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Updated November 2019
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Protein Info
Short Name:
TTC39B
Full Name:
Tetratricopeptide repeat protein 39B
Alias:
Type:
Mass (Da):
70086
Number AA:
616
UniProt ID:
Q5VTQ0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
E
D
A
L
E
T
I
S
I
S
S
H
S
D
M
Site 2
S27
A
L
E
T
I
S
I
S
S
H
S
D
M
A
T
Site 3
S30
T
I
S
I
S
S
H
S
D
M
A
T
S
S
L
Site 4
T34
S
S
H
S
D
M
A
T
S
S
L
H
F
A
S
Site 5
S36
H
S
D
M
A
T
S
S
L
H
F
A
S
C
D
Site 6
S54
A
P
R
Q
R
G
A
S
T
V
S
S
S
S
S
Site 7
T55
P
R
Q
R
G
A
S
T
V
S
S
S
S
S
T
Site 8
S57
Q
R
G
A
S
T
V
S
S
S
S
S
T
K
V
Site 9
S58
R
G
A
S
T
V
S
S
S
S
S
T
K
V
D
Site 10
S59
G
A
S
T
V
S
S
S
S
S
T
K
V
D
L
Site 11
S61
S
T
V
S
S
S
S
S
T
K
V
D
L
K
S
Site 12
T62
T
V
S
S
S
S
S
T
K
V
D
L
K
S
G
Site 13
S68
S
T
K
V
D
L
K
S
G
L
E
E
C
A
V
Site 14
Y101
P
W
A
K
E
S
M
Y
H
A
L
G
Y
S
T
Site 15
Y144
C
Q
K
Y
R
K
K
Y
T
V
V
E
S
F
S
Site 16
T145
Q
K
Y
R
K
K
Y
T
V
V
E
S
F
S
S
Site 17
S149
K
K
Y
T
V
V
E
S
F
S
S
L
L
S
R
Site 18
S151
Y
T
V
V
E
S
F
S
S
L
L
S
R
G
S
Site 19
S155
E
S
F
S
S
L
L
S
R
G
S
L
E
Q
L
Site 20
S158
S
S
L
L
S
R
G
S
L
E
Q
L
S
E
E
Site 21
S163
R
G
S
L
E
Q
L
S
E
E
E
M
H
A
E
Site 22
Y173
E
M
H
A
E
I
C
Y
A
E
C
L
L
Q
K
Site 23
T203
K
G
G
L
K
I
R
T
S
Y
Q
I
Y
K
E
Site 24
S204
G
G
L
K
I
R
T
S
Y
Q
I
Y
K
E
C
Site 25
Y205
G
L
K
I
R
T
S
Y
Q
I
Y
K
E
C
L
Site 26
Y229
K
L
Q
Q
E
F
F
Y
E
F
E
G
G
V
K
Site 27
S278
L
Q
L
R
E
G
A
S
G
R
S
M
R
S
A
Site 28
S281
R
E
G
A
S
G
R
S
M
R
S
A
L
C
C
Site 29
S395
S
D
L
L
C
K
E
S
K
W
S
K
A
T
Y
Site 30
T427
A
T
N
E
N
V
V
T
L
F
R
Q
V
D
S
Site 31
S434
T
L
F
R
Q
V
D
S
L
K
Q
R
I
A
G
Site 32
S443
K
Q
R
I
A
G
K
S
I
P
T
E
K
F
A
Site 33
Y457
A
V
R
K
A
R
R
Y
S
A
S
L
P
A
P
Site 34
S458
V
R
K
A
R
R
Y
S
A
S
L
P
A
P
V
Site 35
S460
K
A
R
R
Y
S
A
S
L
P
A
P
V
K
L
Site 36
S485
W
N
G
F
S
I
V
S
K
R
K
D
L
S
E
Site 37
S491
V
S
K
R
K
D
L
S
E
N
L
L
V
T
V
Site 38
S507
K
A
E
A
A
L
Q
S
Q
N
F
N
S
F
S
Site 39
S512
L
Q
S
Q
N
F
N
S
F
S
V
D
D
E
C
Site 40
S514
S
Q
N
F
N
S
F
S
V
D
D
E
C
L
V
Site 41
Y554
E
S
E
K
L
L
K
Y
D
H
Y
L
V
P
F
Site 42
S568
F
T
L
F
E
L
A
S
L
Y
K
S
Q
G
E
Site 43
Y570
L
F
E
L
A
S
L
Y
K
S
Q
G
E
I
D
Site 44
S572
E
L
A
S
L
Y
K
S
Q
G
E
I
D
K
A
Site 45
Y590
L
E
T
A
R
N
N
Y
K
D
Y
S
L
E
S
Site 46
Y593
A
R
N
N
Y
K
D
Y
S
L
E
S
R
L
H
Site 47
S594
R
N
N
Y
K
D
Y
S
L
E
S
R
L
H
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation