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Updated November 2019
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Protein Info
Short Name:
C9orf84
Full Name:
Uncharacterized protein C9orf84
Alias:
Type:
Mass (Da):
165202
Number AA:
1444
UniProt ID:
Q5VXU9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T30
K
T
I
T
R
M
V
T
Q
I
N
C
E
F
E
Site 2
S42
E
F
E
E
V
V
P
S
S
N
P
D
S
Q
I
Site 3
S43
F
E
E
V
V
P
S
S
N
P
D
S
Q
I
E
Site 4
S47
V
P
S
S
N
P
D
S
Q
I
E
V
E
E
V
Site 5
Y57
E
V
E
E
V
S
L
Y
T
H
M
D
Y
N
E
Site 6
Y62
S
L
Y
T
H
M
D
Y
N
E
V
F
T
P
V
Site 7
T67
M
D
Y
N
E
V
F
T
P
V
S
C
L
E
K
Site 8
S96
D
K
G
I
L
F
V
S
S
R
K
H
L
P
T
Site 9
T103
S
S
R
K
H
L
P
T
L
P
T
L
L
S
R
Site 10
S134
I
F
T
E
A
N
F
S
R
E
C
F
S
L
Q
Site 11
S139
N
F
S
R
E
C
F
S
L
Q
E
T
L
E
A
Site 12
T143
E
C
F
S
L
Q
E
T
L
E
A
F
V
K
E
Site 13
S196
K
P
E
I
D
I
P
S
L
S
E
L
K
E
L
Site 14
S198
E
I
D
I
P
S
L
S
E
L
K
E
L
L
N
Site 15
Y213
P
V
P
E
I
I
N
Y
V
D
E
K
E
K
L
Site 16
T226
K
L
F
E
R
D
L
T
N
K
H
G
I
E
D
Site 17
S249
T
E
I
L
T
I
Q
S
Q
S
E
P
E
E
C
Site 18
S251
I
L
T
I
Q
S
Q
S
E
P
E
E
C
S
K
Site 19
S257
Q
S
E
P
E
E
C
S
K
P
G
E
L
E
M
Site 20
S276
L
F
L
T
C
Q
H
S
S
V
N
S
L
R
T
Site 21
S280
C
Q
H
S
S
V
N
S
L
R
T
E
L
Q
T
Site 22
T300
V
C
K
I
N
L
L
T
A
E
E
S
A
N
E
Site 23
Y308
A
E
E
S
A
N
E
Y
Y
M
M
W
Q
L
E
Site 24
Y309
E
E
S
A
N
E
Y
Y
M
M
W
Q
L
E
R
Site 25
S319
W
Q
L
E
R
C
R
S
P
L
N
P
F
L
L
Site 26
S336
P
R
I
Q
E
P
H
S
Q
Y
S
V
T
D
L
Site 27
S339
Q
E
P
H
S
Q
Y
S
V
T
D
L
K
K
I
Site 28
S348
T
D
L
K
K
I
F
S
V
K
E
E
S
L
V
Site 29
T376
L
N
L
K
M
M
E
T
L
E
H
L
N
T
Y
Site 30
T382
E
T
L
E
H
L
N
T
Y
L
C
H
D
N
L
Site 31
Y383
T
L
E
H
L
N
T
Y
L
C
H
D
N
L
S
Site 32
S390
Y
L
C
H
D
N
L
S
S
N
D
T
K
I
E
Site 33
T394
D
N
L
S
S
N
D
T
K
I
E
I
F
L
P
Site 34
S415
E
S
C
L
E
H
K
S
H
S
S
P
I
A
L
Site 35
S417
C
L
E
H
K
S
H
S
S
P
I
A
L
I
D
Site 36
S418
L
E
H
K
S
H
S
S
P
I
A
L
I
D
E
Site 37
S433
K
S
T
N
A
H
L
S
L
P
Q
K
S
P
S
Site 38
S438
H
L
S
L
P
Q
K
S
P
S
L
A
K
E
V
Site 39
S440
S
L
P
Q
K
S
P
S
L
A
K
E
V
P
D
Site 40
S451
E
V
P
D
L
C
F
S
D
D
Y
F
S
D
K
Site 41
Y454
D
L
C
F
S
D
D
Y
F
S
D
K
G
A
A
Site 42
T491
D
H
F
E
L
D
C
T
G
P
S
I
K
S
P
Site 43
S494
E
L
D
C
T
G
P
S
I
K
S
P
S
S
S
Site 44
S497
C
T
G
P
S
I
K
S
P
S
S
S
I
I
K
Site 45
S499
G
P
S
I
K
S
P
S
S
S
I
I
K
K
A
Site 46
S500
P
S
I
K
S
P
S
S
S
I
I
K
K
A
S
Site 47
S501
S
I
K
S
P
S
S
S
I
I
K
K
A
S
F
Site 48
S507
S
S
I
I
K
K
A
S
F
E
H
G
K
K
Q
Site 49
S522
E
N
D
L
D
L
L
S
D
F
I
M
L
R
N
Site 50
Y531
F
I
M
L
R
N
K
Y
K
T
C
T
S
K
T
Site 51
T533
M
L
R
N
K
Y
K
T
C
T
S
K
T
E
V
Site 52
S536
N
K
Y
K
T
C
T
S
K
T
E
V
T
N
S
Site 53
T538
Y
K
T
C
T
S
K
T
E
V
T
N
S
D
E
Site 54
S543
S
K
T
E
V
T
N
S
D
E
K
H
D
K
E
Site 55
S553
K
H
D
K
E
A
C
S
L
T
L
Q
E
E
S
Site 56
T555
D
K
E
A
C
S
L
T
L
Q
E
E
S
P
I
Site 57
S560
S
L
T
L
Q
E
E
S
P
I
V
H
I
N
K
Site 58
T568
P
I
V
H
I
N
K
T
L
E
E
I
N
Q
E
Site 59
T578
E
I
N
Q
E
R
G
T
D
S
V
I
E
I
Q
Site 60
S580
N
Q
E
R
G
T
D
S
V
I
E
I
Q
A
S
Site 61
S587
S
V
I
E
I
Q
A
S
D
S
Q
C
Q
A
F
Site 62
T623
T
A
N
W
K
F
A
T
V
I
F
D
Q
T
R
Site 63
S641
K
E
Q
E
K
V
V
S
D
A
V
R
Q
G
T
Site 64
T648
S
D
A
V
R
Q
G
T
I
D
E
R
E
M
T
Site 65
T655
T
I
D
E
R
E
M
T
F
K
H
A
A
L
L
Site 66
Y683
S
L
D
T
A
L
G
Y
L
S
K
A
K
D
I
Site 67
S685
D
T
A
L
G
Y
L
S
K
A
K
D
I
Y
N
Site 68
Y691
L
S
K
A
K
D
I
Y
N
S
I
L
G
P
Y
Site 69
Y721
G
K
K
P
E
T
N
Y
K
I
Q
E
L
Q
C
Site 70
T770
K
I
E
G
L
T
L
T
V
L
H
S
N
E
R
Site 71
S774
L
T
L
T
V
L
H
S
N
E
R
K
D
F
L
Site 72
Y816
N
F
S
F
V
V
E
Y
N
Y
V
E
D
S
C
Site 73
Y818
S
F
V
V
E
Y
N
Y
V
E
D
S
C
W
T
Site 74
T851
D
T
V
L
E
R
S
T
L
L
D
R
F
G
G
Site 75
Y889
L
Q
L
L
E
S
N
Y
N
I
S
L
V
E
R
Site 76
S899
S
L
V
E
R
G
C
S
E
S
L
K
L
F
G
Site 77
S901
V
E
R
G
C
S
E
S
L
K
L
F
G
S
S
Site 78
Y932
Q
D
L
E
E
L
N
Y
E
K
A
S
D
N
I
Site 79
Y958
R
Y
C
W
I
I
L
Y
T
K
E
T
L
N
S
Site 80
S965
Y
T
K
E
T
L
N
S
E
Y
L
L
T
E
K
Site 81
T970
L
N
S
E
Y
L
L
T
E
K
T
L
H
H
L
Site 82
S1018
I
R
Q
I
A
D
H
S
L
M
T
S
K
R
D
Site 83
S1022
A
D
H
S
L
M
T
S
K
R
D
P
H
E
W
Site 84
S1033
P
H
E
W
L
D
K
S
W
L
K
V
S
P
S
Site 85
S1038
D
K
S
W
L
K
V
S
P
S
E
E
E
M
Y
Site 86
S1040
S
W
L
K
V
S
P
S
E
E
E
M
Y
L
L
Site 87
Y1045
S
P
S
E
E
E
M
Y
L
L
D
F
P
C
I
Site 88
S1104
T
S
L
F
K
I
G
S
S
S
I
T
K
S
P
Site 89
S1105
S
L
F
K
I
G
S
S
S
I
T
K
S
P
Q
Site 90
S1106
L
F
K
I
G
S
S
S
I
T
K
S
P
Q
I
Site 91
T1108
K
I
G
S
S
S
I
T
K
S
P
Q
I
S
S
Site 92
S1110
G
S
S
S
I
T
K
S
P
Q
I
S
S
P
Q
Site 93
S1114
I
T
K
S
P
Q
I
S
S
P
Q
E
N
R
N
Site 94
S1115
T
K
S
P
Q
I
S
S
P
Q
E
N
R
N
Q
Site 95
S1124
Q
E
N
R
N
Q
I
S
T
L
S
S
Q
S
S
Site 96
T1125
E
N
R
N
Q
I
S
T
L
S
S
Q
S
S
A
Site 97
S1127
R
N
Q
I
S
T
L
S
S
Q
S
S
A
S
D
Site 98
S1128
N
Q
I
S
T
L
S
S
Q
S
S
A
S
D
L
Site 99
S1131
S
T
L
S
S
Q
S
S
A
S
D
L
D
S
V
Site 100
S1133
L
S
S
Q
S
S
A
S
D
L
D
S
V
I
Q
Site 101
S1137
S
S
A
S
D
L
D
S
V
I
Q
E
H
N
E
Site 102
Y1145
V
I
Q
E
H
N
E
Y
Y
Q
Y
L
G
L
G
Site 103
Y1146
I
Q
E
H
N
E
Y
Y
Q
Y
L
G
L
G
E
Site 104
Y1148
E
H
N
E
Y
Y
Q
Y
L
G
L
G
E
T
V
Site 105
T1160
E
T
V
Q
E
D
K
T
T
I
L
N
D
N
S
Site 106
T1161
T
V
Q
E
D
K
T
T
I
L
N
D
N
S
S
Site 107
S1168
T
I
L
N
D
N
S
S
I
M
E
L
K
E
I
Site 108
T1183
S
S
F
L
P
P
V
T
S
Y
N
Q
T
S
Y
Site 109
Y1185
F
L
P
P
V
T
S
Y
N
Q
T
S
Y
W
K
Site 110
T1188
P
V
T
S
Y
N
Q
T
S
Y
W
K
D
S
S
Site 111
Y1190
T
S
Y
N
Q
T
S
Y
W
K
D
S
S
C
K
Site 112
S1194
Q
T
S
Y
W
K
D
S
S
C
K
S
N
I
G
Site 113
S1195
T
S
Y
W
K
D
S
S
C
K
S
N
I
G
Q
Site 114
S1198
W
K
D
S
S
C
K
S
N
I
G
Q
N
T
P
Site 115
T1204
K
S
N
I
G
Q
N
T
P
F
L
I
N
I
E
Site 116
S1212
P
F
L
I
N
I
E
S
R
R
P
A
Y
N
S
Site 117
Y1217
I
E
S
R
R
P
A
Y
N
S
F
L
N
H
S
Site 118
S1219
S
R
R
P
A
Y
N
S
F
L
N
H
S
D
S
Site 119
S1224
Y
N
S
F
L
N
H
S
D
S
E
S
D
V
F
Site 120
S1226
S
F
L
N
H
S
D
S
E
S
D
V
F
S
L
Site 121
S1228
L
N
H
S
D
S
E
S
D
V
F
S
L
G
L
Site 122
S1232
D
S
E
S
D
V
F
S
L
G
L
T
Q
M
N
Site 123
S1245
M
N
C
E
T
I
K
S
P
T
D
T
Q
K
R
Site 124
T1249
T
I
K
S
P
T
D
T
Q
K
R
V
S
V
V
Site 125
S1254
T
D
T
Q
K
R
V
S
V
V
P
R
F
I
N
Site 126
S1262
V
V
P
R
F
I
N
S
Q
K
R
R
T
H
E
Site 127
T1267
I
N
S
Q
K
R
R
T
H
E
A
K
G
F
I
Site 128
S1279
G
F
I
N
K
D
V
S
D
P
I
F
S
L
E
Site 129
S1284
D
V
S
D
P
I
F
S
L
E
G
T
Q
S
P
Site 130
T1288
P
I
F
S
L
E
G
T
Q
S
P
L
H
W
N
Site 131
S1290
F
S
L
E
G
T
Q
S
P
L
H
W
N
F
K
Site 132
Y1323
Q
T
A
C
N
K
L
Y
S
Q
K
G
N
L
F
Site 133
S1324
T
A
C
N
K
L
Y
S
Q
K
G
N
L
F
T
Site 134
S1338
T
D
Q
Q
K
C
L
S
D
E
S
E
G
L
T
Site 135
T1345
S
D
E
S
E
G
L
T
C
E
S
S
K
D
E
Site 136
S1348
S
E
G
L
T
C
E
S
S
K
D
E
T
F
W
Site 137
S1349
E
G
L
T
C
E
S
S
K
D
E
T
F
W
R
Site 138
T1353
C
E
S
S
K
D
E
T
F
W
R
E
L
P
S
Site 139
S1363
R
E
L
P
S
V
P
S
L
D
L
F
R
A
S
Site 140
S1370
S
L
D
L
F
R
A
S
D
S
N
A
N
Q
K
Site 141
Y1383
Q
K
E
F
N
S
L
Y
F
Y
Q
R
A
G
K
Site 142
Y1385
E
F
N
S
L
Y
F
Y
Q
R
A
G
K
S
L
Site 143
S1391
F
Y
Q
R
A
G
K
S
L
G
Q
K
R
H
H
Site 144
S1400
G
Q
K
R
H
H
E
S
S
F
N
S
G
D
K
Site 145
S1401
Q
K
R
H
H
E
S
S
F
N
S
G
D
K
E
Site 146
S1404
H
H
E
S
S
F
N
S
G
D
K
E
S
L
T
Site 147
S1409
F
N
S
G
D
K
E
S
L
T
G
F
M
C
S
Site 148
T1411
S
G
D
K
E
S
L
T
G
F
M
C
S
Q
L
Site 149
S1416
S
L
T
G
F
M
C
S
Q
L
P
Q
F
K
K
Site 150
Y1428
F
K
K
R
R
L
A
Y
E
K
V
P
G
R
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation