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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AGAP7
Full Name:
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 7
Alias:
Centaurin-gamma-like family member 4
Type:
Mass (Da):
73211
Number AA:
663
UniProt ID:
Q5VUJ5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
L
T
C
R
V
H
P
S
V
S
L
E
F
D
Q
Site 2
S23
E
F
D
Q
Q
Q
G
S
V
C
P
S
E
S
E
Site 3
S27
Q
Q
G
S
V
C
P
S
E
S
E
I
Y
E
A
Site 4
S29
G
S
V
C
P
S
E
S
E
I
Y
E
A
G
A
Site 5
Y32
C
P
S
E
S
E
I
Y
E
A
G
A
E
D
R
Site 6
S81
E
A
L
E
F
N
P
S
A
N
P
E
A
S
T
Site 7
S94
S
T
I
F
Q
R
N
S
Q
T
D
V
V
E
I
Site 8
S104
D
V
V
E
I
R
R
S
N
C
T
N
H
V
S
Site 9
T107
E
I
R
R
S
N
C
T
N
H
V
S
T
V
H
Site 10
S116
H
V
S
T
V
H
F
S
Q
Q
Y
S
L
C
S
Site 11
T124
Q
Q
Y
S
L
C
S
T
I
F
L
D
D
S
T
Site 12
T153
L
E
I
P
H
H
I
T
Q
R
D
A
D
R
S
Site 13
S160
T
Q
R
D
A
D
R
S
L
S
I
P
D
E
Q
Site 14
S162
R
D
A
D
R
S
L
S
I
P
D
E
Q
L
H
Site 15
S170
I
P
D
E
Q
L
H
S
F
A
V
S
T
V
H
Site 16
S174
Q
L
H
S
F
A
V
S
T
V
H
I
T
K
N
Site 17
T175
L
H
S
F
A
V
S
T
V
H
I
T
K
N
R
Site 18
S187
K
N
R
N
G
G
G
S
L
N
N
Y
S
S
S
Site 19
Y191
G
G
G
S
L
N
N
Y
S
S
S
I
P
S
T
Site 20
S192
G
G
S
L
N
N
Y
S
S
S
I
P
S
T
P
Site 21
S193
G
S
L
N
N
Y
S
S
S
I
P
S
T
P
S
Site 22
S194
S
L
N
N
Y
S
S
S
I
P
S
T
P
S
T
Site 23
S197
N
Y
S
S
S
I
P
S
T
P
S
T
S
Q
E
Site 24
T198
Y
S
S
S
I
P
S
T
P
S
T
S
Q
E
D
Site 25
S200
S
S
I
P
S
T
P
S
T
S
Q
E
D
P
Q
Site 26
T201
S
I
P
S
T
P
S
T
S
Q
E
D
P
Q
F
Site 27
S202
I
P
S
T
P
S
T
S
Q
E
D
P
Q
F
S
Site 28
S209
S
Q
E
D
P
Q
F
S
V
P
P
T
A
N
T
Site 29
T213
P
Q
F
S
V
P
P
T
A
N
T
P
T
P
V
Site 30
T216
S
V
P
P
T
A
N
T
P
T
P
V
C
K
R
Site 31
T218
P
P
T
A
N
T
P
T
P
V
C
K
R
S
M
Site 32
S228
C
K
R
S
M
R
W
S
N
L
F
T
S
E
K
Site 33
T232
M
R
W
S
N
L
F
T
S
E
K
G
S
D
P
Site 34
S233
R
W
S
N
L
F
T
S
E
K
G
S
D
P
D
Site 35
S237
L
F
T
S
E
K
G
S
D
P
D
K
E
R
K
Site 36
T252
A
P
E
N
H
A
D
T
I
G
S
G
R
A
I
Site 37
S255
N
H
A
D
T
I
G
S
G
R
A
I
P
I
K
Site 38
T276
R
S
G
K
W
L
K
T
W
K
K
K
Y
V
T
Site 39
Y281
L
K
T
W
K
K
K
Y
V
T
L
C
S
N
G
Site 40
T283
T
W
K
K
K
Y
V
T
L
C
S
N
G
V
L
Site 41
Y292
C
S
N
G
V
L
T
Y
Y
S
S
L
G
D
Y
Site 42
Y293
S
N
G
V
L
T
Y
Y
S
S
L
G
D
Y
M
Site 43
S295
G
V
L
T
Y
Y
S
S
L
G
D
Y
M
K
Y
Site 44
Y299
Y
Y
S
S
L
G
D
Y
M
K
Y
I
H
K
K
Site 45
Y302
S
L
G
D
Y
M
K
Y
I
H
K
K
E
I
D
Site 46
S323
K
V
P
G
K
W
P
S
L
A
T
L
A
C
T
Site 47
T326
G
K
W
P
S
L
A
T
L
A
C
T
P
I
S
Site 48
S333
T
L
A
C
T
P
I
S
S
S
K
S
D
G
L
Site 49
S334
L
A
C
T
P
I
S
S
S
K
S
D
G
L
S
Site 50
S335
A
C
T
P
I
S
S
S
K
S
D
G
L
S
K
Site 51
S337
T
P
I
S
S
S
K
S
D
G
L
S
K
D
M
Site 52
S341
S
S
K
S
D
G
L
S
K
D
M
D
T
G
L
Site 53
T346
G
L
S
K
D
M
D
T
G
L
G
D
S
I
C
Site 54
T361
F
S
P
S
I
S
S
T
T
I
P
K
L
N
P
Site 55
S371
P
K
L
N
P
P
P
S
P
H
A
N
K
K
K
Site 56
Y405
W
H
F
E
A
T
T
Y
E
E
R
D
A
W
V
Site 57
S417
A
W
V
Q
A
I
Q
S
Q
I
L
A
S
L
Q
Site 58
S422
I
Q
S
Q
I
L
A
S
L
Q
S
C
E
S
S
Site 59
S425
Q
I
L
A
S
L
Q
S
C
E
S
S
K
S
K
Site 60
S428
A
S
L
Q
S
C
E
S
S
K
S
K
S
Q
L
Site 61
S429
S
L
Q
S
C
E
S
S
K
S
K
S
Q
L
T
Site 62
S431
Q
S
C
E
S
S
K
S
K
S
Q
L
T
S
Q
Site 63
S433
C
E
S
S
K
S
K
S
Q
L
T
S
Q
S
E
Site 64
S437
K
S
K
S
Q
L
T
S
Q
S
E
A
M
A
L
Site 65
S439
K
S
Q
L
T
S
Q
S
E
A
M
A
L
Q
S
Site 66
S485
E
C
S
G
I
H
R
S
L
G
T
R
L
S
R
Site 67
S491
R
S
L
G
T
R
L
S
R
V
R
S
L
E
L
Site 68
S495
T
R
L
S
R
V
R
S
L
E
L
D
D
W
P
Site 69
S511
E
L
R
K
V
M
S
S
I
G
N
D
L
A
N
Site 70
S519
I
G
N
D
L
A
N
S
I
W
E
G
S
S
Q
Site 71
S525
N
S
I
W
E
G
S
S
Q
G
R
T
K
P
T
Site 72
T529
E
G
S
S
Q
G
R
T
K
P
T
E
K
S
T
Site 73
S535
R
T
K
P
T
E
K
S
T
R
E
E
K
E
R
Site 74
S546
E
K
E
R
W
I
R
S
K
Y
E
E
K
L
F
Site 75
Y548
E
R
W
I
R
S
K
Y
E
E
K
L
F
L
A
Site 76
T572
G
Q
Q
L
L
R
A
T
A
D
E
D
L
Q
T
Site 77
T595
S
R
E
E
V
N
E
T
C
G
E
G
D
G
C
Site 78
T639
A
H
G
N
T
A
L
T
Y
A
R
Q
A
S
S
Site 79
Y640
H
G
N
T
A
L
T
Y
A
R
Q
A
S
S
Q
Site 80
S645
L
T
Y
A
R
Q
A
S
S
Q
E
C
I
N
V
Site 81
S646
T
Y
A
R
Q
A
S
S
Q
E
C
I
N
V
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation