KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SFMBT2
Full Name:
Scm-like with four MBT domains protein 2
Alias:
KIAA1617; Scm-like with four mbt domains 2; Scm-related gene containing four mbt domains 2; SMBT2
Type:
Unknown function
Mass (Da):
100563
Number AA:
894
UniProt ID:
Q5VUG0
International Prot ID:
IPI00010970
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
E
S
T
L
S
A
S
N
M
Q
D
P
Site 2
S8
M
E
S
T
L
S
A
S
N
M
Q
D
P
S
S
Site 3
S14
A
S
N
M
Q
D
P
S
S
S
P
L
E
K
C
Site 4
S15
S
N
M
Q
D
P
S
S
S
P
L
E
K
C
L
Site 5
S16
N
M
Q
D
P
S
S
S
P
L
E
K
C
L
G
Site 6
S24
P
L
E
K
C
L
G
S
A
N
G
N
G
D
L
Site 7
S33
N
G
N
G
D
L
D
S
E
E
G
S
S
L
E
Site 8
S37
D
L
D
S
E
E
G
S
S
L
E
E
T
G
F
Site 9
S38
L
D
S
E
E
G
S
S
L
E
E
T
G
F
N
Site 10
T42
E
G
S
S
L
E
E
T
G
F
N
W
G
E
Y
Site 11
Y49
T
G
F
N
W
G
E
Y
L
E
E
T
G
A
S
Site 12
S56
Y
L
E
E
T
G
A
S
A
A
P
H
T
S
F
Site 13
S62
A
S
A
A
P
H
T
S
F
K
H
V
E
I
S
Site 14
Y91
N
K
N
N
P
D
T
Y
W
V
A
T
I
I
T
Site 15
Y108
G
Q
L
L
L
L
R
Y
C
G
Y
G
E
D
R
Site 16
Y111
L
L
L
R
Y
C
G
Y
G
E
D
R
R
A
D
Site 17
Y151
P
D
A
I
K
E
K
Y
T
D
W
T
E
F
L
Site 18
T163
E
F
L
I
R
D
L
T
G
S
R
T
A
P
A
Site 19
S165
L
I
R
D
L
T
G
S
R
T
A
P
A
N
L
Site 20
T167
R
D
L
T
G
S
R
T
A
P
A
N
L
L
E
Site 21
S197
S
L
I
E
L
Q
D
S
Q
N
P
F
Q
Y
W
Site 22
Y203
D
S
Q
N
P
F
Q
Y
W
I
V
S
V
I
E
Site 23
Y220
G
G
R
L
R
L
R
Y
V
G
L
E
D
T
E
Site 24
T226
R
Y
V
G
L
E
D
T
E
S
Y
D
Q
W
L
Site 25
Y229
G
L
E
D
T
E
S
Y
D
Q
W
L
F
Y
L
Site 26
Y235
S
Y
D
Q
W
L
F
Y
L
D
Y
R
L
R
P
Site 27
Y238
Q
W
L
F
Y
L
D
Y
R
L
R
P
V
G
W
Site 28
Y251
G
W
C
Q
E
N
K
Y
R
M
D
P
P
S
E
Site 29
S257
K
Y
R
M
D
P
P
S
E
I
Y
P
L
K
M
Site 30
Y260
M
D
P
P
S
E
I
Y
P
L
K
M
A
S
E
Site 31
T271
M
A
S
E
W
K
C
T
L
E
K
S
L
I
D
Site 32
S275
W
K
C
T
L
E
K
S
L
I
D
A
A
K
F
Site 33
T301
D
L
R
S
H
F
F
T
V
G
M
K
L
E
T
Site 34
S343
D
D
L
R
P
E
P
S
K
L
S
M
L
C
H
Site 35
S346
R
P
E
P
S
K
L
S
M
L
C
H
A
D
S
Site 36
S368
W
C
L
K
N
G
V
S
L
T
P
P
K
G
Y
Site 37
T370
L
K
N
G
V
S
L
T
P
P
K
G
Y
S
G
Site 38
S376
L
T
P
P
K
G
Y
S
G
Q
D
F
D
W
A
Site 39
Y385
Q
D
F
D
W
A
D
Y
H
K
Q
H
G
A
Q
Site 40
T402
P
P
F
C
F
R
N
T
S
F
S
R
G
F
T
Site 41
S403
P
F
C
F
R
N
T
S
F
S
R
G
F
T
K
Site 42
T409
T
S
F
S
R
G
F
T
K
N
M
K
L
E
A
Site 43
Y472
G
W
C
E
A
N
S
Y
P
L
T
A
P
H
K
Site 44
T475
E
A
N
S
Y
P
L
T
A
P
H
K
T
V
S
Site 45
T480
P
L
T
A
P
H
K
T
V
S
Q
K
K
R
K
Site 46
S482
T
A
P
H
K
T
V
S
Q
K
K
R
K
I
A
Site 47
T500
P
E
K
Q
L
P
P
T
V
P
V
K
K
I
P
Site 48
T519
L
F
P
H
L
D
T
T
G
T
V
N
G
K
Y
Site 49
T521
P
H
L
D
T
T
G
T
V
N
G
K
Y
C
C
Site 50
Y542
H
R
C
F
S
G
P
Y
L
N
K
G
R
I
A
Site 51
S554
R
I
A
E
L
P
Q
S
V
G
P
G
K
C
V
Site 52
Y604
E
E
T
L
K
A
K
Y
R
G
K
T
Y
R
A
Site 53
T608
K
A
K
Y
R
G
K
T
Y
R
A
V
V
K
I
Site 54
Y609
A
K
Y
R
G
K
T
Y
R
A
V
V
K
I
V
Site 55
Y661
S
I
H
T
K
T
K
Y
T
Y
Y
Y
G
K
R
Site 56
Y664
T
K
T
K
Y
T
Y
Y
Y
G
K
R
K
K
I
Site 57
Y665
K
T
K
Y
T
Y
Y
Y
G
K
R
K
K
I
S
Site 58
S672
Y
G
K
R
K
K
I
S
K
P
P
I
G
E
S
Site 59
S679
S
K
P
P
I
G
E
S
N
P
D
S
G
H
P
Site 60
S683
I
G
E
S
N
P
D
S
G
H
P
K
P
A
R
Site 61
S697
R
R
R
K
R
R
K
S
I
F
V
Q
K
K
R
Site 62
S706
F
V
Q
K
K
R
R
S
S
A
V
D
F
T
A
Site 63
S707
V
Q
K
K
R
R
S
S
A
V
D
F
T
A
G
Site 64
T712
R
S
S
A
V
D
F
T
A
G
S
G
E
E
S
Site 65
S715
A
V
D
F
T
A
G
S
G
E
E
S
E
E
E
Site 66
S719
T
A
G
S
G
E
E
S
E
E
E
D
A
D
A
Site 67
T731
A
D
A
M
D
D
D
T
A
S
E
E
T
G
S
Site 68
S733
A
M
D
D
D
T
A
S
E
E
T
G
S
E
L
Site 69
S738
T
A
S
E
E
T
G
S
E
L
R
D
D
Q
T
Site 70
T745
S
E
L
R
D
D
Q
T
D
T
S
S
A
E
V
Site 71
T747
L
R
D
D
Q
T
D
T
S
S
A
E
V
P
S
Site 72
S748
R
D
D
Q
T
D
T
S
S
A
E
V
P
S
A
Site 73
S749
D
D
Q
T
D
T
S
S
A
E
V
P
S
A
R
Site 74
S754
T
S
S
A
E
V
P
S
A
R
P
R
R
A
V
Site 75
T762
A
R
P
R
R
A
V
T
L
R
S
G
S
E
P
Site 76
S765
R
R
A
V
T
L
R
S
G
S
E
P
V
R
R
Site 77
S767
A
V
T
L
R
S
G
S
E
P
V
R
R
P
P
Site 78
T778
R
R
P
P
P
E
R
T
R
R
G
R
G
A
P
Site 79
S788
G
R
G
A
P
A
A
S
S
A
E
E
G
E
K
Site 80
S789
R
G
A
P
A
A
S
S
A
E
E
G
E
K
C
Site 81
T799
E
G
E
K
C
P
P
T
K
P
E
G
T
E
D
Site 82
S819
E
E
R
L
V
L
E
S
N
P
L
E
W
T
V
Site 83
T825
E
S
N
P
L
E
W
T
V
T
D
V
V
R
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation