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Updated November 2019
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Protein Info
Short Name:
NBPF6
Full Name:
Neuroblastoma breakpoint family member 6
Alias:
Type:
Mass (Da):
72239
Number AA:
638
UniProt ID:
Q5VWK0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
V
V
S
A
D
P
L
S
S
E
R
A
E
M
N
Site 2
S10
V
S
A
D
P
L
S
S
E
R
A
E
M
N
I
Site 3
S26
E
I
N
Q
E
L
R
S
Q
L
A
E
S
N
Q
Site 4
S51
I
T
Q
A
T
A
Y
S
L
A
N
Q
L
K
K
Site 5
Y59
L
A
N
Q
L
K
K
Y
K
C
E
E
Y
K
D
Site 6
S70
E
Y
K
D
I
I
D
S
V
L
R
D
E
L
Q
Site 7
S78
V
L
R
D
E
L
Q
S
M
E
K
L
A
E
K
Site 8
Y95
Q
A
E
E
L
R
Q
Y
K
A
L
V
H
S
Q
Site 9
S101
Q
Y
K
A
L
V
H
S
Q
A
K
E
L
T
Q
Site 10
S120
L
R
E
G
R
D
A
S
R
W
L
N
K
H
L
Site 11
T132
K
H
L
K
T
L
L
T
P
D
D
P
D
K
S
Site 12
S139
T
P
D
D
P
D
K
S
Q
G
Q
D
L
R
E
Site 13
S163
E
H
L
V
H
K
L
S
P
E
N
D
E
D
E
Site 14
S187
E
V
E
K
V
Q
E
S
P
A
P
R
E
V
Q
Site 15
T196
A
P
R
E
V
Q
K
T
E
E
K
E
V
P
Q
Site 16
S205
E
K
E
V
P
Q
D
S
L
E
E
C
A
V
T
Site 17
T212
S
L
E
E
C
A
V
T
C
S
N
S
H
N
P
Site 18
S214
E
E
C
A
V
T
C
S
N
S
H
N
P
S
N
Site 19
S216
C
A
V
T
C
S
N
S
H
N
P
S
N
S
N
Site 20
S220
C
S
N
S
H
N
P
S
N
S
N
Q
P
H
R
Site 21
S222
N
S
H
N
P
S
N
S
N
Q
P
H
R
S
T
Site 22
T229
S
N
Q
P
H
R
S
T
K
I
T
F
K
E
H
Site 23
T232
P
H
R
S
T
K
I
T
F
K
E
H
E
V
D
Site 24
S284
P
P
R
H
H
D
K
S
N
S
Y
R
H
R
E
Site 25
S286
R
H
H
D
K
S
N
S
Y
R
H
R
E
V
S
Site 26
S293
S
Y
R
H
R
E
V
S
F
L
A
L
D
E
Q
Site 27
Y312
A
Q
D
V
A
R
D
Y
S
N
P
K
W
D
E
Site 28
S313
Q
D
V
A
R
D
Y
S
N
P
K
W
D
E
T
Site 29
T320
S
N
P
K
W
D
E
T
S
L
G
F
L
E
K
Site 30
S329
L
G
F
L
E
K
Q
S
D
L
E
E
V
K
G
Site 31
T339
E
E
V
K
G
Q
E
T
V
A
P
R
L
S
R
Site 32
S345
E
T
V
A
P
R
L
S
R
G
P
L
R
V
D
Site 33
T375
P
S
I
L
P
D
L
T
P
S
Y
H
P
Y
W
Site 34
Y378
L
P
D
L
T
P
S
Y
H
P
Y
W
S
T
L
Site 35
Y381
L
T
P
S
Y
H
P
Y
W
S
T
L
Y
S
F
Site 36
T384
S
Y
H
P
Y
W
S
T
L
Y
S
F
E
D
K
Site 37
S387
P
Y
W
S
T
L
Y
S
F
E
D
K
Q
V
S
Site 38
S394
S
F
E
D
K
Q
V
S
L
A
L
V
D
K
I
Site 39
S412
Q
E
E
I
E
D
Q
S
P
P
C
P
R
L
S
Site 40
S419
S
P
P
C
P
R
L
S
Q
E
L
P
E
V
K
Site 41
S434
E
Q
E
V
P
E
D
S
V
N
E
V
Y
L
T
Site 42
Y439
E
D
S
V
N
E
V
Y
L
T
P
S
V
H
H
Site 43
T441
S
V
N
E
V
Y
L
T
P
S
V
H
H
D
V
Site 44
S443
N
E
V
Y
L
T
P
S
V
H
H
D
V
S
D
Site 45
Y455
V
S
D
C
H
Q
P
Y
S
S
T
L
S
S
L
Site 46
S456
S
D
C
H
Q
P
Y
S
S
T
L
S
S
L
E
Site 47
S457
D
C
H
Q
P
Y
S
S
T
L
S
S
L
E
D
Site 48
S460
Q
P
Y
S
S
T
L
S
S
L
E
D
Q
L
A
Site 49
S461
P
Y
S
S
T
L
S
S
L
E
D
Q
L
A
C
Site 50
T485
E
A
A
C
P
Q
G
T
W
S
G
D
L
S
H
Site 51
S487
A
C
P
Q
G
T
W
S
G
D
L
S
H
H
R
Site 52
S491
G
T
W
S
G
D
L
S
H
H
R
S
E
V
Q
Site 53
S495
G
D
L
S
H
H
R
S
E
V
Q
I
S
Q
A
Site 54
S500
H
R
S
E
V
Q
I
S
Q
A
Q
L
E
P
S
Site 55
T508
Q
A
Q
L
E
P
S
T
L
V
P
S
C
L
R
Site 56
S534
G
L
A
Q
R
G
L
S
S
T
T
C
S
F
S
Site 57
S535
L
A
Q
R
G
L
S
S
T
T
C
S
F
S
A
Site 58
T536
A
Q
R
G
L
S
S
T
T
C
S
F
S
A
N
Site 59
T537
Q
R
G
L
S
S
T
T
C
S
F
S
A
N
A
Site 60
S539
G
L
S
S
T
T
C
S
F
S
A
N
A
D
S
Site 61
S541
S
S
T
T
C
S
F
S
A
N
A
D
S
G
N
Site 62
S546
S
F
S
A
N
A
D
S
G
N
Q
W
P
F
Q
Site 63
S560
Q
E
L
V
L
E
P
S
L
G
M
K
N
P
P
Site 64
S579
D
A
L
E
G
S
A
S
N
T
Q
G
R
Q
V
Site 65
T581
L
E
G
S
A
S
N
T
Q
G
R
Q
V
T
G
Site 66
T587
N
T
Q
G
R
Q
V
T
G
R
I
R
A
S
L
Site 67
S608
I
R
R
R
L
P
F
S
K
W
R
L
A
F
R
Site 68
T629
E
S
A
E
I
P
N
T
A
E
R
M
Q
R
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation