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Updated November 2019
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Protein Info
Short Name:
C10orf18
Full Name:
Uncharacterized protein C10orf18
Alias:
BA318E3.2; Chromosome 10 open reading frame 18; CJ018; FLJ20360; Uncharacterized protein C10orf18: Uncharacterized protein C10orf18
Type:
Unknown function
Mass (Da):
268843
Number AA:
2430
UniProt ID:
Q5VWN6
International Prot ID:
IPI00400873
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
P
P
A
H
K
S
I
L
E
R
S
E
N
Site 2
S13
H
K
S
I
L
E
R
S
E
N
V
L
M
S
P
Site 3
S19
R
S
E
N
V
L
M
S
P
W
K
G
K
L
I
Site 4
T47
T
Y
G
A
M
I
P
T
Q
L
P
Q
E
L
D
Site 5
Y57
P
Q
E
L
D
F
K
Y
V
M
K
V
S
S
L
Site 6
S63
K
Y
V
M
K
V
S
S
L
K
K
R
L
P
E
Site 7
Y78
A
A
F
R
K
Q
N
Y
L
E
E
K
V
C
F
Site 8
Y93
Q
D
L
C
F
N
L
Y
E
V
E
L
S
N
R
Site 9
S98
N
L
Y
E
V
E
L
S
N
R
Q
G
E
N
I
Site 10
T109
G
E
N
I
D
K
L
T
E
C
I
K
N
K
Q
Site 11
S139
L
T
S
S
A
L
L
S
E
P
D
F
G
G
K
Site 12
S158
H
G
L
H
L
F
R
S
P
L
S
T
G
V
K
Site 13
S161
H
L
F
R
S
P
L
S
T
G
V
K
D
L
K
Site 14
S194
A
L
L
E
T
K
K
S
L
P
E
E
R
I
H
Site 15
T204
E
E
R
I
H
P
N
T
L
V
K
R
H
F
Q
Site 16
Y214
K
R
H
F
Q
E
L
Y
K
A
D
R
S
P
S
Site 17
S219
E
L
Y
K
A
D
R
S
P
S
L
S
V
A
P
Site 18
S221
Y
K
A
D
R
S
P
S
L
S
V
A
P
Q
D
Site 19
S223
A
D
R
S
P
S
L
S
V
A
P
Q
D
R
M
Site 20
T234
Q
D
R
M
K
D
P
T
F
L
G
K
L
P
S
Site 21
S254
P
P
A
E
K
C
P
S
E
S
L
T
Q
L
N
Site 22
S256
A
E
K
C
P
S
E
S
L
T
Q
L
N
S
Y
Site 23
T258
K
C
P
S
E
S
L
T
Q
L
N
S
Y
F
S
Site 24
S262
E
S
L
T
Q
L
N
S
Y
F
S
D
P
S
A
Site 25
Y263
S
L
T
Q
L
N
S
Y
F
S
D
P
S
A
Y
Site 26
S265
T
Q
L
N
S
Y
F
S
D
P
S
A
Y
I
L
Site 27
S268
N
S
Y
F
S
D
P
S
A
Y
I
L
E
V
S
Site 28
S287
L
L
A
E
H
P
Q
S
P
C
V
S
D
G
I
Site 29
S291
H
P
Q
S
P
C
V
S
D
G
I
C
D
A
G
Site 30
S312
P
D
P
E
F
L
V
S
E
A
E
V
R
K
E
Site 31
T320
E
A
E
V
R
K
E
T
E
T
K
K
D
S
E
Site 32
T322
E
V
R
K
E
T
E
T
K
K
D
S
E
E
M
Site 33
S340
K
K
R
V
F
P
L
S
P
A
S
N
L
R
V
Site 34
S343
V
F
P
L
S
P
A
S
N
L
R
V
Q
P
K
Site 35
S354
V
Q
P
K
R
K
A
S
M
P
H
M
V
Q
S
Site 36
S376
P
F
P
K
R
T
A
S
R
A
D
N
S
S
D
Site 37
S381
T
A
S
R
A
D
N
S
S
D
S
P
T
T
L
Site 38
S382
A
S
R
A
D
N
S
S
D
S
P
T
T
L
K
Site 39
S384
R
A
D
N
S
S
D
S
P
T
T
L
K
L
V
Site 40
T386
D
N
S
S
D
S
P
T
T
L
K
L
V
K
G
Site 41
T387
N
S
S
D
S
P
T
T
L
K
L
V
K
G
Q
Site 42
S426
K
N
Q
E
A
P
I
S
K
D
V
P
V
P
T
Site 43
S444
R
A
R
K
Q
E
K
S
P
V
K
T
V
P
R
Site 44
T448
Q
E
K
S
P
V
K
T
V
P
R
A
K
P
P
Site 45
S459
A
K
P
P
V
K
K
S
P
Q
K
Q
R
V
N
Site 46
S489
P
V
K
G
E
T
A
S
K
L
Q
S
E
I
S
Site 47
S493
E
T
A
S
K
L
Q
S
E
I
S
R
G
C
Q
Site 48
S505
G
C
Q
E
D
G
I
S
I
N
S
V
Q
P
E
Site 49
S508
E
D
G
I
S
I
N
S
V
Q
P
E
N
T
T
Site 50
Y529
P
E
N
S
I
V
N
Y
D
S
Q
A
L
N
M
Site 51
S531
N
S
I
V
N
Y
D
S
Q
A
L
N
M
L
A
Site 52
S548
A
L
S
S
A
T
S
S
T
P
V
S
E
A
R
Site 53
T549
L
S
S
A
T
S
S
T
P
V
S
E
A
R
N
Site 54
S552
A
T
S
S
T
P
V
S
E
A
R
N
L
H
C
Site 55
S560
E
A
R
N
L
H
C
S
S
E
L
P
Q
N
D
Site 56
S561
A
R
N
L
H
C
S
S
E
L
P
Q
N
D
V
Site 57
S571
P
Q
N
D
V
L
L
S
K
E
N
S
L
R
G
Site 58
S575
V
L
L
S
K
E
N
S
L
R
G
T
S
D
H
Site 59
T579
K
E
N
S
L
R
G
T
S
D
H
E
Y
H
R
Site 60
S580
E
N
S
L
R
G
T
S
D
H
E
Y
H
R
G
Site 61
Y584
R
G
T
S
D
H
E
Y
H
R
G
V
K
T
Q
Site 62
T590
E
Y
H
R
G
V
K
T
Q
K
G
E
L
L
P
Site 63
S600
G
E
L
L
P
N
P
S
S
D
R
K
S
N
S
Site 64
S601
E
L
L
P
N
P
S
S
D
R
K
S
N
S
G
Site 65
S605
N
P
S
S
D
R
K
S
N
S
G
S
D
L
T
Site 66
S607
S
S
D
R
K
S
N
S
G
S
D
L
T
V
S
Site 67
S609
D
R
K
S
N
S
G
S
D
L
T
V
S
Q
D
Site 68
T612
S
N
S
G
S
D
L
T
V
S
Q
D
E
E
S
Site 69
S614
S
G
S
D
L
T
V
S
Q
D
E
E
S
L
V
Site 70
S619
T
V
S
Q
D
E
E
S
L
V
P
C
S
Q
A
Site 71
S624
E
E
S
L
V
P
C
S
Q
A
P
A
K
A
Q
Site 72
S641
L
T
E
E
M
L
E
S
S
D
A
S
Q
S
S
Site 73
S642
T
E
E
M
L
E
S
S
D
A
S
Q
S
S
S
Site 74
S645
M
L
E
S
S
D
A
S
Q
S
S
S
V
S
V
Site 75
S647
E
S
S
D
A
S
Q
S
S
S
V
S
V
E
H
Site 76
S648
S
S
D
A
S
Q
S
S
S
V
S
V
E
H
S
Site 77
S649
S
D
A
S
Q
S
S
S
V
S
V
E
H
S
Y
Site 78
S651
A
S
Q
S
S
S
V
S
V
E
H
S
Y
A
L
Site 79
T661
H
S
Y
A
L
L
L
T
E
H
S
K
K
H
L
Site 80
S664
A
L
L
L
T
E
H
S
K
K
H
L
Q
E
R
Site 81
S675
L
Q
E
R
E
I
L
S
P
L
F
P
R
N
G
Site 82
T683
P
L
F
P
R
N
G
T
K
S
P
E
A
A
T
Site 83
S685
F
P
R
N
G
T
K
S
P
E
A
A
T
P
V
Site 84
T690
T
K
S
P
E
A
A
T
P
V
G
K
V
M
P
Site 85
S724
K
P
K
D
R
P
P
S
A
R
V
K
K
S
S
Site 86
S730
P
S
A
R
V
K
K
S
S
C
S
R
I
V
L
Site 87
S731
S
A
R
V
K
K
S
S
C
S
R
I
V
L
S
Site 88
S733
R
V
K
K
S
S
C
S
R
I
V
L
S
C
D
Site 89
T751
K
I
T
F
K
C
E
T
E
Y
A
F
S
L
D
Site 90
Y753
T
F
K
C
E
T
E
Y
A
F
S
L
D
S
K
Site 91
S756
C
E
T
E
Y
A
F
S
L
D
S
K
Y
T
N
Site 92
Y761
A
F
S
L
D
S
K
Y
T
N
N
P
L
E
K
Site 93
T762
F
S
L
D
S
K
Y
T
N
N
P
L
E
K
T
Site 94
T769
T
N
N
P
L
E
K
T
V
V
R
A
L
H
G
Site 95
S810
N
Q
N
K
I
I
R
S
S
R
K
V
V
E
H
Site 96
S811
Q
N
K
I
I
R
S
S
R
K
V
V
E
H
S
Site 97
Y823
E
H
S
N
P
A
K
Y
V
S
I
N
S
T
L
Site 98
S825
S
N
P
A
K
Y
V
S
I
N
S
T
L
E
S
Site 99
T829
K
Y
V
S
I
N
S
T
L
E
S
C
E
L
R
Site 100
S832
S
I
N
S
T
L
E
S
C
E
L
R
E
I
E
Site 101
S841
E
L
R
E
I
E
E
S
L
G
L
E
K
C
S
Site 102
S848
S
L
G
L
E
K
C
S
A
D
S
L
L
E
T
Site 103
S851
L
E
K
C
S
A
D
S
L
L
E
T
N
E
I
Site 104
T855
S
A
D
S
L
L
E
T
N
E
I
S
R
A
H
Site 105
S867
R
A
H
A
A
E
V
S
F
R
D
P
N
C
L
Site 106
T897
V
Q
N
E
Q
K
K
T
F
A
R
E
C
D
P
Site 107
T906
A
R
E
C
D
P
D
T
Q
E
D
Q
N
F
I
Site 108
S929
G
E
E
A
K
Q
E
S
L
E
T
S
N
L
V
Site 109
T932
A
K
Q
E
S
L
E
T
S
N
L
V
L
S
G
Site 110
S933
K
Q
E
S
L
E
T
S
N
L
V
L
S
G
I
Site 111
S938
E
T
S
N
L
V
L
S
G
I
G
S
T
Q
T
Site 112
S942
L
V
L
S
G
I
G
S
T
Q
T
N
G
P
S
Site 113
T945
S
G
I
G
S
T
Q
T
N
G
P
S
V
P
S
Site 114
S949
S
T
Q
T
N
G
P
S
V
P
S
E
E
E
I
Site 115
S962
E
I
V
Q
P
L
D
S
T
R
V
A
S
Y
S
Site 116
S967
L
D
S
T
R
V
A
S
Y
S
G
T
V
T
Q
Site 117
S969
S
T
R
V
A
S
Y
S
G
T
V
T
Q
A
T
Site 118
T971
R
V
A
S
Y
S
G
T
V
T
Q
A
T
F
T
Site 119
T973
A
S
Y
S
G
T
V
T
Q
A
T
F
T
R
T
Site 120
T976
S
G
T
V
T
Q
A
T
F
T
R
T
Y
D
G
Site 121
Y981
Q
A
T
F
T
R
T
Y
D
G
P
G
S
Q
P
Site 122
S986
R
T
Y
D
G
P
G
S
Q
P
V
I
C
Q
S
Site 123
S994
Q
P
V
I
C
Q
S
S
V
Y
G
T
L
E
N
Site 124
S1025
Q
D
L
I
Q
H
G
S
P
I
N
N
E
C
H
Site 125
S1034
I
N
N
E
C
H
P
S
L
E
R
K
D
D
N
Site 126
T1053
V
I
N
P
E
P
I
T
L
T
F
E
K
N
A
Site 127
T1055
N
P
E
P
I
T
L
T
F
E
K
N
A
H
V
Site 128
T1071
I
Q
T
E
G
V
N
T
A
D
E
R
T
T
F
Site 129
T1077
N
T
A
D
E
R
T
T
F
K
K
E
L
I
K
Site 130
S1087
K
E
L
I
K
Q
V
S
P
A
A
S
L
R
H
Site 131
S1091
K
Q
V
S
P
A
A
S
L
R
H
P
V
S
T
Site 132
S1097
A
S
L
R
H
P
V
S
T
S
E
N
A
R
T
Site 133
T1098
S
L
R
H
P
V
S
T
S
E
N
A
R
T
Q
Site 134
S1099
L
R
H
P
V
S
T
S
E
N
A
R
T
Q
G
Site 135
T1104
S
T
S
E
N
A
R
T
Q
G
L
R
D
I
P
Site 136
S1112
Q
G
L
R
D
I
P
S
L
V
V
A
G
Q
K
Site 137
Y1123
A
G
Q
K
G
T
K
Y
L
C
A
S
S
V
G
Site 138
S1128
T
K
Y
L
C
A
S
S
V
G
G
E
T
L
D
Site 139
S1140
T
L
D
K
A
V
C
S
L
Q
K
E
T
P
L
Site 140
T1145
V
C
S
L
Q
K
E
T
P
L
P
V
S
L
P
Site 141
S1150
K
E
T
P
L
P
V
S
L
P
S
D
K
T
M
Site 142
S1167
E
A
L
S
L
A
K
S
S
S
H
L
S
P
S
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L
K
H
F
Site 295
T2272
P
G
D
V
L
D
H
T
Y
Q
E
L
F
R
A
Site 296
Y2273
G
D
V
L
D
H
T
Y
Q
E
L
F
R
A
G
Site 297
Y2320
R
W
K
W
L
L
H
Y
R
E
N
K
K
L
K
Site 298
S2334
K
E
D
E
R
V
D
S
T
A
H
K
K
N
I
Site 299
S2345
K
K
N
I
M
L
K
S
F
Q
S
A
N
I
I
Site 300
Y2357
N
I
I
E
L
L
H
Y
H
Q
C
D
S
R
S
Site 301
S2362
L
H
Y
H
Q
C
D
S
R
S
S
T
K
A
E
Site 302
S2364
Y
H
Q
C
D
S
R
S
S
T
K
A
E
I
L
Site 303
S2365
H
Q
C
D
S
R
S
S
T
K
A
E
I
L
K
Site 304
T2366
Q
C
D
S
R
S
S
T
K
A
E
I
L
K
C
Site 305
T2395
V
L
L
T
D
K
P
T
I
P
R
E
V
F
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation