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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GARNL3
Full Name:
GTPase-activating Rap/Ran-GAP domain-like protein 3
Alias:
Type:
Mass (Da):
112852
Number AA:
1013
UniProt ID:
Q5VVW2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
M
K
H
F
C
S
S
S
V
S
E
D
L
G
C
Site 2
S28
H
F
C
S
S
S
V
S
E
D
L
G
C
R
R
Site 3
S39
G
C
R
R
G
D
F
S
R
K
H
Y
G
S
V
Site 4
Y43
G
D
F
S
R
K
H
Y
G
S
V
E
L
L
I
Site 5
S45
F
S
R
K
H
Y
G
S
V
E
L
L
I
S
S
Site 6
S70
R
F
R
V
E
N
G
S
S
D
E
N
A
T
A
Site 7
S71
F
R
V
E
N
G
S
S
D
E
N
A
T
A
L
Site 8
T76
G
S
S
D
E
N
A
T
A
L
P
G
T
W
R
Site 9
T81
N
A
T
A
L
P
G
T
W
R
R
T
D
V
H
Site 10
T85
L
P
G
T
W
R
R
T
D
V
H
L
E
N
P
Site 11
Y94
V
H
L
E
N
P
E
Y
H
T
R
W
Y
F
K
Site 12
Y99
P
E
Y
H
T
R
W
Y
F
K
Y
F
L
G
Q
Site 13
Y111
L
G
Q
V
H
Q
N
Y
I
G
N
D
A
E
K
Site 14
S119
I
G
N
D
A
E
K
S
P
F
F
L
S
V
T
Site 15
S124
E
K
S
P
F
F
L
S
V
T
L
S
D
Q
N
Site 16
T126
S
P
F
F
L
S
V
T
L
S
D
Q
N
N
Q
Site 17
S128
F
F
L
S
V
T
L
S
D
Q
N
N
Q
R
V
Site 18
Y138
N
N
Q
R
V
P
Q
Y
R
A
I
L
W
R
K
Site 19
T146
R
A
I
L
W
R
K
T
G
T
Q
K
I
C
L
Site 20
Y155
T
Q
K
I
C
L
P
Y
S
P
T
K
T
L
S
Site 21
S156
Q
K
I
C
L
P
Y
S
P
T
K
T
L
S
V
Site 22
T158
I
C
L
P
Y
S
P
T
K
T
L
S
V
K
S
Site 23
S162
Y
S
P
T
K
T
L
S
V
K
S
I
L
S
A
Site 24
S200
V
L
E
E
Q
E
G
S
V
N
F
K
F
G
V
Site 25
T242
N
L
L
G
D
T
I
T
L
K
G
W
T
G
Y
Site 26
T255
G
Y
R
G
G
L
D
T
K
N
D
T
T
G
I
Site 27
T259
G
L
D
T
K
N
D
T
T
G
I
H
S
V
Y
Site 28
T260
L
D
T
K
N
D
T
T
G
I
H
S
V
Y
T
Site 29
Y266
T
T
G
I
H
S
V
Y
T
V
Y
Q
G
H
E
Site 30
T267
T
G
I
H
S
V
Y
T
V
Y
Q
G
H
E
I
Site 31
T280
E
I
M
F
H
V
S
T
M
L
P
Y
S
K
E
Site 32
S285
V
S
T
M
L
P
Y
S
K
E
N
K
Q
Q
V
Site 33
S313
V
F
Q
E
G
E
E
S
S
P
A
F
K
P
S
Site 34
S314
F
Q
E
G
E
E
S
S
P
A
F
K
P
S
M
Site 35
S320
S
S
P
A
F
K
P
S
M
I
R
S
H
F
T
Site 36
Y342
Y
N
Q
Q
N
D
N
Y
R
L
K
I
F
S
E
Site 37
S348
N
Y
R
L
K
I
F
S
E
E
S
V
P
L
F
Site 38
T389
G
E
K
A
T
L
E
T
P
T
F
A
Q
K
R
Site 39
T391
K
A
T
L
E
T
P
T
F
A
Q
K
R
R
R
Site 40
T399
F
A
Q
K
R
R
R
T
L
D
M
L
I
R
S
Site 41
S424
K
N
M
L
N
R
R
S
F
S
D
V
L
P
E
Site 42
S426
M
L
N
R
R
S
F
S
D
V
L
P
E
S
P
Site 43
S432
F
S
D
V
L
P
E
S
P
K
S
A
R
K
K
Site 44
S435
V
L
P
E
S
P
K
S
A
R
K
K
E
E
A
Site 45
S458
G
Q
A
L
K
L
K
S
I
V
R
G
D
A
P
Site 46
S471
A
P
S
S
L
A
A
S
G
I
C
K
K
E
P
Site 47
S519
L
V
D
D
D
L
P
S
V
P
V
F
D
R
T
Site 48
T526
S
V
P
V
F
D
R
T
L
P
V
K
Q
M
H
Site 49
S573
E
G
K
Q
A
G
K
S
R
S
D
C
R
E
N
Site 50
S575
K
Q
A
G
K
S
R
S
D
C
R
E
N
K
L
Site 51
T585
R
E
N
K
L
E
K
T
K
G
C
H
L
Y
A
Site 52
Y591
K
T
K
G
C
H
L
Y
A
I
N
T
H
H
S
Site 53
S622
T
R
K
H
N
K
P
S
G
V
T
S
T
S
L
Site 54
S626
N
K
P
S
G
V
T
S
T
S
L
L
S
P
L
Site 55
T627
K
P
S
G
V
T
S
T
S
L
L
S
P
L
S
Site 56
S628
P
S
G
V
T
S
T
S
L
L
S
P
L
S
E
Site 57
S634
T
S
L
L
S
P
L
S
E
S
P
V
E
E
F
Site 58
S636
L
L
S
P
L
S
E
S
P
V
E
E
F
Q
Y
Site 59
Y643
S
P
V
E
E
F
Q
Y
I
R
E
I
C
L
S
Site 60
T657
S
D
S
P
M
V
M
T
L
V
D
G
P
A
E
Site 61
S795
P
Q
L
Q
L
V
A
S
R
S
D
I
Y
F
T
Site 62
S811
T
A
A
V
N
E
V
S
S
G
G
S
S
K
G
Site 63
S815
N
E
V
S
S
G
G
S
S
K
G
A
S
A
R
Site 64
S816
E
V
S
S
G
G
S
S
K
G
A
S
A
R
N
Site 65
S820
G
G
S
S
K
G
A
S
A
R
N
S
P
Q
T
Site 66
S824
K
G
A
S
A
R
N
S
P
Q
T
P
P
G
R
Site 67
T827
S
A
R
N
S
P
Q
T
P
P
G
R
D
T
P
Site 68
T833
Q
T
P
P
G
R
D
T
P
V
F
P
S
S
L
Site 69
S839
D
T
P
V
F
P
S
S
L
G
E
G
E
I
Q
Site 70
S847
L
G
E
G
E
I
Q
S
K
N
L
Y
K
I
P
Site 71
Y851
E
I
Q
S
K
N
L
Y
K
I
P
L
R
N
L
Site 72
S862
L
R
N
L
V
G
R
S
I
E
R
P
L
K
S
Site 73
S896
I
P
V
T
H
S
L
S
L
S
R
M
E
I
K
Site 74
S898
V
T
H
S
L
S
L
S
R
M
E
I
K
E
I
Site 75
T909
I
K
E
I
A
S
R
T
R
R
E
L
L
G
L
Site 76
S917
R
R
E
L
L
G
L
S
D
E
G
G
P
K
S
Site 77
S924
S
D
E
G
G
P
K
S
E
G
A
P
K
A
K
Site 78
S932
E
G
A
P
K
A
K
S
K
P
R
K
R
L
E
Site 79
S941
P
R
K
R
L
E
E
S
Q
G
G
P
K
P
G
Site 80
S952
P
K
P
G
A
V
R
S
S
S
S
D
R
I
P
Site 81
S953
K
P
G
A
V
R
S
S
S
S
D
R
I
P
S
Site 82
S954
P
G
A
V
R
S
S
S
S
D
R
I
P
S
G
Site 83
S955
G
A
V
R
S
S
S
S
D
R
I
P
S
G
S
Site 84
S960
S
S
S
D
R
I
P
S
G
S
L
E
S
A
S
Site 85
S962
S
D
R
I
P
S
G
S
L
E
S
A
S
T
S
Site 86
S965
I
P
S
G
S
L
E
S
A
S
T
S
E
A
N
Site 87
S967
S
G
S
L
E
S
A
S
T
S
E
A
N
P
E
Site 88
T968
G
S
L
E
S
A
S
T
S
E
A
N
P
E
G
Site 89
S969
S
L
E
S
A
S
T
S
E
A
N
P
E
G
H
Site 90
S991
P
V
A
D
R
E
G
S
P
V
S
G
S
S
P
Site 91
S994
D
R
E
G
S
P
V
S
G
S
S
P
F
Q
L
Site 92
S996
E
G
S
P
V
S
G
S
S
P
F
Q
L
T
A
Site 93
S1005
P
F
Q
L
T
A
F
S
D
E
D
I
I
D
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation