G
S
E
N
S
L
L
D
E
Site 10
Y72
S
L
L
D
E
D
D
Y
F
L
N
S
G
D
L
Site 11
S76
E
D
D
Y
F
L
N
S
G
D
L
A
G
I
P
Site 12
S87
A
G
I
P
V
V
G
S
D
N
E
D
E
Q
D
Site 13
S96
N
E
D
E
Q
D
F
S
S
K
D
N
L
V
S
Site 14
S97
E
D
E
Q
D
F
S
S
K
D
N
L
V
S
S
Site 15
S103
S
S
K
D
N
L
V
S
S
I
H
T
D
D
S
Site 16
S104
S
K
D
N
L
V
S
S
I
H
T
D
D
S
L
Site 17
T107
N
L
V
S
S
I
H
T
D
D
S
L
E
V
E
Site 18
S110
S
S
I
H
T
D
D
S
L
E
V
E
R
R
V
Site 19
T118
L
E
V
E
R
R
V
T
Q
H
E
S
D
N
E
Site 20
S122
R
R
V
T
Q
H
E
S
D
N
E
N
E
I
Q
Site 21
S146
P
K
Q
F
D
Q
V
S
V
F
K
S
I
R
K
Site 22
S150
D
Q
V
S
V
F
K
S
I
R
K
D
F
S
L
Site 23
S156
K
S
I
R
K
D
F
S
L
V
R
E
N
S
K
Site 24
S162
F
S
L
V
R
E
N
S
K
E
T
F
S
G
K
Site 25
T165
V
R
E
N
S
K
E
T
F
S
G
K
E
K
N
Site 26
T176
K
E
K
N
R
D
L
T
Y
E
R
E
K
R
L
Site 27
Y177
E
K
N
R
D
L
T
Y
E
R
E
K
R
L
D
Site 28
S192
K
P
H
K
D
L
D
S
R
L
K
S
S
F
F
Site 29
S196
D
L
D
S
R
L
K
S
S
F
F
D
K
A
A
Site 30
S197
L
D
S
R
L
K
S
S
F
F
D
K
A
A
N
Site 31
T212
Q
V
E
E
T
L
H
T
H
L
P
Q
T
P
E
Site 32
T217
L
H
T
H
L
P
Q
T
P
E
T
N
F
R
D
Site 33
T220
H
L
P
Q
T
P
E
T
N
F
R
D
S
S
Y
Site 34
S225
P
E
T
N
F
R
D
S
S
Y
P
F
A
N
K
Site 35
S226
E
T
N
F
R
D
S
S
Y
P
F
A
N
K
E
Site 36
Y227
T
N
F
R
D
S
S
Y
P
F
A
N
K
E
S
Site 37
S237
A
N
K
E
S
I
G
S
E
L
G
N
S
F
A
Site 38
Y258
E
E
P
L
D
D
E
Y
D
K
A
M
A
P
Q
Site 39
T290
S
H
G
Q
Q
Q
K
T
Q
E
G
E
L
K
I
Site 40
S298
Q
E
G
E
L
K
I
S
A
V
F
S
V
S
G
Site 41
T313
S
P
L
A
P
Q
L
T
T
G
F
Q
P
S
L
Site 42
S319
L
T
T
G
F
Q
P
S
L
A
S
S
G
M
N
Site 43
S323
F
Q
P
S
L
A
S
S
G
M
N
K
M
L
P
Site 44
Y355
L
Q
K
G
Q
T
A
Y
Q
R
K
G
S
T
Q
Site 45
S360
T
A
Y
Q
R
K
G
S
T
Q
L
F
C
S
T
Site 46
T385
A
R
P
P
P
P
L
T
K
K
T
C
S
S
C
Site 47
T388
P
P
P
L
T
K
K
T
C
S
S
C
S
K
D
Site 48
S390
P
L
T
K
K
T
C
S
S
C
S
K
D
I
L
Site 49
S391
L
T
K
K
T
C
S
S
C
S
K
D
I
L
N
Site 50
S393
K
K
T
C
S
S
C
S
K
D
I
L
N
P
K
Site 51
S404
L
N
P
K
D
V
I
S
A
Q
F
E
N
T
T
Site 52
T412
A
Q
F
E
N
T
T
T
S
K
D
F
C
S
Q
Site 53
S413
Q
F
E
N
T
T
T
S
K
D
F
C
S
Q
S
Site 54
S418
T
T
S
K
D
F
C
S
Q
S
C
L
S
T
Y
Site 55
S420
S
K
D
F
C
S
Q
S
C
L
S
T
Y
E
L
Site 56
T424
C
S
Q
S
C
L
S
T
Y
E
L
K
K
K
P
Site 57
Y425
S
Q
S
C
L
S
T
Y
E
L
K
K
K
P
I
Site 58
T437
K
P
I
V
T
I
N
T
N
S
I
S
T
K
C
Site 59
Y459
V
I
R
H
E
V
N
Y
Q
N
V
V
H
K
L
Site 60
S514
G
Q
S
K
K
F
C
S
S
S
C
I
T
A
Y
Site 61
S515
Q
S
K
K
F
C
S
S
S
C
I
T
A
Y
K
Site 62
S516
S
K
K
F
C
S
S
S
C
I
T
A
Y
K
Q
Site 63
T519
F
C
S
S
S
C
I
T
A
Y
K
Q
K
S
A
Site 64
Y521
S
S
S
C
I
T
A
Y
K
Q
K
S
A
K
I
Site 65
S525
I
T
A
Y
K
Q
K
S
A
K
I
T
P
C
A
Site 66
T529
K
Q
K
S
A
K
I
T
P
C
A
L
C
K
S
Site 67
S536
T
P
C
A
L
C
K
S
L
R
S
S
A
E
M
Site 68
S540
L
C
K
S
L
R
S
S
A
E
M
I
E
N
T
Site 69
S549
E
M
I
E
N
T
N
S
L
G
K
T
E
L
F
Site 70
T553
N
T
N
S
L
G
K
T
E
L
F
C
S
V
N
Site 71
S581
G
V
Q
V
Q
C
N
S
C
K
T
S
A
I
P
Site 72
Y590
K
T
S
A
I
P
Q
Y
H
L
A
M
S
D
G
Site 73
T619
Q
N
L
F
N
K
P
T
G
M
N
S
S
V
V
Site 74
S623
N
K
P
T
G
M
N
S
S
V
V
P
L
S
Q
Site 75
S624
K
P
T
G
M
N
S
S
V
V
P
L
S
Q
G
Site 76
S644
I
P
T
G
S
T
V
S
A
G
G
G
S
T
S
Site 77
T650
V
S
A
G
G
G
S
T
S
A
V
S
P
T
S
Site 78
S651
S
A
G
G
G
S
T
S
A
V
S
P
T
S
I
Site 79
S654
G
G
S
T
S
A
V
S
P
T
S
I
S
S
S
Site 80
T656
S
T
S
A
V
S
P
T
S
I
S
S
S
A
A
Site 81
S661
S
P
T
S
I
S
S
S
A
A
A
G
L
Q
R
Site 82
S673
L
Q
R
L
A
A
Q
S
Q
H
V
G
F
A
R
Site 83
S681
Q
H
V
G
F
A
R
S
V
V
K
L
K
C
Q
Site 84
Y703
T
K
P
E
L
L
D
Y
K
G
K
M
F
Q
F
Site 85
Y719
G
K
N
C
S
D
E
Y
K
K
I
N
N
V
M
Site 86
T741
I
E
K
I
V
K
E
T
V
R
F
S
G
A
D
Site 87
S745
V
K
E
T
V
R
F
S
G
A
D
K
S
F
C
Site 88
S750
R
F
S
G
A
D
K
S
F
C
S
E
G
C
K
Site 89
S753
G
A
D
K
S
F
C
S
E
G
C
K
L
L
Y
Site 90
Y760
S
E
G
C
K
L
L
Y
K
H
D
L
A
K
R
Site 91
Y806
C
E
E
C
M
S
K
Y
T
V
L
F
Y
Q
M
Site 92
Y811
S
K
Y
T
V
L
F
Y
Q
M
A
K
C
D
A
Site 93
S826
C
K
R
Q
G
K
L
S
E
S
L
K
W
R
G
Site 94
S828
R
Q
G
K
L
S
E
S
L
K
W
R
G
E
M
Site 95
S858
Q
S
V
C
D
P
P
S
Q
N
N
A
A
N
I
Site 96
S877
A
A
S
A
G
P
P
S
L
R
K
D
S
T
P
Site 97
S882
P
P
S
L
R
K
D
S
T
P
V
I
A
N
V
Site 98
T883
P
S
L
R
K
D
S
T
P
V
I
A
N
V
V
Site 99
T901
S
A
P
A
A
Q
P
T
V
N
S
N
S
V
L
Site 100
S906
Q
P
T
V
N
S
N
S
V
L
Q
G
A
V
P
Site 101
T925
K
I
I
G
D
A
S
T
Q
T
D
A
L
K
L
Site 102
S935
D
A
L
K
L
P
P
S
Q
P
P
R
L
L
K
Site 103
S958
I
T
Q
T
K
A
T
S
C
K
P
H
T
Q
N
Site 104
T963
A
T
S
C
K
P
H
T
Q
N
K
E
C
Q
T
Site 105
T973
K
E
C
Q
T
E
D
T
P
S
Q
P
Q
I
I
Site 106
S975
C
Q
T
E
D
T
P
S
Q
P
Q
I
I
V
V
Site 107
S1019
P
V
P
M
L
I
P
S
S
M
D
S
E
D
K
Site 108
S1020
V
P
M
L
I
P
S
S
M
D
S
E
D
K
V
Site 109
S1023
L
I
P
S
S
M
D
S
E
D
K
V
T
E
S
Site 110
T1028
M
D
S
E
D
K
V
T
E
S
I
E
D
I
K
Site 111
S1030
S
E
D
K
V
T
E
S
I
E
D
I
K
E
K
Site 112
T1040
D
I
K
E
K
L
P
T
H
P
F
E
A
D
L
Site 113
T1062
A
E
D
E
E
K
K
T
L
S
Q
G
E
S
Q
Site 114
S1064
D
E
E
K
K
T
L
S
Q
G
E
S
Q
T
S
Site 115
S1068
K
T
L
S
Q
G
E
S
Q
T
S
E
H
E
L
Site 116
T1070
L
S
Q
G
E
S
Q
T
S
E
H
E
L
F
L
Site 117
S1071
S
Q
G
E
S
Q
T
S
E
H
E
L
F
L
D
Site 118
S1088
I
F
E
K
D
Q
G
S
T
Y
S
G
D
L
E
Site 119
Y1090
E
K
D
Q
G
S
T
Y
S
G
D
L
E
S
E
Site 120
S1091
K
D
Q
G
S
T
Y
S
G
D
L
E
S
E
A
Site 121
S1096
T
Y
S
G
D
L
E
S
E
A
V
S
T
P
H
Site 122
S1100
D
L
E
S
E
A
V
S
T
P
H
S
W
E
E
Site 123
T1101
L
E
S
E
A
V
S
T
P
H
S
W
E
E
E
Site 124
S1104
E
A
V
S
T
P
H
S
W
E
E
E
L
N
H
Site 125
Y1112
W
E
E
E
L
N
H
Y
A
L
K
S
N
A
V
Site 126
S1116
L
N
H
Y
A
L
K
S
N
A
V
Q
E
A
D
Site 127
T1134
K
Q
F
S
K
G
E
T
E
Q
D
L
E
A
D
Site 128
S1144
D
L
E
A
D
F
P
S
D
S
F
D
P
L
N
Site 129
S1146
E
A
D
F
P
S
D
S
F
D
P
L
N
K
G
Site 130
S1160
G
Q
G
I
Q
A
R
S
R
T
R
R
R
H
R
Site 131
T1162
G
I
Q
A
R
S
R
T
R
R
R
H
R
D
G
Site 132
S1181
R
R
R
G
R
K
K
S
I
V
A
V
E
P
R
Site 133
S1239
C
G
G
V
E
Q
A
S
S
S
P
R
S
D
P
Site 134
S1240
G
G
V
E
Q
A
S
S
S
P
R
S
D
P
L
Site 135
S1241
G
V
E
Q
A
S
S
S
P
R
S
D
P
L
G
Site 136
S1244
Q
A
S
S
S
P
R
S
D
P
L
G
S
T
Q
Site 137
S1249
P
R
S
D
P
L
G
S
T
Q
D
H
A
L
S
Site 138
T1250
R
S
D
P
L
G
S
T
Q
D
H
A
L
S
Q
Site 139
S1256
S
T
Q
D
H
A
L
S
Q
E
S
S
E
P
G
Site 140
S1259
D
H
A
L
S
Q
E
S
S
E
P
G
C
R
V
Site 141
S1260
H
A
L
S
Q
E
S
S
E
P
G
C
R
V
R
Site 142
S1268
E
P
G
C
R
V
R
S
I
K
L
K
E
D
I
Site 143
Y1302
R
R
P
N
G
E
K
Y
D
P
D
S
I
L
Y
Site 144
S1306
G
E
K
Y
D
P
D
S
I
L
Y
L
C
L
G
Site 145
T1329
G
R
I
D
N
I
F
T
E
P
Y
S
R
F
M
Site 146
Y1332
D
N
I
F
T
E
P
Y
S
R
F
M
I
E
L
Site 147
S1358
L
P
N
G
Y
M
F
S
R
I
E
E
E
H
L
Site 148
Y1374
E
C
K
Q
L
G
A
Y
S
P
I
V
L
L
N
Site 149
S1375
C
K
Q
L
G
A
Y
S
P
I
V
L
L
N
T
Site 150
T1382
S
P
I
V
L
L
N
T
L
L
F
F
N
T
K
Site 151
S1403
V
T
E
H
L
K
L
S
F
A
H
V
M
R
R
Site 152
T1411
F
A
H
V
M
R
R
T
R
T
L
K
Y
S
T
Site 153
T1413
H
V
M
R
R
T
R
T
L
K
Y
S
T
K
M
Site 154
Y1416
R
R
T
R
T
L
K
Y
S
T
K
M
T
Y
L
Site 155
S1417
R
T
R
T
L
K
Y
S
T
K
M
T
Y
L
R
Site 156
T1421
L
K
Y
S
T
K
M
T
Y
L
R
F
F
P
P
Site 157
Y1422
K
Y
S
T
K
M
T
Y
L
R
F
F
P
P
L
Site 158
S1434
P
P
L
Q
K
Q
E
S
E
P
D
K
L
T
V
Site 159
T1440
E
S
E
P
D
K
L
T
V
G
K
R
K
R
N
Site 160
T1462
G
V
E
M
A
E
N
T
D
N
P
L
R
C
P
Site 161
Y1476
P
V
R
L
Y
E
F
Y
L
S
K
C
S
E
S
Site 162
S1478
R
L
Y
E
F
Y
L
S
K
C
S
E
S
V
K
Site 163
S1481
E
F
Y
L
S
K
C
S
E
S
V
K
Q
R
N
Site 164
Y1492
K
Q
R
N
D
V
F
Y
L
Q
P
E
R
S
C
Site 165
S1498
F
Y
L
Q
P
E
R
S
C
V
P
N
S
P
M
Site 166
Y1507
V
P
N
S
P
M
W
Y
S
T
F
P
I
D
P
Site 167
T1509
N
S
P
M
W
Y
S
T
F
P
I
D
P
G
T
Site 168
T1516
T
F
P
I
D
P
G
T
L
D
T
M
L
T
R
Site 169
T1519
I
D
P
G
T
L
D
T
M
L
T
R
I
L
M
Site 170
S1539
E
E
L
A
K
A
K
S
E
D
S
D
V
E
L
Site 171
S1542
A
K
A
K
S
E
D
S
D
V
E
L
S
D
_
Site 172
S1547
E
D
S
D
V
E
L
S
D
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation